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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C14orf174
Full Name:
SAM domain-containing protein C14orf174
Alias:
chromosome 14 open reading frame 174; CN174; FAM15A; FLJ35963; MGC132494; MGC132496
Type:
Mass (Da):
77150
Number AA:
UniProt ID:
Q9P1V8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
A
E
V
P
E
D
Y
D
S
G
P
D
E
D
Site 2
S10
E
V
P
E
D
Y
D
S
G
P
D
E
D
G
E
Site 3
Y32
L
P
G
L
H
K
L
Y
E
N
A
E
P
D
T
Site 4
T39
Y
E
N
A
E
P
D
T
M
A
K
A
D
S
K
Site 5
S45
D
T
M
A
K
A
D
S
K
L
P
A
E
I
Y
Site 6
Y52
S
K
L
P
A
E
I
Y
Q
E
P
Q
P
E
T
Site 7
S71
F
K
E
G
E
P
D
S
A
K
N
V
Q
L
K
Site 8
S91
Q
E
G
I
A
K
E
S
K
R
D
V
P
S
E
Site 9
S97
E
S
K
R
D
V
P
S
E
T
E
P
G
I
H
Site 10
S109
G
I
H
Q
E
V
K
S
E
T
S
R
E
M
G
Site 11
T129
L
E
A
P
M
D
E
T
H
K
E
S
D
L
E
Site 12
T157
F
L
E
S
A
M
E
T
D
P
D
P
V
P
P
Site 13
T165
D
P
D
P
V
P
P
T
E
T
M
S
E
V
S
Site 14
S169
V
P
P
T
E
T
M
S
E
V
S
G
A
T
V
Site 15
S196
E
P
G
V
P
E
E
S
L
R
V
Q
H
E
E
Site 16
S218
Q
T
K
Q
D
F
P
S
E
K
L
G
E
S
L
Site 17
S224
P
S
E
K
L
G
E
S
L
E
E
T
D
L
Q
Site 18
T228
L
G
E
S
L
E
E
T
D
L
Q
P
P
K
M
Site 19
T240
P
K
M
T
K
P
E
T
P
E
E
T
Q
R
E
Site 20
T244
K
P
E
T
P
E
E
T
Q
R
E
S
T
E
K
Site 21
S248
P
E
E
T
Q
R
E
S
T
E
K
K
R
T
E
Site 22
T249
E
E
T
Q
R
E
S
T
E
K
K
R
T
E
P
Site 23
T254
E
S
T
E
K
K
R
T
E
P
P
E
Q
A
R
Site 24
S272
L
E
K
E
P
R
K
S
S
E
E
A
G
L
E
Site 25
S273
E
K
E
P
R
K
S
S
E
E
A
G
L
E
P
Site 26
T297
E
E
M
Q
R
K
A
T
E
E
K
G
T
E
L
Site 27
T302
K
A
T
E
E
K
G
T
E
L
P
E
R
T
K
Site 28
S320
P
D
H
K
P
R
K
S
T
D
E
N
V
P
E
Site 29
T321
D
H
K
P
R
K
S
T
D
E
N
V
P
E
P
Site 30
T344
P
E
E
E
S
R
K
T
N
E
E
T
I
L
E
Site 31
S360
S
E
M
M
K
P
E
S
P
E
E
I
R
K
S
Site 32
S367
S
P
E
E
I
R
K
S
N
E
K
K
N
P
Q
Site 33
T397
Q
V
E
E
K
T
Q
T
K
P
T
E
K
I
L
Site 34
T410
I
L
E
L
P
D
E
T
K
P
R
E
T
H
V
Site 35
T415
D
E
T
K
P
R
E
T
H
V
E
F
S
K
E
Site 36
S430
D
R
P
E
P
I
K
S
K
Y
S
V
G
N
D
Site 37
Y432
P
E
P
I
K
S
K
Y
S
V
G
N
D
E
L
Site 38
S450
E
P
K
R
G
K
L
S
L
S
D
K
F
R
K
Site 39
S452
K
R
G
K
L
S
L
S
D
K
F
R
K
E
Y
Site 40
Y459
S
D
K
F
R
K
E
Y
Y
A
L
G
S
L
R
Site 41
Y460
D
K
F
R
K
E
Y
Y
A
L
G
S
L
R
E
Site 42
S464
K
E
Y
Y
A
L
G
S
L
R
E
S
E
E
S
Site 43
S468
A
L
G
S
L
R
E
S
E
E
S
I
G
T
H
Site 44
S471
S
L
R
E
S
E
E
S
I
G
T
H
Y
E
F
Site 45
T474
E
S
E
E
S
I
G
T
H
Y
E
F
L
Q
P
Site 46
Y476
E
E
S
I
G
T
H
Y
E
F
L
Q
P
L
Q
Site 47
S489
L
Q
K
L
L
N
V
S
E
E
C
S
Y
S
D
Site 48
S493
L
N
V
S
E
E
C
S
Y
S
D
P
S
E
S
Site 49
Y494
N
V
S
E
E
C
S
Y
S
D
P
S
E
S
Q
Site 50
S495
V
S
E
E
C
S
Y
S
D
P
S
E
S
Q
T
Site 51
S498
E
C
S
Y
S
D
P
S
E
S
Q
T
E
L
S
Site 52
S500
S
Y
S
D
P
S
E
S
Q
T
E
L
S
E
F
Site 53
T502
S
D
P
S
E
S
Q
T
E
L
S
E
F
V
H
Site 54
S505
S
E
S
Q
T
E
L
S
E
F
V
H
E
K
E
Site 55
S517
E
K
E
V
V
D
L
S
Q
E
L
K
E
R
V
Site 56
S525
Q
E
L
K
E
R
V
S
E
D
D
E
T
Q
P
Site 57
T530
R
V
S
E
D
D
E
T
Q
P
E
K
G
T
E
Site 58
S555
E
E
V
A
E
W
I
S
Q
L
G
F
P
Q
Y
Site 59
Y562
S
Q
L
G
F
P
Q
Y
K
E
C
F
I
T
N
Site 60
T602
M
K
A
I
S
R
H
T
Q
E
L
L
E
I
E
Site 61
S616
E
E
P
L
F
K
R
S
I
S
L
P
Y
R
D
Site 62
S618
P
L
F
K
R
S
I
S
L
P
Y
R
D
I
I
Site 63
Y628
Y
R
D
I
I
G
L
Y
L
E
Q
K
G
H
T
Site 64
S639
K
G
H
T
G
I
K
S
D
S
L
T
L
S
E
Site 65
S641
H
T
G
I
K
S
D
S
L
T
L
S
E
F
V
Site 66
T643
G
I
K
S
D
S
L
T
L
S
E
F
V
K
A
Site 67
S645
K
S
D
S
L
T
L
S
E
F
V
K
A
A
G
Site 68
Y656
K
A
A
G
L
Q
D
Y
A
P
E
I
T
A
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation