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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBC1D7
Full Name:
TBC1 domain family member 7
Alias:
PIG51; TBCD7
Type:
GTPase activating protein, Rab
Mass (Da):
33972
Number AA:
293
UniProt ID:
Q9P0N9
International Prot ID:
IPI00009425
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005097
PhosphoSite+
KinaseNET
Biological Process:
GO:0032313
Phosida
TranscriptoNet
STRING
Kinexus Products
TBC1 domain family member 7 Y14 phosphosite-specific antibody AB-PN540#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN540#TBC1 domain family member 7 (S11-V17, human) pY14 phosphopeptide - Powder PE-04AEE99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AEE99
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
Q
R
N
F
R
S
V
Y
Y
E
K
V
G
F
R
Site 2
Y14
R
N
F
R
S
V
Y
Y
E
K
V
G
F
R
G
TBC1 domain family member 7 Y14 phosphosite-specific antibody AB-PN540#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN540#TBC1 domain family member 7 (S11-V17, human) pY14 phosphopeptide - Powder PE-04AEE99#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AEE99
Site 3
S27
R
G
V
E
E
K
K
S
L
E
I
L
L
K
D
Site 4
T39
L
K
D
D
R
L
D
T
E
K
L
C
T
F
S
Site 5
T44
L
D
T
E
K
L
C
T
F
S
Q
R
F
P
L
Site 6
S46
T
E
K
L
C
T
F
S
Q
R
F
P
L
P
S
Site 7
S53
S
Q
R
F
P
L
P
S
M
Y
R
A
L
V
W
Site 8
Y85
M
M
Y
R
K
E
Q
Y
L
D
V
L
H
A
L
Site 9
S99
L
K
V
V
R
F
V
S
D
A
T
P
Q
A
E
Site 10
Y108
A
T
P
Q
A
E
V
Y
L
R
M
Y
Q
L
E
Site 11
Y112
A
E
V
Y
L
R
M
Y
Q
L
E
S
G
K
L
Site 12
S122
E
S
G
K
L
P
R
S
P
S
F
P
L
E
P
Site 13
S124
G
K
L
P
R
S
P
S
F
P
L
E
P
D
D
Site 14
Y152
V
E
D
S
V
D
C
Y
W
I
T
R
R
F
V
Site 15
T164
R
F
V
N
Q
L
N
T
K
Y
R
D
S
L
P
Site 16
Y166
V
N
Q
L
N
T
K
Y
R
D
S
L
P
Q
L
Site 17
S169
L
N
T
K
Y
R
D
S
L
P
Q
L
P
K
A
Site 18
Y180
L
P
K
A
F
E
Q
Y
L
N
L
E
D
G
R
Site 19
T190
L
E
D
G
R
L
L
T
H
L
R
M
C
S
A
Site 20
Y203
S
A
A
P
K
L
P
Y
D
L
W
F
K
R
C
Site 21
S218
F
A
G
C
L
P
E
S
S
L
Q
R
V
W
D
Site 22
S219
A
G
C
L
P
E
S
S
L
Q
R
V
W
D
K
Site 23
S271
E
N
I
P
Q
D
S
S
D
A
I
V
S
K
A
Site 24
S276
D
S
S
D
A
I
V
S
K
A
I
D
L
W
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation