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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KCMF1
Full Name:
E3 ubiquitin-protein ligase KCMF1
Alias:
Type:
Mass (Da):
41945
Number AA:
381
UniProt ID:
Q9P0J7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
R
H
E
G
V
S
C
Site 2
S8
M
S
R
H
E
G
V
S
C
D
A
C
L
K
G
Site 3
Y22
G
N
F
R
G
R
R
Y
K
C
L
I
C
Y
D
Site 4
Y28
R
Y
K
C
L
I
C
Y
D
Y
D
L
C
A
S
Site 5
Y30
K
C
L
I
C
Y
D
Y
D
L
C
A
S
C
Y
Site 6
Y37
Y
D
L
C
A
S
C
Y
E
S
G
A
T
T
T
Site 7
S39
L
C
A
S
C
Y
E
S
G
A
T
T
T
R
H
Site 8
T42
S
C
Y
E
S
G
A
T
T
T
R
H
T
T
D
Site 9
T47
G
A
T
T
T
R
H
T
T
D
H
P
M
Q
C
Site 10
Y64
T
R
V
D
F
D
L
Y
Y
G
G
E
A
F
S
Site 11
Y65
R
V
D
F
D
L
Y
Y
G
G
E
A
F
S
V
Site 12
S71
Y
Y
G
G
E
A
F
S
V
E
Q
P
Q
S
F
Site 13
Y88
P
Y
C
G
K
M
G
Y
T
E
T
S
L
Q
E
Site 14
S92
K
M
G
Y
T
E
T
S
L
Q
E
H
V
T
S
Site 15
S99
S
L
Q
E
H
V
T
S
E
H
A
E
T
S
T
Site 16
T106
S
E
H
A
E
T
S
T
E
V
I
C
P
I
C
Site 17
T125
G
G
D
P
N
H
V
T
D
D
F
A
A
H
L
Site 18
T133
D
D
F
A
A
H
L
T
L
E
H
R
A
P
R
Site 19
S145
A
P
R
D
L
D
E
S
S
G
V
R
H
V
R
Site 20
S146
P
R
D
L
D
E
S
S
G
V
R
H
V
R
R
Site 21
S169
G
G
P
R
A
R
R
S
N
M
H
F
T
S
S
Site 22
T174
R
R
S
N
M
H
F
T
S
S
S
T
G
G
L
Site 23
S175
R
S
N
M
H
F
T
S
S
S
T
G
G
L
S
Site 24
S176
S
N
M
H
F
T
S
S
S
T
G
G
L
S
S
Site 25
S177
N
M
H
F
T
S
S
S
T
G
G
L
S
S
S
Site 26
T178
M
H
F
T
S
S
S
T
G
G
L
S
S
S
Q
Site 27
S182
S
S
S
T
G
G
L
S
S
S
Q
S
S
Y
S
Site 28
S183
S
S
T
G
G
L
S
S
S
Q
S
S
Y
S
P
Site 29
S184
S
T
G
G
L
S
S
S
Q
S
S
Y
S
P
S
Site 30
S186
G
G
L
S
S
S
Q
S
S
Y
S
P
S
N
R
Site 31
S187
G
L
S
S
S
Q
S
S
Y
S
P
S
N
R
E
Site 32
S189
S
S
S
Q
S
S
Y
S
P
S
N
R
E
A
M
Site 33
S191
S
Q
S
S
Y
S
P
S
N
R
E
A
M
D
P
Site 34
S204
D
P
I
A
E
L
L
S
Q
L
S
G
V
R
R
Site 35
S207
A
E
L
L
S
Q
L
S
G
V
R
R
S
A
G
Site 36
S212
Q
L
S
G
V
R
R
S
A
G
G
Q
L
N
S
Site 37
S219
S
A
G
G
Q
L
N
S
S
G
P
S
A
S
Q
Site 38
S220
A
G
G
Q
L
N
S
S
G
P
S
A
S
Q
L
Site 39
S223
Q
L
N
S
S
G
P
S
A
S
Q
L
Q
Q
L
Site 40
S225
N
S
S
G
P
S
A
S
Q
L
Q
Q
L
Q
M
Site 41
T250
A
A
R
Q
Q
L
E
T
A
R
N
A
T
R
R
Site 42
T255
L
E
T
A
R
N
A
T
R
R
T
N
T
S
S
Site 43
T258
A
R
N
A
T
R
R
T
N
T
S
S
V
T
T
Site 44
T260
N
A
T
R
R
T
N
T
S
S
V
T
T
T
I
Site 45
S261
A
T
R
R
T
N
T
S
S
V
T
T
T
I
T
Site 46
S262
T
R
R
T
N
T
S
S
V
T
T
T
I
T
Q
Site 47
T266
N
T
S
S
V
T
T
T
I
T
Q
S
T
A
T
Site 48
T268
S
S
V
T
T
T
I
T
Q
S
T
A
T
T
N
Site 49
S282
N
I
A
N
T
E
S
S
Q
Q
T
L
Q
N
S
Site 50
T285
N
T
E
S
S
Q
Q
T
L
Q
N
S
Q
F
L
Site 51
S289
S
Q
Q
T
L
Q
N
S
Q
F
L
L
T
R
L
Site 52
T304
N
D
P
K
M
S
E
T
E
R
Q
S
M
E
S
Site 53
S308
M
S
E
T
E
R
Q
S
M
E
S
E
R
A
D
Site 54
S311
T
E
R
Q
S
M
E
S
E
R
A
D
R
S
L
Site 55
S317
E
S
E
R
A
D
R
S
L
F
V
Q
E
L
L
Site 56
T327
V
Q
E
L
L
L
S
T
L
V
R
E
E
S
S
Site 57
S333
S
T
L
V
R
E
E
S
S
S
S
D
E
D
D
Site 58
S335
L
V
R
E
E
S
S
S
S
D
E
D
D
R
G
Site 59
S336
V
R
E
E
S
S
S
S
D
E
D
D
R
G
E
Site 60
S370
E
N
L
N
L
K
E
S
N
K
G
N
E
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation