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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Pim2
Full Name:
Serine/threonine-protein kinase pim-2
Alias:
EC 2.7.11.1; Pim-2h
Type:
Protein-serine kinase, CAMK group, PIM family
Mass (Da):
34190
Number AA:
311
UniProt ID:
Q9P1W9
International Prot ID:
IPI00332692
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004674
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0008283
GO:0007140
Phosida
TranscriptoNet
STRING
Kinexus Products
Serine/threonine-protein kinase Pim-2 pan-specific antibody AB-NK288-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NK288-1#Serine/threonine-protein kinase Pim-2 pan-specific antibody AB-NK288-2#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NK288-2#Serine/threonine-protein kinase Pim-2 T195 phosphosite-specific antibody AB-PK761#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PK761#RPS6 (230-238) KinSub - 40S ribosomal protein S6 (K230-R238, human) peptide; p70S6K protein kinase substrate peptide - Powder PE-01ADQ95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01ADQ95#Serine/threonine-protein kinase Pim-2 (P20-G35, human) peptide - Powder PE-01BER85#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BER85#Serine/threonine-protein kinase Pim-2 (L282-G300, human) peptide - Powder PE-01BES85#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BES85#Serine/threonine-protein kinase Pim-2 (E192-D198, human) pT195 phosphopeptide - Powder PE-04AOP95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AOP95
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
G
P
P
A
P
P
G
T
P
T
P
P
P
G
G
Site 2
T17
P
A
P
P
G
T
P
T
P
P
P
G
G
K
D
Site 3
Y32
R
E
A
F
E
A
E
Y
R
L
G
P
L
L
G
Site 4
S72
R
N
R
V
L
G
W
S
P
L
S
D
S
V
T
Site 5
Y128
P
A
Q
D
L
F
D
Y
I
T
E
K
G
P
L
Site 6
T130
Q
D
L
F
D
Y
I
T
E
K
G
P
L
G
E
Site 7
S140
G
P
L
G
E
G
P
S
R
C
F
F
G
Q
V
Site 8
S185
A
K
L
I
D
F
G
S
G
A
L
L
H
D
E
Site 9
Y194
A
L
L
H
D
E
P
Y
T
D
F
D
G
T
R
Site 10
T195
L
L
H
D
E
P
Y
T
D
F
D
G
T
R
V
Serine/threonine-protein kinase Pim-2 T195 phosphosite-specific antibody AB-PK761#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PK761#Serine/threonine-protein kinase Pim-2 (E192-D198, human) pT195 phosphopeptide - Powder PE-04AOP95#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-04AOP95
Site 11
T200
P
Y
T
D
F
D
G
T
R
V
Y
S
P
P
E
Site 12
Y203
D
F
D
G
T
R
V
Y
S
P
P
E
W
I
S
Site 13
S204
F
D
G
T
R
V
Y
S
P
P
E
W
I
S
R
Site 14
Y214
E
W
I
S
R
H
Q
Y
H
A
L
P
A
T
V
Site 15
S272
R
C
L
A
P
K
P
S
S
R
P
S
L
E
E
Site 16
S273
C
L
A
P
K
P
S
S
R
P
S
L
E
E
I
Site 17
S276
P
K
P
S
S
R
P
S
L
E
E
I
L
L
D
Site 18
T288
L
L
D
P
W
M
Q
T
P
A
E
D
V
P
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation