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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DOK5
Full Name:
Docking protein 5
Alias:
Type:
Mass (Da):
35464
Number AA:
306
UniProt ID:
Q9P104
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
N
D
I
V
K
Q
G
Y
V
R
I
R
S
R
R
Site 2
S18
Q
G
Y
V
R
I
R
S
R
R
L
G
I
Y
Q
Site 3
Y24
R
S
R
R
L
G
I
Y
Q
R
C
W
L
V
F
Site 4
S46
P
K
R
L
E
K
F
S
D
E
R
A
A
Y
F
Site 5
Y52
F
S
D
E
R
A
A
Y
F
R
C
Y
H
K
V
Site 6
Y56
R
A
A
Y
F
R
C
Y
H
K
V
T
E
L
N
Site 7
S74
N
V
A
R
L
P
K
S
T
K
K
H
A
I
G
Site 8
Y83
K
K
H
A
I
G
I
Y
F
N
D
D
T
S
K
Site 9
T91
F
N
D
D
T
S
K
T
F
A
C
E
S
D
L
Site 10
S96
S
K
T
F
A
C
E
S
D
L
E
A
D
E
W
Site 11
S120
G
T
R
I
N
D
I
S
L
G
E
P
D
L
L
Site 12
S136
T
G
V
E
R
E
Q
S
E
R
F
N
V
Y
L
Site 13
Y142
Q
S
E
R
F
N
V
Y
L
M
P
S
P
N
L
Site 14
S146
F
N
V
Y
L
M
P
S
P
N
L
D
V
H
G
Site 15
S178
N
P
R
V
K
L
I
S
W
P
L
S
A
L
R
Site 16
S182
K
L
I
S
W
P
L
S
A
L
R
R
Y
G
R
Site 17
Y187
P
L
S
A
L
R
R
Y
G
R
D
T
T
W
F
Site 18
T191
L
R
R
Y
G
R
D
T
T
W
F
T
F
E
A
Site 19
T192
R
R
Y
G
R
D
T
T
W
F
T
F
E
A
G
Site 20
T195
G
R
D
T
T
W
F
T
F
E
A
G
R
M
C
Site 21
T213
E
G
L
F
I
F
Q
T
R
D
G
E
A
I
Y
Site 22
Y220
T
R
D
G
E
A
I
Y
Q
K
V
H
S
A
A
Site 23
S240
Q
H
E
R
L
L
Q
S
V
K
N
S
M
L
Q
Site 24
S244
L
L
Q
S
V
K
N
S
M
L
Q
M
K
M
S
Site 25
S251
S
M
L
Q
M
K
M
S
E
R
A
A
S
L
S
Site 26
S256
K
M
S
E
R
A
A
S
L
S
T
M
V
P
L
Site 27
S258
S
E
R
A
A
S
L
S
T
M
V
P
L
P
R
Site 28
T259
E
R
A
A
S
L
S
T
M
V
P
L
P
R
S
Site 29
Y268
V
P
L
P
R
S
A
Y
W
Q
H
I
T
R
Q
Site 30
S277
Q
H
I
T
R
Q
H
S
T
G
Q
L
Y
R
L
Site 31
S288
L
Y
R
L
Q
D
V
S
S
P
L
K
L
H
R
Site 32
S289
Y
R
L
Q
D
V
S
S
P
L
K
L
H
R
T
Site 33
T296
S
P
L
K
L
H
R
T
E
T
F
P
A
Y
R
Site 34
T298
L
K
L
H
R
T
E
T
F
P
A
Y
R
S
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation