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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRPM5
Full Name:
Transient receptor potential cation channel subfamily M member 5
Alias:
LTRPC5; MTR1; transient receptor potential cation channel, subfamily M, member 5
Type:
Mass (Da):
131451
Number AA:
1165
UniProt ID:
Q9NZQ8
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0004872
GO:0005244
PhosphoSite+
KinaseNET
Biological Process:
GO:0006811
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
V
Q
G
P
R
P
G
S
P
G
D
A
E
D
R
Site 2
S82
E
Q
P
F
A
M
K
S
W
L
R
D
V
L
R
Site 3
S124
G
Q
A
V
R
D
H
S
L
A
S
T
S
T
K
Site 4
T128
R
D
H
S
L
A
S
T
S
T
K
V
R
V
V
Site 5
Y162
Q
E
D
F
P
V
H
Y
P
E
D
D
G
G
S
Site 6
S169
Y
P
E
D
D
G
G
S
Q
G
P
L
C
S
L
Site 7
S175
G
S
Q
G
P
L
C
S
L
D
S
N
L
S
H
Site 8
T198
P
G
K
G
D
G
L
T
E
L
R
L
R
L
E
Site 9
S209
L
R
L
E
K
H
I
S
E
Q
R
A
G
Y
G
Site 10
Y215
I
S
E
Q
R
A
G
Y
G
G
T
G
S
I
E
Site 11
T236
L
V
N
G
D
P
N
T
L
E
R
I
S
R
A
Site 12
S241
P
N
T
L
E
R
I
S
R
A
V
E
Q
A
A
Site 13
S292
K
F
P
S
K
H
F
S
W
E
D
I
V
R
W
Site 14
S308
K
L
L
Q
N
I
T
S
H
Q
H
L
L
T
V
Site 15
T314
T
S
H
Q
H
L
L
T
V
Y
D
F
E
Q
E
Site 16
Y316
H
Q
H
L
L
T
V
Y
D
F
E
Q
E
G
S
Site 17
S323
Y
D
F
E
Q
E
G
S
E
E
L
D
T
V
I
Site 18
S340
A
L
V
K
A
C
K
S
H
S
Q
E
P
Q
D
Site 19
S342
V
K
A
C
K
S
H
S
Q
E
P
Q
D
Y
L
Site 20
Y348
H
S
Q
E
P
Q
D
Y
L
D
E
L
K
L
A
Site 21
Y412
D
V
A
D
F
L
T
Y
G
R
L
Q
E
L
Y
Site 22
Y419
Y
G
R
L
Q
E
L
Y
R
S
V
S
R
K
S
Site 23
S421
R
L
Q
E
L
Y
R
S
V
S
R
K
S
L
L
Site 24
S423
Q
E
L
Y
R
S
V
S
R
K
S
L
L
F
D
Site 25
S426
Y
R
S
V
S
R
K
S
L
L
F
D
L
L
Q
Site 26
T442
K
Q
E
E
A
R
L
T
L
A
G
L
G
T
Q
Site 27
S462
P
A
G
P
P
A
F
S
L
H
E
V
S
R
V
Site 28
Y482
Q
D
A
C
R
G
F
Y
Q
D
G
R
P
G
D
Site 29
T502
K
G
P
A
K
R
P
T
G
Q
K
W
L
L
D
Site 30
S514
L
L
D
L
N
Q
K
S
E
N
P
W
R
D
L
Site 31
T571
E
A
E
A
A
R
A
T
R
E
A
K
Y
E
R
Site 32
Y576
R
A
T
R
E
A
K
Y
E
R
L
A
L
D
L
Site 33
S585
R
L
A
L
D
L
F
S
E
C
Y
S
N
S
E
Site 34
S589
D
L
F
S
E
C
Y
S
N
S
E
A
R
A
F
Site 35
S591
F
S
E
C
Y
S
N
S
E
A
R
A
F
A
L
Site 36
S685
E
D
L
Q
D
L
D
S
L
D
T
E
K
S
P
Site 37
T688
Q
D
L
D
S
L
D
T
E
K
S
P
L
Y
G
Site 38
S691
D
S
L
D
T
E
K
S
P
L
Y
G
L
Q
S
Site 39
Y694
D
T
E
K
S
P
L
Y
G
L
Q
S
R
V
E
Site 40
S698
S
P
L
Y
G
L
Q
S
R
V
E
E
L
V
E
Site 41
S765
R
P
P
P
Q
G
P
S
G
P
E
V
T
L
Y
Site 42
T789
E
I
R
Q
G
F
F
T
D
E
D
T
H
L
V
Site 43
T793
G
F
F
T
D
E
D
T
H
L
V
K
K
F
T
Site 44
Y802
L
V
K
K
F
T
L
Y
V
G
D
N
W
N
K
Site 45
Y914
R
R
V
L
Y
R
P
Y
L
Q
I
F
G
Q
I
Site 46
T935
E
A
R
V
N
C
S
T
H
P
L
L
L
E
D
Site 47
S943
H
P
L
L
L
E
D
S
P
S
C
P
S
L
Y
Site 48
S945
L
L
L
E
D
S
P
S
C
P
S
L
Y
A
N
Site 49
S948
E
D
S
P
S
C
P
S
L
Y
A
N
W
L
V
Site 50
T966
L
V
T
F
L
L
V
T
N
V
L
L
M
N
L
Site 51
Y1004
R
Y
N
L
I
V
E
Y
H
E
R
P
A
L
A
Site 52
T1056
Q
K
V
V
T
W
E
T
V
Q
K
E
N
F
L
Site 53
S1064
V
Q
K
E
N
F
L
S
K
M
E
K
R
R
R
Site 54
S1073
M
E
K
R
R
R
D
S
E
G
E
V
L
R
K
Site 55
T1081
E
G
E
V
L
R
K
T
A
H
R
V
D
F
I
Site 56
Y1091
R
V
D
F
I
A
K
Y
L
G
G
L
R
E
Q
Site 57
S1131
A
Q
G
G
G
P
R
S
S
Q
H
C
G
E
G
Site 58
S1132
Q
G
G
G
P
R
S
S
Q
H
C
G
E
G
S
Site 59
S1139
S
Q
H
C
G
E
G
S
Q
L
V
A
A
D
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation