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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PKD2L1
Full Name:
Polycystic kidney disease 2-like 1 protein
Alias:
Type:
Mass (Da):
91982
Number AA:
805
UniProt ID:
Q9P0L9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
N
A
V
G
S
P
E
G
Q
E
L
Q
Site 2
S17
Q
E
L
Q
K
L
G
S
G
A
W
D
N
P
A
Site 3
Y25
G
A
W
D
N
P
A
Y
S
G
P
P
S
P
H
Site 4
S26
A
W
D
N
P
A
Y
S
G
P
P
S
P
H
G
Site 5
S30
P
A
Y
S
G
P
P
S
P
H
G
T
L
R
V
Site 6
T34
G
P
P
S
P
H
G
T
L
R
V
C
T
I
S
Site 7
T60
P
E
D
E
P
Q
E
T
A
Y
R
T
Q
V
S
Site 8
Y62
D
E
P
Q
E
T
A
Y
R
T
Q
V
S
S
C
Site 9
T64
P
Q
E
T
A
Y
R
T
Q
V
S
S
C
C
L
Site 10
T83
G
I
R
G
L
W
G
T
T
L
T
E
N
T
A
Site 11
Y96
T
A
E
N
R
E
L
Y
I
K
T
T
L
R
E
Site 12
T99
N
R
E
L
Y
I
K
T
T
L
R
E
L
L
V
Site 13
T100
R
E
L
Y
I
K
T
T
L
R
E
L
L
V
Y
Site 14
S124
L
T
Y
G
M
T
S
S
S
A
Y
Y
Y
T
K
Site 15
Y128
M
T
S
S
S
A
Y
Y
Y
T
K
V
M
S
E
Site 16
Y129
T
S
S
S
A
Y
Y
Y
T
K
V
M
S
E
L
Site 17
T130
S
S
S
A
Y
Y
Y
T
K
V
M
S
E
L
F
Site 18
T140
M
S
E
L
F
L
H
T
P
S
D
T
G
V
S
Site 19
S142
E
L
F
L
H
T
P
S
D
T
G
V
S
F
Q
Site 20
S147
T
P
S
D
T
G
V
S
F
Q
A
I
S
S
M
Site 21
Y170
G
P
L
L
D
S
L
Y
W
T
K
W
Y
N
N
Site 22
Y189
H
G
S
H
S
F
I
Y
Y
E
N
M
L
L
G
Site 23
S209
Q
L
K
V
R
N
D
S
C
V
V
H
E
D
F
Site 24
S222
D
F
R
E
D
I
L
S
C
Y
D
V
Y
S
P
Site 25
Y224
R
E
D
I
L
S
C
Y
D
V
Y
S
P
D
K
Site 26
Y227
I
L
S
C
Y
D
V
Y
S
P
D
K
E
E
Q
Site 27
S228
L
S
C
Y
D
V
Y
S
P
D
K
E
E
Q
L
Site 28
S249
G
T
A
W
T
Y
H
S
Q
D
E
L
G
G
F
Site 29
T263
F
S
H
W
G
R
L
T
S
Y
S
G
G
G
Y
Site 30
S264
S
H
W
G
R
L
T
S
Y
S
G
G
G
Y
Y
Site 31
Y265
H
W
G
R
L
T
S
Y
S
G
G
G
Y
Y
L
Site 32
S266
W
G
R
L
T
S
Y
S
G
G
G
Y
Y
L
D
Site 33
Y270
T
S
Y
S
G
G
G
Y
Y
L
D
L
P
G
S
Site 34
Y271
S
Y
S
G
G
G
Y
Y
L
D
L
P
G
S
R
Site 35
S277
Y
Y
L
D
L
P
G
S
R
Q
G
S
A
E
A
Site 36
S281
L
P
G
S
R
Q
G
S
A
E
A
L
R
A
L
Site 37
S333
A
T
G
G
A
I
P
S
W
Q
I
R
T
V
K
Site 38
Y344
R
T
V
K
L
I
R
Y
V
S
N
W
D
F
F
Site 39
S383
I
H
R
L
R
Y
L
S
S
I
W
N
I
L
D
Site 40
S384
H
R
L
R
Y
L
S
S
I
W
N
I
L
D
L
Site 41
T424
K
L
L
Q
Q
P
N
T
Y
A
D
F
E
F
L
Site 42
T462
K
Y
I
S
F
N
K
T
M
T
Q
L
S
S
T
Site 43
T469
T
M
T
Q
L
S
S
T
L
A
R
C
A
K
D
Site 44
Y564
L
A
I
I
N
D
T
Y
S
E
V
K
E
E
L
Site 45
S565
A
I
I
N
D
T
Y
S
E
V
K
E
E
L
A
Site 46
S581
Q
K
D
E
L
Q
L
S
D
L
L
K
Q
G
Y
Site 47
Y588
S
D
L
L
K
Q
G
Y
N
K
T
L
L
R
L
Site 48
T591
L
K
Q
G
Y
N
K
T
L
L
R
L
R
L
R
Site 49
S603
R
L
R
K
E
R
V
S
D
V
Q
K
V
L
Q
Site 50
T622
E
I
Q
F
E
D
F
T
N
T
L
R
E
L
G
Site 51
T624
Q
F
E
D
F
T
N
T
L
R
E
L
G
H
A
Site 52
T636
G
H
A
E
H
E
I
T
E
L
T
A
T
F
T
Site 53
T641
E
I
T
E
L
T
A
T
F
T
K
F
D
R
D
Site 54
T674
E
E
R
V
A
L
N
T
E
I
E
K
L
G
R
Site 55
S682
E
I
E
K
L
G
R
S
I
V
S
S
P
Q
G
Site 56
S686
L
G
R
S
I
V
S
S
P
Q
G
K
S
G
P
Site 57
S691
V
S
S
P
Q
G
K
S
G
P
E
A
A
R
A
Site 58
S703
A
R
A
G
G
W
V
S
G
E
E
F
Y
M
L
Site 59
T711
G
E
E
F
Y
M
L
T
R
R
V
L
Q
L
E
Site 60
S747
R
K
G
W
L
A
P
S
P
G
V
K
E
Q
A
Site 61
T766
P
Q
P
A
P
A
V
T
P
D
P
W
G
V
Q
Site 62
S778
G
V
Q
G
G
Q
E
S
E
V
P
Y
K
R
E
Site 63
Y782
G
Q
E
S
E
V
P
Y
K
R
E
E
E
A
L
Site 64
S795
A
L
E
E
R
R
L
S
R
G
E
I
P
T
L
Site 65
T801
L
S
R
G
E
I
P
T
L
Q
R
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation