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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RAI14
Full Name:
Ankycorbin
Alias:
Ankycorbin; Ankyrin repeat and coiled-coil structure-containing protein; DKFZp564G013; KIAA1334; NORPEG; Novel retinal pigment epithelial; Novel retinal pigment epithelial cell protein; RAI13; Retinoic acid induced 14; Retinoic acid-induced protein 14
Type:
Adaptor/scaffold
Mass (Da):
110041
Number AA:
980
UniProt ID:
Q9P0K7
International Prot ID:
IPI00759532
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005938
GO:0005856
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
L
K
A
K
F
R
K
S
D
T
N
E
W
N
K
Site 2
T13
A
K
F
R
K
S
D
T
N
E
W
N
K
N
D
Site 3
S37
G
D
A
E
K
V
A
S
L
L
G
K
K
G
A
Site 4
S45
L
L
G
K
K
G
A
S
A
T
K
H
D
S
E
Site 5
T47
G
K
K
G
A
S
A
T
K
H
D
S
E
G
K
Site 6
S51
A
S
A
T
K
H
D
S
E
G
K
T
A
F
H
Site 7
T55
K
H
D
S
E
G
K
T
A
F
H
L
A
A
A
Site 8
T84
V
D
V
T
A
Q
D
T
T
G
H
S
A
L
H
Site 9
S108
C
I
R
K
L
L
Q
S
K
C
P
A
E
S
V
Site 10
S114
Q
S
K
C
P
A
E
S
V
D
S
S
G
K
T
Site 11
S117
C
P
A
E
S
V
D
S
S
G
K
T
A
L
H
Site 12
S118
P
A
E
S
V
D
S
S
G
K
T
A
L
H
Y
Site 13
T121
S
V
D
S
S
G
K
T
A
L
H
Y
A
A
A
Site 14
S143
Q
I
L
C
E
H
K
S
P
I
N
L
K
D
L
Site 15
S180
D
H
G
A
D
V
N
S
R
N
K
S
G
R
T
Site 16
S184
D
V
N
S
R
N
K
S
G
R
T
A
L
M
L
Site 17
Y219
N
L
V
D
S
L
G
Y
N
A
L
H
Y
S
K
Site 18
Y224
L
G
Y
N
A
L
H
Y
S
K
L
S
E
N
A
Site 19
S239
G
I
Q
S
L
L
L
S
K
I
S
Q
D
A
D
Site 20
S242
S
L
L
L
S
K
I
S
Q
D
A
D
L
K
T
Site 21
T249
S
Q
D
A
D
L
K
T
P
T
K
P
K
Q
H
Site 22
T251
D
A
D
L
K
T
P
T
K
P
K
Q
H
D
Q
Site 23
S260
P
K
Q
H
D
Q
V
S
K
I
S
S
E
R
S
Site 24
S263
H
D
Q
V
S
K
I
S
S
E
R
S
G
T
P
Site 25
S264
D
Q
V
S
K
I
S
S
E
R
S
G
T
P
K
Site 26
S267
S
K
I
S
S
E
R
S
G
T
P
K
K
R
K
Site 27
T269
I
S
S
E
R
S
G
T
P
K
K
R
K
A
P
Site 28
S281
K
A
P
P
P
P
I
S
P
T
Q
L
S
D
V
Site 29
T283
P
P
P
P
I
S
P
T
Q
L
S
D
V
S
S
Site 30
S286
P
I
S
P
T
Q
L
S
D
V
S
S
P
R
S
Site 31
S289
P
T
Q
L
S
D
V
S
S
P
R
S
I
T
S
Site 32
S290
T
Q
L
S
D
V
S
S
P
R
S
I
T
S
T
Site 33
S293
S
D
V
S
S
P
R
S
I
T
S
T
P
L
S
Site 34
T295
V
S
S
P
R
S
I
T
S
T
P
L
S
G
K
Site 35
S296
S
S
P
R
S
I
T
S
T
P
L
S
G
K
E
Site 36
T297
S
P
R
S
I
T
S
T
P
L
S
G
K
E
S
Site 37
S300
S
I
T
S
T
P
L
S
G
K
E
S
V
F
F
Site 38
S304
T
P
L
S
G
K
E
S
V
F
F
A
E
P
P
Site 39
S317
P
P
F
K
A
E
I
S
S
I
R
E
N
K
D
Site 40
S318
P
F
K
A
E
I
S
S
I
R
E
N
K
D
R
Site 41
S327
R
E
N
K
D
R
L
S
D
S
T
T
G
A
D
Site 42
S329
N
K
D
R
L
S
D
S
T
T
G
A
D
S
L
Site 43
T330
K
D
R
L
S
D
S
T
T
G
A
D
S
L
L
Site 44
T331
D
R
L
S
D
S
T
T
G
A
D
S
L
L
D
Site 45
S335
D
S
T
T
G
A
D
S
L
L
D
I
S
S
E
Site 46
S340
A
D
S
L
L
D
I
S
S
E
A
D
Q
Q
D
Site 47
S341
D
S
L
L
D
I
S
S
E
A
D
Q
Q
D
L
Site 48
S358
L
L
Q
A
K
V
A
S
L
T
L
H
N
K
E
Site 49
T360
Q
A
K
V
A
S
L
T
L
H
N
K
E
L
Q
Site 50
S374
Q
D
K
L
Q
A
K
S
P
K
E
A
E
A
D
Site 51
S383
K
E
A
E
A
D
L
S
F
D
S
Y
H
S
T
Site 52
S386
E
A
D
L
S
F
D
S
Y
H
S
T
Q
T
D
Site 53
Y387
A
D
L
S
F
D
S
Y
H
S
T
Q
T
D
L
Site 54
S389
L
S
F
D
S
Y
H
S
T
Q
T
D
L
G
P
Site 55
T390
S
F
D
S
Y
H
S
T
Q
T
D
L
G
P
S
Site 56
S405
L
G
K
P
G
E
T
S
P
P
D
S
K
S
S
Site 57
S409
G
E
T
S
P
P
D
S
K
S
S
P
S
V
L
Site 58
S411
T
S
P
P
D
S
K
S
S
P
S
V
L
I
H
Site 59
S412
S
P
P
D
S
K
S
S
P
S
V
L
I
H
S
Site 60
S414
P
D
S
K
S
S
P
S
V
L
I
H
S
L
G
Site 61
S419
S
P
S
V
L
I
H
S
L
G
K
S
T
T
D
Site 62
S423
L
I
H
S
L
G
K
S
T
T
D
N
D
V
R
Site 63
T425
H
S
L
G
K
S
T
T
D
N
D
V
R
I
Q
Site 64
S447
D
L
Q
K
R
L
E
S
S
E
A
E
R
K
Q
Site 65
S461
Q
L
Q
V
E
L
Q
S
R
R
A
E
L
V
C
Site 66
S475
C
L
N
N
T
E
I
S
E
N
S
S
D
L
S
Site 67
S479
T
E
I
S
E
N
S
S
D
L
S
Q
K
L
K
Site 68
S482
S
E
N
S
S
D
L
S
Q
K
L
K
E
T
Q
Site 69
S490
Q
K
L
K
E
T
Q
S
K
Y
E
E
A
M
K
Site 70
Y492
L
K
E
T
Q
S
K
Y
E
E
A
M
K
E
V
Site 71
S512
Q
M
K
L
G
L
V
S
P
E
S
M
D
N
Y
Site 72
S515
L
G
L
V
S
P
E
S
M
D
N
Y
S
H
F
Site 73
Y519
S
P
E
S
M
D
N
Y
S
H
F
H
E
L
R
Site 74
S520
P
E
S
M
D
N
Y
S
H
F
H
E
L
R
V
Site 75
T528
H
F
H
E
L
R
V
T
E
E
E
I
N
V
L
Site 76
S546
L
Q
N
A
L
E
E
S
E
R
N
K
E
K
V
Site 77
Y576
I
K
P
P
V
E
E
Y
E
E
M
K
S
S
Y
Site 78
S581
E
E
Y
E
E
M
K
S
S
Y
C
S
V
I
E
Site 79
S582
E
Y
E
E
M
K
S
S
Y
C
S
V
I
E
N
Site 80
Y583
Y
E
E
M
K
S
S
Y
C
S
V
I
E
N
M
Site 81
Y601
K
A
F
L
F
E
K
Y
Q
E
A
Q
E
E
I
Site 82
T614
E
I
M
K
L
K
D
T
L
K
S
Q
M
T
Q
Site 83
S617
K
L
K
D
T
L
K
S
Q
M
T
Q
E
A
S
Site 84
T620
D
T
L
K
S
Q
M
T
Q
E
A
S
D
E
A
Site 85
S624
S
Q
M
T
Q
E
A
S
D
E
A
E
D
M
K
Site 86
S646
D
E
L
N
K
Q
V
S
E
L
S
Q
L
Y
K
Site 87
S649
N
K
Q
V
S
E
L
S
Q
L
Y
K
E
A
Q
Site 88
Y662
A
Q
A
E
L
E
D
Y
R
K
R
K
S
L
E
Site 89
S667
E
D
Y
R
K
R
K
S
L
E
D
V
T
A
E
Site 90
T672
R
K
S
L
E
D
V
T
A
E
Y
I
H
K
A
Site 91
Y675
L
E
D
V
T
A
E
Y
I
H
K
A
E
H
E
Site 92
S700
A
K
A
E
D
A
L
S
E
M
K
S
Q
Y
S
Site 93
S704
D
A
L
S
E
M
K
S
Q
Y
S
K
V
L
N
Site 94
T714
S
K
V
L
N
E
L
T
Q
L
K
Q
L
V
D
Site 95
S727
V
D
A
Q
K
E
N
S
V
S
I
T
E
H
L
Site 96
S729
A
Q
K
E
N
S
V
S
I
T
E
H
L
Q
V
Site 97
T731
K
E
N
S
V
S
I
T
E
H
L
Q
V
I
T
Site 98
T739
E
H
L
Q
V
I
T
T
L
R
T
A
A
K
E
Site 99
S752
K
E
M
E
E
K
I
S
N
L
K
E
H
L
A
Site 100
S760
N
L
K
E
H
L
A
S
K
E
V
E
V
A
K
Site 101
S787
T
D
A
M
V
P
R
S
S
Y
E
K
L
Q
S
Site 102
S788
D
A
M
V
P
R
S
S
Y
E
K
L
Q
S
S
Site 103
Y789
A
M
V
P
R
S
S
Y
E
K
L
Q
S
S
L
Site 104
S794
S
S
Y
E
K
L
Q
S
S
L
E
S
E
V
S
Site 105
S795
S
Y
E
K
L
Q
S
S
L
E
S
E
V
S
V
Site 106
S798
K
L
Q
S
S
L
E
S
E
V
S
V
L
A
S
Site 107
S801
S
S
L
E
S
E
V
S
V
L
A
S
K
L
K
Site 108
S805
S
E
V
S
V
L
A
S
K
L
K
E
S
V
K
Site 109
S810
L
A
S
K
L
K
E
S
V
K
E
K
E
K
V
Site 110
T840
R
E
K
E
N
I
Q
T
L
L
K
S
K
E
Q
Site 111
S844
N
I
Q
T
L
L
K
S
K
E
Q
E
V
N
E
Site 112
Y869
E
L
A
E
M
K
R
Y
A
E
S
S
S
K
L
Site 113
S872
E
M
K
R
Y
A
E
S
S
S
K
L
E
E
D
Site 114
S873
M
K
R
Y
A
E
S
S
S
K
L
E
E
D
K
Site 115
S900
K
L
K
E
A
L
N
S
L
S
Q
L
S
Y
S
Site 116
S902
K
E
A
L
N
S
L
S
Q
L
S
Y
S
T
S
Site 117
S905
L
N
S
L
S
Q
L
S
Y
S
T
S
S
S
K
Site 118
Y906
N
S
L
S
Q
L
S
Y
S
T
S
S
S
K
R
Site 119
S907
S
L
S
Q
L
S
Y
S
T
S
S
S
K
R
Q
Site 120
T908
L
S
Q
L
S
Y
S
T
S
S
S
K
R
Q
S
Site 121
S909
S
Q
L
S
Y
S
T
S
S
S
K
R
Q
S
Q
Site 122
S910
Q
L
S
Y
S
T
S
S
S
K
R
Q
S
Q
Q
Site 123
S911
L
S
Y
S
T
S
S
S
K
R
Q
S
Q
Q
L
Site 124
S915
T
S
S
S
K
R
Q
S
Q
Q
L
E
A
L
Q
Site 125
Y952
V
Y
R
M
H
L
L
Y
A
V
Q
G
Q
M
D
Site 126
T971
K
V
L
K
Q
I
L
T
M
C
K
N
Q
S
Q
Site 127
S977
L
T
M
C
K
N
Q
S
Q
K
K
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation