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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EHD3
Full Name:
EH domain-containing protein 3
Alias:
EH domain containing 3; EHD2; EH-domain containing 3; PAST3
Type:
Recycling endosome membrane, Endosome, Plasma membrane, Nucleus, Endocytic vesicle protein
Mass (Da):
61896
Number AA:
546
UniProt ID:
Q9NZN3
International Prot ID:
IPI00021458
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005768
GO:0019898
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005525
GO:0003924
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
K
D
P
E
V
F
Q
T
V
S
E
G
L
K
K
Site 2
S22
P
E
V
F
Q
T
V
S
E
G
L
K
K
L
Y
Site 3
Y29
S
E
G
L
K
K
L
Y
K
S
K
L
L
P
L
Site 4
S31
G
L
K
K
L
Y
K
S
K
L
L
P
L
E
E
Site 5
S47
Y
R
F
H
E
F
H
S
P
A
L
E
D
A
D
Site 6
T72
G
Q
Y
S
T
G
K
T
T
F
I
R
Y
L
L
Site 7
T73
Q
Y
S
T
G
K
T
T
F
I
R
Y
L
L
E
Site 8
S96
G
P
E
P
T
T
D
S
F
I
A
V
M
Q
G
Site 9
S159
I
D
T
P
G
I
L
S
G
E
K
Q
R
I
S
Site 10
S166
S
G
E
K
Q
R
I
S
R
G
Y
D
F
A
A
Site 11
Y169
K
Q
R
I
S
R
G
Y
D
F
A
A
V
L
E
Site 12
S197
D
A
H
K
L
D
I
S
D
E
F
S
E
V
I
Site 13
S201
L
D
I
S
D
E
F
S
E
V
I
K
A
L
K
Site 14
S284
D
L
F
R
D
I
Q
S
L
P
R
N
A
A
L
Site 15
Y309
R
L
A
K
V
H
A
Y
I
I
S
S
L
K
K
Site 16
S313
V
H
A
Y
I
I
S
S
L
K
K
E
M
P
S
Site 17
Y339
V
N
N
L
A
E
I
Y
G
R
I
E
R
E
H
Site 18
S349
I
E
R
E
H
Q
I
S
P
G
D
F
P
N
L
Site 19
S376
S
K
F
Q
P
L
K
S
K
L
L
E
V
V
D
Site 20
S402
V
L
V
R
Q
E
E
S
Q
R
P
I
Q
M
V
Site 21
T417
K
G
G
A
F
E
G
T
L
H
G
P
F
G
H
Site 22
Y426
H
G
P
F
G
H
G
Y
G
E
G
A
G
E
G
Site 23
Y448
V
A
R
D
K
P
M
Y
D
E
I
F
Y
T
L
Site 24
Y453
P
M
Y
D
E
I
F
Y
T
L
S
P
V
D
G
Site 25
T454
M
Y
D
E
I
F
Y
T
L
S
P
V
D
G
K
Site 26
S456
D
E
I
F
Y
T
L
S
P
V
D
G
K
I
T
Site 27
S474
A
K
K
E
M
V
R
S
K
L
P
N
S
V
L
Site 28
S479
V
R
S
K
L
P
N
S
V
L
G
K
I
W
K
Site 29
S535
R
P
R
G
K
L
P
S
D
G
V
G
G
H
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation