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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KCND2
Full Name:
Potassium voltage-gated channel subfamily D member 2
Alias:
KIAA1044; Kv4.2; Potassium channel Kv4.2; Potassium voltage-gated channel, Shal-related subfamily, member 2; RK5
Type:
Channel protein, potassium
Mass (Da):
70537
Number AA:
630
UniProt ID:
Q9NZV8
International Prot ID:
IPI00303270
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0009986
GO:0043197
GO:0008076
Uniprot
OncoNet
Molecular Function:
GO:0030955
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006813
GO:0001508
GO:0007268
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T38
P
R
Q
E
R
K
R
T
Q
D
A
L
I
V
L
Site 2
T54
V
S
G
T
R
F
Q
T
W
Q
D
T
L
E
R
Site 3
T58
R
F
Q
T
W
Q
D
T
L
E
R
Y
P
D
T
Site 4
Y62
W
Q
D
T
L
E
R
Y
P
D
T
L
L
G
S
Site 5
T65
T
L
E
R
Y
P
D
T
L
L
G
S
S
E
R
Site 6
S69
Y
P
D
T
L
L
G
S
S
E
R
D
F
F
Y
Site 7
S70
P
D
T
L
L
G
S
S
E
R
D
F
F
Y
H
Site 8
Y76
S
S
E
R
D
F
F
Y
H
P
E
T
Q
Q
Y
Site 9
Y83
Y
H
P
E
T
Q
Q
Y
F
F
D
R
D
P
D
Site 10
Y99
F
R
H
I
L
N
F
Y
R
T
G
K
L
H
Y
Site 11
Y106
Y
R
T
G
K
L
H
Y
P
R
H
E
C
I
S
Site 12
S113
Y
P
R
H
E
C
I
S
A
Y
D
E
E
L
A
Site 13
Y115
R
H
E
C
I
S
A
Y
D
E
E
L
A
F
F
Site 14
Y134
E
I
I
G
D
C
C
Y
E
E
Y
K
D
R
R
Site 15
Y137
G
D
C
C
Y
E
E
Y
K
D
R
R
R
E
N
Site 16
T154
R
L
Q
D
D
A
D
T
D
T
A
G
E
S
A
Site 17
T156
Q
D
D
A
D
T
D
T
A
G
E
S
A
L
P
Site 18
T164
A
G
E
S
A
L
P
T
M
T
A
R
Q
R
V
Site 19
T166
E
S
A
L
P
T
M
T
A
R
Q
R
V
W
R
Site 20
T180
R
A
F
E
N
P
H
T
S
T
M
A
L
V
F
Site 21
S212
E
T
V
P
C
G
S
S
P
G
H
I
K
E
L
Site 22
S253
L
R
L
A
A
A
P
S
R
Y
R
F
V
R
S
Site 23
S286
M
T
D
N
E
D
V
S
G
A
F
V
T
L
R
Site 24
S304
V
F
R
I
F
K
F
S
R
H
S
Q
G
L
R
Site 25
S307
I
F
K
F
S
R
H
S
Q
G
L
R
I
L
G
Site 26
S350
F
Y
A
E
K
G
S
S
A
S
K
F
T
S
I
Site 27
Y413
V
S
N
F
S
R
I
Y
H
Q
N
Q
R
A
D
Site 28
S438
A
R
I
R
A
A
K
S
G
S
A
N
A
Y
M
Site 29
S440
I
R
A
A
K
S
G
S
A
N
A
Y
M
Q
S
Site 30
Y444
K
S
G
S
A
N
A
Y
M
Q
S
K
R
N
G
Site 31
S447
S
A
N
A
Y
M
Q
S
K
R
N
G
L
L
S
Site 32
S454
S
K
R
N
G
L
L
S
N
Q
L
Q
S
S
E
Site 33
S459
L
L
S
N
Q
L
Q
S
S
E
D
E
Q
A
F
Site 34
S460
L
S
N
Q
L
Q
S
S
E
D
E
Q
A
F
V
Site 35
S468
E
D
E
Q
A
F
V
S
K
S
G
S
S
F
E
Site 36
S470
E
Q
A
F
V
S
K
S
G
S
S
F
E
T
Q
Site 37
S472
A
F
V
S
K
S
G
S
S
F
E
T
Q
H
H
Site 38
S473
F
V
S
K
S
G
S
S
F
E
T
Q
H
H
H
Site 39
T476
K
S
G
S
S
F
E
T
Q
H
H
H
L
L
H
Site 40
T508
E
S
C
M
E
V
A
T
V
N
R
P
S
S
H
Site 41
S513
V
A
T
V
N
R
P
S
S
H
S
P
S
L
S
Site 42
S514
A
T
V
N
R
P
S
S
H
S
P
S
L
S
S
Site 43
S516
V
N
R
P
S
S
H
S
P
S
L
S
S
Q
Q
Site 44
S518
R
P
S
S
H
S
P
S
L
S
S
Q
Q
G
V
Site 45
S520
S
S
H
S
P
S
L
S
S
Q
Q
G
V
T
S
Site 46
S521
S
H
S
P
S
L
S
S
Q
Q
G
V
T
S
T
Site 47
S527
S
S
Q
Q
G
V
T
S
T
C
C
S
R
R
H
Site 48
T528
S
Q
Q
G
V
T
S
T
C
C
S
R
R
H
K
Site 49
T537
C
S
R
R
H
K
K
T
F
R
I
P
N
A
N
Site 50
S546
R
I
P
N
A
N
V
S
G
S
H
Q
G
S
I
Site 51
S548
P
N
A
N
V
S
G
S
H
Q
G
S
I
Q
E
Site 52
S552
V
S
G
S
H
Q
G
S
I
Q
E
L
S
T
I
Site 53
T567
Q
I
R
C
V
E
R
T
P
L
S
N
S
R
S
Site 54
S570
C
V
E
R
T
P
L
S
N
S
R
S
S
L
N
Site 55
S572
E
R
T
P
L
S
N
S
R
S
S
L
N
A
K
Site 56
S574
T
P
L
S
N
S
R
S
S
L
N
A
K
M
E
Site 57
S575
P
L
S
N
S
R
S
S
L
N
A
K
M
E
E
Site 58
T602
T
A
I
I
S
I
P
T
P
P
V
T
T
P
E
Site 59
T606
S
I
P
T
P
P
V
T
T
P
E
G
D
D
R
Site 60
T607
I
P
T
P
P
V
T
T
P
E
G
D
D
R
P
Site 61
S616
E
G
D
D
R
P
E
S
P
E
Y
S
G
G
N
Site 62
Y619
D
R
P
E
S
P
E
Y
S
G
G
N
I
V
R
Site 63
S620
R
P
E
S
P
E
Y
S
G
G
N
I
V
R
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation