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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1529
Full Name:
Uncharacterized protein C9orf174
Alias:
LOC57653
Type:
Uncharacterized
Mass (Da):
198123
Number AA:
1708
UniProt ID:
Q9P1Z9
International Prot ID:
IPI00292836
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T72
L
I
A
R
I
D
R
T
I
M
Q
S
G
Y
E
Site 2
Y78
R
T
I
M
Q
S
G
Y
E
G
A
D
M
G
F
Site 3
T112
S
F
C
H
I
L
I
T
N
H
R
E
K
K
L
Site 4
Y125
K
L
Q
Q
S
T
K
Y
W
C
L
N
Q
S
A
Site 5
S134
C
L
N
Q
S
A
E
S
L
R
I
C
A
M
R
Site 6
S153
R
P
P
A
R
V
Q
S
S
S
E
E
L
E
L
Site 7
S155
P
A
R
V
Q
S
S
S
E
E
L
E
L
R
H
Site 8
S164
E
L
E
L
R
H
Q
S
L
D
A
F
P
G
R
Site 9
S186
Q
P
A
A
K
M
S
S
V
G
K
V
T
Q
V
Site 10
T191
M
S
S
V
G
K
V
T
Q
V
P
N
G
K
A
Site 11
S212
A
E
V
Q
L
V
H
S
L
A
A
T
R
K
R
Site 12
T216
L
V
H
S
L
A
A
T
R
K
R
A
A
E
R
Site 13
S224
R
K
R
A
A
E
R
S
V
T
L
K
S
G
R
Site 14
T226
R
A
A
E
R
S
V
T
L
K
S
G
R
I
P
Site 15
S229
E
R
S
V
T
L
K
S
G
R
I
P
M
M
K
Site 16
T240
P
M
M
K
K
V
E
T
P
E
G
E
V
M
S
Site 17
S247
T
P
E
G
E
V
M
S
P
R
Q
Q
K
W
M
Site 18
S283
K
R
E
K
A
R
E
S
E
N
T
I
A
A
R
Site 19
T286
K
A
R
E
S
E
N
T
I
A
A
R
E
V
R
Site 20
T298
E
V
R
G
L
M
D
T
I
V
P
E
K
I
S
Site 21
T308
P
E
K
I
S
T
S
T
F
Q
R
Q
A
E
H
Site 22
S319
Q
A
E
H
K
R
K
S
Y
E
S
A
L
A
S
Site 23
Y320
A
E
H
K
R
K
S
Y
E
S
A
L
A
S
F
Site 24
S322
H
K
R
K
S
Y
E
S
A
L
A
S
F
Q
E
Site 25
S326
S
Y
E
S
A
L
A
S
F
Q
E
E
I
A
Q
Site 26
T354
G
L
F
L
K
K
L
T
E
S
D
E
E
M
N
Site 27
S356
L
K
K
L
T
E
S
D
E
E
M
N
R
L
F
Site 28
Y376
N
D
T
N
L
E
D
Y
T
I
Q
A
L
L
E
Site 29
T377
D
T
N
L
E
D
Y
T
I
Q
A
L
L
E
L
Site 30
S408
E
L
D
E
A
L
H
S
L
E
F
S
R
T
D
Site 31
S412
A
L
H
S
L
E
F
S
R
T
D
K
L
K
S
Site 32
T414
H
S
L
E
F
S
R
T
D
K
L
K
S
V
L
Site 33
S419
S
R
T
D
K
L
K
S
V
L
K
K
Y
A
E
Site 34
Y424
L
K
S
V
L
K
K
Y
A
E
V
I
E
K
T
Site 35
Y433
E
V
I
E
K
T
S
Y
L
M
R
P
E
V
Y
Site 36
Y452
E
E
A
M
V
M
N
Y
A
L
L
G
N
R
K
Site 37
S479
T
L
Q
Q
E
L
D
S
R
H
R
W
Q
G
L
Site 38
S501
K
K
E
A
L
L
Q
S
F
S
E
F
M
A
S
Site 39
S503
E
A
L
L
Q
S
F
S
E
F
M
A
S
E
S
Site 40
S508
S
F
S
E
F
M
A
S
E
S
I
H
T
P
P
Site 41
T513
M
A
S
E
S
I
H
T
P
P
A
V
T
K
E
Site 42
T527
E
L
E
V
M
L
K
T
Q
N
V
L
Q
Q
R
Site 43
S549
I
C
D
L
L
P
P
S
Y
S
K
T
Q
L
T
Site 44
S551
D
L
L
P
P
S
Y
S
K
T
Q
L
T
E
W
Site 45
T553
L
P
P
S
Y
S
K
T
Q
L
T
E
W
H
S
Site 46
T556
S
Y
S
K
T
Q
L
T
E
W
H
S
S
L
N
Site 47
S560
T
Q
L
T
E
W
H
S
S
L
N
S
L
N
K
Site 48
S561
Q
L
T
E
W
H
S
S
L
N
S
L
N
K
E
Site 49
S564
E
W
H
S
S
L
N
S
L
N
K
E
L
D
T
Site 50
Y572
L
N
K
E
L
D
T
Y
H
V
D
C
M
M
R
Site 51
Y584
M
M
R
I
R
L
L
Y
E
K
T
W
Q
E
C
Site 52
T615
F
T
E
E
E
A
E
T
L
V
N
Q
F
F
F
Site 53
S642
D
L
E
L
L
D
K
S
F
E
T
L
A
D
Q
Site 54
T650
F
E
T
L
A
D
Q
T
E
W
Q
S
S
H
L
Site 55
Y660
Q
S
S
H
L
F
K
Y
F
Q
E
V
V
Q
L
Site 56
S694
E
Q
H
R
Q
K
H
S
L
E
S
Q
V
Q
E
Site 57
S697
R
Q
K
H
S
L
E
S
Q
V
Q
E
A
H
L
Site 58
S715
L
D
Q
L
R
Q
Q
S
D
K
E
T
L
A
F
Site 59
T719
R
Q
Q
S
D
K
E
T
L
A
F
H
L
E
K
Site 60
Y730
H
L
E
K
V
K
D
Y
L
K
N
M
K
S
R
Site 61
Y738
L
K
N
M
K
S
R
Y
E
C
F
H
T
L
L
Site 62
T743
S
R
Y
E
C
F
H
T
L
L
T
K
E
V
M
Site 63
Y752
L
T
K
E
V
M
E
Y
P
A
I
M
L
K
E
Site 64
S762
I
M
L
K
E
L
N
S
Y
S
S
A
L
S
Q
Site 65
Y763
M
L
K
E
L
N
S
Y
S
S
A
L
S
Q
Y
Site 66
S764
L
K
E
L
N
S
Y
S
S
A
L
S
Q
Y
F
Site 67
S768
N
S
Y
S
S
A
L
S
Q
Y
F
F
V
R
E
Site 68
S799
P
E
A
H
E
K
P
S
Q
K
R
V
K
K
L
Site 69
S812
K
L
R
K
K
Q
G
S
K
E
D
M
T
R
S
Site 70
T817
Q
G
S
K
E
D
M
T
R
S
E
E
S
I
S
Site 71
S819
S
K
E
D
M
T
R
S
E
E
S
I
S
S
G
Site 72
S822
D
M
T
R
S
E
E
S
I
S
S
G
T
S
T
Site 73
S824
T
R
S
E
E
S
I
S
S
G
T
S
T
A
R
Site 74
S825
R
S
E
E
S
I
S
S
G
T
S
T
A
R
S
Site 75
S828
E
S
I
S
S
G
T
S
T
A
R
S
V
E
E
Site 76
T829
S
I
S
S
G
T
S
T
A
R
S
V
E
E
V
Site 77
S832
S
G
T
S
T
A
R
S
V
E
E
V
E
E
E
Site 78
S846
E
N
D
Q
E
M
E
S
F
I
T
E
E
V
L
Site 79
T849
Q
E
M
E
S
F
I
T
E
E
V
L
G
Q
Q
Site 80
S859
V
L
G
Q
Q
K
K
S
P
L
H
A
K
M
D
Site 81
S868
L
H
A
K
M
D
E
S
K
E
G
S
I
Q
G
Site 82
S872
M
D
E
S
K
E
G
S
I
Q
G
L
E
E
M
Site 83
S886
M
Q
V
E
R
E
G
S
L
N
P
S
L
N
E
Site 84
S890
R
E
G
S
L
N
P
S
L
N
E
E
N
V
K
Site 85
S936
E
A
Q
E
E
Q
E
S
L
S
V
G
E
E
E
Site 86
S938
Q
E
E
Q
E
S
L
S
V
G
E
E
E
D
K
Site 87
Y953
E
E
G
L
E
E
I
Y
Y
E
D
M
E
S
F
Site 88
Y954
E
G
L
E
E
I
Y
Y
E
D
M
E
S
F
T
Site 89
S959
I
Y
Y
E
D
M
E
S
F
T
I
S
S
G
N
Site 90
S963
D
M
E
S
F
T
I
S
S
G
N
T
Y
F
V
Site 91
S982
E
E
E
H
C
R
K
S
H
S
T
F
S
A
M
Site 92
T994
S
A
M
F
I
N
D
T
S
S
A
K
F
I
E
Site 93
S1025
F
S
E
G
G
N
F
S
P
K
E
I
N
S
L
Site 94
S1031
F
S
P
K
E
I
N
S
L
C
S
R
L
E
K
Site 95
T1094
E
K
I
Q
R
L
L
T
N
L
Q
V
K
I
K
Site 96
S1107
I
K
C
Q
V
A
K
S
N
S
Q
T
N
G
L
Site 97
S1109
C
Q
V
A
K
S
N
S
Q
T
N
G
L
N
F
Site 98
T1111
V
A
K
S
N
S
Q
T
N
G
L
N
F
S
L
Site 99
S1117
Q
T
N
G
L
N
F
S
L
Q
Q
L
Q
N
K
Site 100
T1127
Q
L
Q
N
K
I
K
T
C
Q
E
S
R
G
E
Site 101
T1137
E
S
R
G
E
K
T
T
V
T
T
E
E
L
L
Site 102
T1139
R
G
E
K
T
T
V
T
T
E
E
L
L
S
F
Site 103
S1145
V
T
T
E
E
L
L
S
F
V
Q
T
W
K
E
Site 104
T1149
E
L
L
S
F
V
Q
T
W
K
E
K
L
S
Q
Site 105
Y1160
K
L
S
Q
R
I
Q
Y
L
N
C
S
L
D
R
Site 106
S1164
R
I
Q
Y
L
N
C
S
L
D
R
V
S
M
T
Site 107
T1171
S
L
D
R
V
S
M
T
E
L
V
F
T
N
T
Site 108
T1176
S
M
T
E
L
V
F
T
N
T
I
L
K
D
Q
Site 109
S1187
L
K
D
Q
E
E
D
S
D
I
L
T
S
S
E
Site 110
T1191
E
E
D
S
D
I
L
T
S
S
E
A
L
E
E
Site 111
S1193
D
S
D
I
L
T
S
S
E
A
L
E
E
E
A
Site 112
T1206
E
A
K
L
D
V
V
T
P
E
S
F
T
Q
L
Site 113
S1214
P
E
S
F
T
Q
L
S
R
V
G
K
P
L
I
Site 114
T1238
K
L
L
Q
L
P
N
T
K
W
P
T
H
H
C
Site 115
S1271
S
G
K
K
A
V
P
S
A
S
A
T
S
A
G
Site 116
S1273
K
K
A
V
P
S
A
S
A
T
S
A
G
S
L
Site 117
S1279
A
S
A
T
S
A
G
S
L
Q
T
T
H
P
P
Site 118
T1283
S
A
G
S
L
Q
T
T
H
P
P
L
S
H
S
Site 119
S1288
Q
T
T
H
P
P
L
S
H
S
F
T
P
H
P
Site 120
S1290
T
H
P
P
L
S
H
S
F
T
P
H
P
K
P
Site 121
T1292
P
P
L
S
H
S
F
T
P
H
P
K
P
N
K
Site 122
Y1304
P
N
K
M
E
R
K
Y
R
V
L
G
D
K
P
Site 123
T1335
E
S
S
E
N
L
L
T
V
A
E
E
F
Y
R
Site 124
T1349
R
K
E
K
R
P
V
T
R
P
D
C
M
C
D
Site 125
Y1372
I
S
K
K
I
L
E
Y
Q
S
Q
A
N
K
Y
Site 126
Y1379
Y
Q
S
Q
A
N
K
Y
H
N
S
C
L
I
E
Site 127
S1461
V
H
F
Q
E
M
E
S
L
H
L
S
E
E
E
Site 128
S1465
E
M
E
S
L
H
L
S
E
E
E
R
Q
E
E
Site 129
S1475
E
R
Q
E
E
L
D
S
M
I
R
M
N
K
E
Site 130
S1543
R
R
K
L
A
G
L
S
L
K
E
E
S
E
K
Site 131
S1557
K
P
L
I
E
R
G
S
R
K
W
P
G
I
K
Site 132
T1579
N
K
I
L
L
Q
P
T
S
S
I
S
T
T
K
Site 133
S1580
K
I
L
L
Q
P
T
S
S
I
S
T
T
K
T
Site 134
S1581
I
L
L
Q
P
T
S
S
I
S
T
T
K
T
T
Site 135
S1583
L
Q
P
T
S
S
I
S
T
T
K
T
T
L
G
Site 136
T1585
P
T
S
S
I
S
T
T
K
T
T
L
G
H
L
Site 137
Y1605
R
D
A
V
Y
L
K
Y
L
A
S
F
E
E
E
Site 138
S1608
V
Y
L
K
Y
L
A
S
F
E
E
E
L
K
R
Site 139
T1621
K
R
I
Q
D
D
C
T
S
Q
I
K
E
A
Q
Site 140
S1622
R
I
Q
D
D
C
T
S
Q
I
K
E
A
Q
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation