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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRP1B
Full Name:
Low-density lipoprotein receptor-related protein 1B
Alias:
Low-density lipoprotein receptor-related protein-deleted in tumor; LRPDIT; LRP-DIT
Type:
Membrane, Membrane fraction, Integral membrane protein
Mass (Da):
515498
Number AA:
4599
UniProt ID:
Q9NZR2
International Prot ID:
IPI00032063
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0015031
GO:0006898
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y390
L
V
Y
W
V
D
L
Y
L
D
Y
V
G
V
V
Site 2
Y1708
H
P
V
R
G
K
L
Y
W
T
D
G
N
T
I
Site 3
T1710
V
R
G
K
L
Y
W
T
D
G
N
T
I
N
M
Site 4
Y3948
F
N
P
G
G
I
F
Y
K
R
I
H
G
R
E
Site 5
Y4150
F
G
H
G
S
V
E
Y
L
A
L
N
I
D
K
Site 6
T4473
L
C
K
R
K
R
R
T
K
T
I
R
R
Q
P
Site 7
T4475
K
R
K
R
R
T
K
T
I
R
R
Q
P
I
I
Site 8
Y4495
V
E
I
G
N
P
S
Y
N
M
Y
E
V
D
H
Site 9
Y4498
G
N
P
S
Y
N
M
Y
E
V
D
H
D
H
N
Site 10
T4519
P
G
F
M
I
D
P
T
K
A
R
Y
I
G
G
Site 11
Y4523
I
D
P
T
K
A
R
Y
I
G
G
G
P
S
A
Site 12
S4529
R
Y
I
G
G
G
P
S
A
F
K
L
P
H
T
Site 13
T4536
S
A
F
K
L
P
H
T
A
P
P
I
Y
L
N
Site 14
Y4541
P
H
T
A
P
P
I
Y
L
N
S
D
L
K
G
Site 15
S4544
A
P
P
I
Y
L
N
S
D
L
K
G
P
L
T
Site 16
T4551
S
D
L
K
G
P
L
T
A
G
P
T
N
Y
S
Site 17
T4555
G
P
L
T
A
G
P
T
N
Y
S
N
P
V
Y
Site 18
Y4557
L
T
A
G
P
T
N
Y
S
N
P
V
Y
A
K
Site 19
Y4562
T
N
Y
S
N
P
V
Y
A
K
L
Y
M
D
G
Site 20
Y4566
N
P
V
Y
A
K
L
Y
M
D
G
Q
N
C
R
Site 21
S4575
D
G
Q
N
C
R
N
S
L
G
S
V
D
E
R
Site 22
S4578
N
C
R
N
S
L
G
S
V
D
E
R
K
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation