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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C1RL
Full Name:
Complement C1r subcomponent-like protein
Alias:
Type:
Mass (Da):
53498
Number AA:
487
UniProt ID:
Q9NZP8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
G
P
R
V
W
G
K
Y
L
W
R
S
P
H
S
Site 2
T53
Q
E
L
P
Q
Q
L
T
S
P
G
Y
P
E
P
Site 3
S54
E
L
P
Q
Q
L
T
S
P
G
Y
P
E
P
Y
Site 4
Y57
Q
Q
L
T
S
P
G
Y
P
E
P
Y
G
K
G
Site 5
Y61
S
P
G
Y
P
E
P
Y
G
K
G
Q
E
S
S
Site 6
S67
P
Y
G
K
G
Q
E
S
S
T
D
I
K
A
P
Site 7
S68
Y
G
K
G
Q
E
S
S
T
D
I
K
A
P
E
Site 8
T69
G
K
G
Q
E
S
S
T
D
I
K
A
P
E
G
Site 9
S91
Q
D
F
D
L
E
P
S
Q
D
C
A
G
D
S
Site 10
S109
S
F
V
G
S
D
P
S
Q
F
C
G
Q
Q
G
Site 11
S117
Q
F
C
G
Q
Q
G
S
P
L
G
R
P
P
G
Site 12
S130
P
G
Q
R
E
F
V
S
S
G
R
S
L
R
L
Site 13
S131
G
Q
R
E
F
V
S
S
G
R
S
L
R
L
T
Site 14
S134
E
F
V
S
S
G
R
S
L
R
L
T
F
R
T
Site 15
T138
S
G
R
S
L
R
L
T
F
R
T
Q
P
S
S
Site 16
T141
S
L
R
L
T
F
R
T
Q
P
S
S
E
N
K
Site 17
S145
T
F
R
T
Q
P
S
S
E
N
K
T
A
H
L
Site 18
T149
Q
P
S
S
E
N
K
T
A
H
L
H
K
G
F
Site 19
Y167
Y
Q
T
V
A
V
N
Y
S
Q
P
I
S
E
A
Site 20
S168
Q
T
V
A
V
N
Y
S
Q
P
I
S
E
A
S
Site 21
S172
V
N
Y
S
Q
P
I
S
E
A
S
R
G
S
E
Site 22
S178
I
S
E
A
S
R
G
S
E
A
I
N
A
P
G
Site 23
Y200
N
H
C
Q
E
P
Y
Y
Q
A
A
A
A
G
A
Site 24
T212
A
G
A
L
T
C
A
T
P
G
T
W
K
D
R
Site 25
T237
P
V
C
G
R
P
V
T
P
I
A
Q
N
Q
T
Site 26
T244
T
P
I
A
Q
N
Q
T
T
L
G
S
S
R
A
Site 27
T245
P
I
A
Q
N
Q
T
T
L
G
S
S
R
A
K
Site 28
S248
Q
N
Q
T
T
L
G
S
S
R
A
K
L
G
N
Site 29
S290
H
T
I
Y
P
K
D
S
V
S
L
R
K
N
Q
Site 30
S292
I
Y
P
K
D
S
V
S
L
R
K
N
Q
S
V
Site 31
S298
V
S
L
R
K
N
Q
S
V
N
V
F
L
G
H
Site 32
T306
V
N
V
F
L
G
H
T
A
I
D
E
M
L
K
Site 33
Y328
R
V
V
V
H
P
D
Y
R
Q
N
E
S
H
N
Site 34
S333
P
D
Y
R
Q
N
E
S
H
N
F
S
G
D
I
Site 35
S337
Q
N
E
S
H
N
F
S
G
D
I
A
L
L
E
Site 36
Y367
L
P
D
N
E
T
L
Y
R
S
G
L
L
G
Y
Site 37
T386
G
M
E
M
G
W
L
T
T
E
L
K
Y
S
R
Site 38
Y391
W
L
T
T
E
L
K
Y
S
R
L
P
V
A
P
Site 39
S392
L
T
T
E
L
K
Y
S
R
L
P
V
A
P
R
Site 40
S430
G
D
E
T
Q
R
H
S
V
C
Q
G
D
S
G
Site 41
Y440
Q
G
D
S
G
S
V
Y
V
V
W
D
N
H
A
Site 42
Y469
C
G
E
G
Y
D
F
Y
T
K
V
L
S
Y
V
Site 43
T470
G
E
G
Y
D
F
Y
T
K
V
L
S
Y
V
D
Site 44
S474
D
F
Y
T
K
V
L
S
Y
V
D
W
I
K
G
Site 45
Y475
F
Y
T
K
V
L
S
Y
V
D
W
I
K
G
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation