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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IL1RAPL1
Full Name:
Interleukin-1 receptor accessory protein-like 1
Alias:
IL1R8; IL1RAPL; IL1RAPL-1; Interleukin 1 receptor accessory protein-like 1; IRPL1; MRX10; MRX21; MRX34; Oligophrenin-4; OPHN4; Three immunoglobulin domain-containing IL-1 receptor-related 2; TIGIRR-2; X-linked interleukin-1 receptor accessory protein-like 1
Type:
Receptor, misc.
Mass (Da):
79950
Number AA:
696
UniProt ID:
Q9NZN1
International Prot ID:
IPI00431738
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004888
PhosphoSite+
KinaseNET
Biological Process:
GO:0045087
GO:0007611
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
L
Y
A
T
F
T
Q
S
L
K
V
V
T
K
R
Site 2
T187
L
W
Y
K
E
C
R
T
K
T
W
R
P
S
I
Site 3
T228
G
G
F
V
V
R
R
T
T
E
L
T
V
T
A
Site 4
Y389
K
I
E
I
M
L
F
Y
R
N
H
F
G
A
E
Site 5
Y405
L
D
G
D
N
K
D
Y
D
A
Y
L
S
Y
T
Site 6
Y408
D
N
K
D
Y
D
A
Y
L
S
Y
T
K
V
D
Site 7
S410
K
D
Y
D
A
Y
L
S
Y
T
K
V
D
P
D
Site 8
T456
P
D
R
D
L
I
P
T
G
T
Y
I
E
D
V
Site 9
S488
Y
V
V
R
R
G
W
S
I
F
E
L
E
T
R
Site 10
Y521
E
L
R
G
I
M
N
Y
Q
E
V
E
A
L
K
Site 11
T535
K
H
T
I
K
L
L
T
V
I
K
W
H
G
P
Site 12
Y557
K
F
W
K
R
L
Q
Y
E
M
P
F
K
R
I
Site 13
T568
F
K
R
I
E
P
I
T
H
E
Q
A
L
D
V
Site 14
T610
A
H
P
D
L
R
S
T
F
H
N
T
Y
H
S
Site 15
Y615
R
S
T
F
H
N
T
Y
H
S
Q
M
R
Q
K
Site 16
Y624
S
Q
M
R
Q
K
H
Y
Y
R
S
Y
E
Y
D
Site 17
Y625
Q
M
R
Q
K
H
Y
Y
R
S
Y
E
Y
D
V
Site 18
Y628
Q
K
H
Y
Y
R
S
Y
E
Y
D
V
P
P
T
Site 19
Y630
H
Y
Y
R
S
Y
E
Y
D
V
P
P
T
G
T
Site 20
T641
P
T
G
T
L
P
L
T
S
I
G
N
Q
H
T
Site 21
S642
T
G
T
L
P
L
T
S
I
G
N
Q
H
T
Y
Site 22
Y649
S
I
G
N
Q
H
T
Y
C
N
I
P
M
T
L
Site 23
T664
I
N
G
Q
R
P
Q
T
K
S
S
R
E
Q
N
Site 24
S666
G
Q
R
P
Q
T
K
S
S
R
E
Q
N
P
D
Site 25
S667
Q
R
P
Q
T
K
S
S
R
E
Q
N
P
D
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation