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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
H2AFY2
Full Name:
Core histone macro-H2A.2
Alias:
Core histone macroH2A2.2; H2A histone family, member Y2; H2AW; Histone macroH2A2; MACROH2A2; MH2A2
Type:
DNA binding protein
Mass (Da):
40058
Number AA:
372
UniProt ID:
Q9P0M6
International Prot ID:
IPI00220994
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0001740
GO:0000786
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0016568
GO:0007549
GO:0006334
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
R
S
G
K
K
K
M
S
K
L
S
R
S
A
R
Site 2
S14
K
K
K
M
S
K
L
S
R
S
A
R
A
G
V
Site 3
S16
K
M
S
K
L
S
R
S
A
R
A
G
V
I
F
Site 4
Y31
P
V
G
R
L
M
R
Y
L
K
K
G
T
F
K
Site 5
T36
M
R
Y
L
K
K
G
T
F
K
Y
R
I
S
V
Site 6
Y39
L
K
K
G
T
F
K
Y
R
I
S
V
G
A
P
Site 7
Y55
Y
M
A
A
V
I
E
Y
L
A
A
E
I
L
E
Site 8
T120
L
L
A
K
K
R
G
T
K
G
K
S
E
T
I
Site 9
S124
K
R
G
T
K
G
K
S
E
T
I
L
S
P
P
Site 10
S129
G
K
S
E
T
I
L
S
P
P
P
E
K
R
G
Site 11
T140
E
K
R
G
R
K
A
T
S
G
K
K
G
G
K
Site 12
S141
K
R
G
R
K
A
T
S
G
K
K
G
G
K
K
Site 13
S149
G
K
K
G
G
K
K
S
K
A
A
K
P
R
T
Site 14
T156
S
K
A
A
K
P
R
T
S
K
K
S
K
P
K
Site 15
S157
K
A
A
K
P
R
T
S
K
K
S
K
P
K
D
Site 16
S160
K
P
R
T
S
K
K
S
K
P
K
D
S
D
K
Site 17
S165
K
K
S
K
P
K
D
S
D
K
E
G
T
S
N
Site 18
S171
D
S
D
K
E
G
T
S
N
S
T
S
E
D
G
Site 19
S173
D
K
E
G
T
S
N
S
T
S
E
D
G
P
G
Site 20
S175
E
G
T
S
N
S
T
S
E
D
G
P
G
D
G
Site 21
T184
D
G
P
G
D
G
F
T
I
L
S
S
K
S
L
Site 22
S198
L
V
L
G
Q
K
L
S
L
T
Q
S
D
I
S
Site 23
T200
L
G
Q
K
L
S
L
T
Q
S
D
I
S
H
I
Site 24
S202
Q
K
L
S
L
T
Q
S
D
I
S
H
I
G
S
Site 25
S205
S
L
T
Q
S
D
I
S
H
I
G
S
M
R
V
Site 26
T220
E
G
I
V
H
P
T
T
A
E
I
D
L
K
E
Site 27
T244
G
G
K
E
F
L
E
T
V
K
E
L
R
K
S
Site 28
S251
T
V
K
E
L
R
K
S
Q
G
P
L
E
V
A
Site 29
S263
E
V
A
E
A
A
V
S
Q
S
S
G
L
A
A
Site 30
S308
A
E
D
K
K
L
K
S
V
A
F
P
P
F
P
Site 31
S316
V
A
F
P
P
F
P
S
G
R
N
C
F
P
K
Site 32
S341
I
S
A
H
F
D
D
S
S
A
S
S
L
K
N
Site 33
S342
S
A
H
F
D
D
S
S
A
S
S
L
K
N
V
Site 34
S345
F
D
D
S
S
A
S
S
L
K
N
V
Y
F
L
Site 35
Y362
D
S
E
S
I
G
I
Y
V
Q
E
M
A
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation