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Updated November 2019
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Protein Info
Short Name:
KIAA1522
Full Name:
Uncharacterized protein KIAA1522
Alias:
K1522
Type:
Unknown function
Mass (Da):
107095
Number AA:
1035
UniProt ID:
Q9P206
International Prot ID:
IPI00001632
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
G
L
F
K
K
K
G
S
A
K
A
E
N
D
K
Site 2
S31
A
E
N
D
K
H
L
S
V
G
P
G
Q
G
P
Site 3
S40
G
P
G
Q
G
P
G
S
A
V
D
E
H
Q
D
Site 4
S53
Q
D
N
V
F
F
P
S
G
R
P
P
H
L
E
Site 5
T64
P
H
L
E
E
L
H
T
Q
A
Q
E
G
L
R
Site 6
S72
Q
A
Q
E
G
L
R
S
L
Q
H
Q
E
K
Q
Site 7
T91
G
G
W
D
H
G
D
T
Q
S
I
Q
S
S
R
Site 8
S93
W
D
H
G
D
T
Q
S
I
Q
S
S
R
T
G
Site 9
S96
G
D
T
Q
S
I
Q
S
S
R
T
G
P
D
E
Site 10
S97
D
T
Q
S
I
Q
S
S
R
T
G
P
D
E
D
Site 11
S107
G
P
D
E
D
N
I
S
F
C
S
Q
T
T
S
Site 12
S110
E
D
N
I
S
F
C
S
Q
T
T
S
Y
V
A
Site 13
S114
S
F
C
S
Q
T
T
S
Y
V
A
E
S
S
T
Site 14
Y115
F
C
S
Q
T
T
S
Y
V
A
E
S
S
T
A
Site 15
S119
E
D
N
I
S
F
C
S
Q
T
T
S
Y
V
A
Site 16
S127
S
T
A
E
D
A
L
S
I
R
S
E
M
I
Q
Site 17
S138
E
M
I
Q
R
K
G
S
T
F
R
P
H
D
S
Site 18
T139
M
I
Q
R
K
G
S
T
F
R
P
H
D
S
F
Site 19
S145
S
T
F
R
P
H
D
S
F
P
K
S
G
K
S
Site 20
S149
P
H
D
S
F
P
K
S
G
K
S
G
R
R
R
Site 21
S152
S
F
P
K
S
G
K
S
G
R
R
R
R
E
R
Site 22
S161
R
R
R
R
E
R
R
S
T
V
L
G
L
P
Q
Site 23
T162
R
R
R
E
R
R
S
T
V
L
G
L
P
Q
H
Site 24
T185
N
E
R
E
A
P
G
T
P
R
A
P
G
A
R
Site 25
T199
R
D
A
V
R
I
P
T
V
D
G
R
P
R
G
Site 26
T207
V
D
G
R
P
R
G
T
S
G
M
G
A
R
V
Site 27
S208
D
G
R
P
R
G
T
S
G
M
G
A
R
V
S
Site 28
S215
S
G
M
G
A
R
V
S
L
Q
A
L
E
A
E
Site 29
Y241
Q
R
H
I
D
R
V
Y
R
D
D
T
F
V
G
Site 30
T245
D
R
V
Y
R
D
D
T
F
V
G
R
S
T
G
Site 31
T251
D
T
F
V
G
R
S
T
G
T
R
A
P
P
L
Site 32
T259
G
T
R
A
P
P
L
T
R
P
M
S
L
A
V
Site 33
S263
P
P
L
T
R
P
M
S
L
A
V
P
G
L
T
Site 34
S280
A
G
P
A
E
P
L
S
P
A
M
S
I
S
P
Site 35
S284
E
P
L
S
P
A
M
S
I
S
P
Q
A
T
Y
Site 36
S286
L
S
P
A
M
S
I
S
P
Q
A
T
Y
L
S
Site 37
Y291
S
I
S
P
Q
A
T
Y
L
S
K
L
I
P
H
Site 38
T317
L
G
R
C
S
L
R
T
L
S
R
C
S
L
H
Site 39
S319
R
C
S
L
R
T
L
S
R
C
S
L
H
S
A
Site 40
S322
L
R
T
L
S
R
C
S
L
H
S
A
S
P
A
Site 41
S325
L
S
R
C
S
L
H
S
A
S
P
A
S
V
R
Site 42
S327
R
C
S
L
H
S
A
S
P
A
S
V
R
S
L
Site 43
S330
L
H
S
A
S
P
A
S
V
R
S
L
G
R
F
Site 44
S333
A
S
P
A
S
V
R
S
L
G
R
F
S
S
V
Site 45
S338
V
R
S
L
G
R
F
S
S
V
S
S
P
Q
P
Site 46
S339
R
S
L
G
R
F
S
S
V
S
S
P
Q
P
R
Site 47
S341
L
G
R
F
S
S
V
S
S
P
Q
P
R
S
R
Site 48
S342
G
R
F
S
S
V
S
S
P
Q
P
R
S
R
H
Site 49
S347
V
S
S
P
Q
P
R
S
R
H
P
S
S
S
S
Site 50
S351
Q
P
R
S
R
H
P
S
S
S
S
D
T
W
S
Site 51
S352
P
R
S
R
H
P
S
S
S
S
D
T
W
S
H
Site 52
S353
R
S
R
H
P
S
S
S
S
D
T
W
S
H
S
Site 53
S354
S
R
H
P
S
S
S
S
D
T
W
S
H
S
Q
Site 54
T356
H
P
S
S
S
S
D
T
W
S
H
S
Q
S
S
Site 55
S358
S
S
S
S
D
T
W
S
H
S
Q
S
S
D
T
Site 56
S360
S
S
D
T
W
S
H
S
Q
S
S
D
T
I
V
Site 57
S362
D
T
W
S
H
S
Q
S
S
D
T
I
V
S
D
Site 58
S363
T
W
S
H
S
Q
S
S
D
T
I
V
S
D
G
Site 59
T365
S
H
S
Q
S
S
D
T
I
V
S
D
G
S
T
Site 60
S368
Q
S
S
D
T
I
V
S
D
G
S
T
L
S
S
Site 61
S371
D
T
I
V
S
D
G
S
T
L
S
S
K
G
G
Site 62
T372
T
I
V
S
D
G
S
T
L
S
S
K
G
G
S
Site 63
S374
V
S
D
G
S
T
L
S
S
K
G
G
S
E
G
Site 64
S375
S
D
G
S
T
L
S
S
K
G
G
S
E
G
Q
Site 65
S379
T
L
S
S
K
G
G
S
E
G
Q
P
E
S
S
Site 66
S385
G
S
E
G
Q
P
E
S
S
T
A
S
N
S
V
Site 67
S386
S
E
G
Q
P
E
S
S
T
A
S
N
S
V
V
Site 68
T387
E
G
Q
P
E
S
S
T
A
S
N
S
V
V
P
Site 69
S389
Q
P
E
S
S
T
A
S
N
S
V
V
P
P
P
Site 70
S391
E
S
S
T
A
S
N
S
V
V
P
P
P
Q
G
Site 71
S400
V
P
P
P
Q
G
G
S
G
R
G
S
P
S
G
Site 72
S404
Q
G
G
S
G
R
G
S
P
S
G
G
S
T
A
Site 73
S406
G
S
G
R
G
S
P
S
G
G
S
T
A
E
A
Site 74
S409
R
G
S
P
S
G
G
S
T
A
E
A
S
D
T
Site 75
T410
G
S
P
S
G
G
S
T
A
E
A
S
D
T
L
Site 76
S414
G
G
S
T
A
E
A
S
D
T
L
S
I
R
S
Site 77
T416
S
T
A
E
A
S
D
T
L
S
I
R
S
S
G
Site 78
S418
A
E
A
S
D
T
L
S
I
R
S
S
G
Q
L
Site 79
S421
S
D
T
L
S
I
R
S
S
G
Q
L
S
G
R
Site 80
S422
D
T
L
S
I
R
S
S
G
Q
L
S
G
R
S
Site 81
S426
I
R
S
S
G
Q
L
S
G
R
S
V
S
L
R
Site 82
S429
S
G
Q
L
S
G
R
S
V
S
L
R
K
L
K
Site 83
S431
Q
L
S
G
R
S
V
S
L
R
K
L
K
R
P
Site 84
T445
P
P
P
P
P
R
R
T
H
S
L
H
Q
R
G
Site 85
S447
P
P
P
R
R
T
H
S
L
H
Q
R
G
L
A
Site 86
T479
P
Q
L
P
R
P
P
T
T
G
G
S
E
G
A
Site 87
S498
C
P
P
N
P
A
N
S
W
V
P
G
L
S
P
Site 88
S504
N
S
W
V
P
G
L
S
P
G
G
S
R
R
P
Site 89
S508
P
G
L
S
P
G
G
S
R
R
P
P
R
S
P
Site 90
S514
G
S
R
R
P
P
R
S
P
E
R
T
L
S
P
Site 91
T518
P
P
R
S
P
E
R
T
L
S
P
S
S
G
Y
Site 92
S520
R
S
P
E
R
T
L
S
P
S
S
G
Y
S
S
Site 93
S522
P
E
R
T
L
S
P
S
S
G
Y
S
S
Q
S
Site 94
S523
E
R
T
L
S
P
S
S
G
Y
S
S
Q
S
G
Site 95
Y525
T
L
S
P
S
S
G
Y
S
S
Q
S
G
T
P
Site 96
S526
L
S
P
S
S
G
Y
S
S
Q
S
G
T
P
T
Site 97
S527
S
P
S
S
G
Y
S
S
Q
S
G
T
P
T
L
Site 98
S529
R
S
P
E
R
T
L
S
P
S
S
G
Y
S
S
Site 99
T531
G
Y
S
S
Q
S
G
T
P
T
L
P
P
K
G
Site 100
T533
S
S
Q
S
G
T
P
T
L
P
P
K
G
L
A
Site 101
S545
G
L
A
G
P
P
A
S
P
G
K
A
Q
P
P
Site 102
T558
P
P
K
P
E
R
V
T
S
L
R
S
P
G
A
Site 103
S559
P
K
P
E
R
V
T
S
L
R
S
P
G
A
S
Site 104
S562
E
R
V
T
S
L
R
S
P
G
A
S
V
S
S
Site 105
S566
S
L
R
S
P
G
A
S
V
S
S
S
L
T
S
Site 106
S568
R
S
P
G
A
S
V
S
S
S
L
T
S
L
C
Site 107
S573
S
V
S
S
S
L
T
S
L
C
S
S
S
S
D
Site 108
S576
S
S
L
T
S
L
C
S
S
S
S
D
P
A
P
Site 109
S577
S
L
T
S
L
C
S
S
S
S
D
P
A
P
S
Site 110
S578
L
T
S
L
C
S
S
S
S
D
P
A
P
S
D
Site 111
S579
T
S
L
C
S
S
S
S
D
P
A
P
S
D
R
Site 112
S584
S
S
S
D
P
A
P
S
D
R
S
G
P
Q
I
Site 113
S587
D
P
A
P
S
D
R
S
G
P
Q
I
L
T
P
Site 114
T593
R
S
G
P
Q
I
L
T
P
L
G
D
R
F
V
Site 115
S612
P
K
V
P
A
P
F
S
P
P
P
S
K
P
R
Site 116
S616
A
P
F
S
P
P
P
S
K
P
R
S
P
N
P
Site 117
S620
P
P
P
S
K
P
R
S
P
N
P
A
A
P
A
Site 118
S639
A
V
V
P
G
P
V
S
T
T
D
A
S
P
Q
Site 119
T640
V
V
P
G
P
V
S
T
T
D
A
S
P
Q
S
Site 120
S644
P
V
S
T
T
D
A
S
P
Q
S
P
P
T
P
Site 121
S647
T
T
D
A
S
P
Q
S
P
P
T
P
Q
T
T
Site 122
T650
A
S
P
Q
S
P
P
T
P
Q
T
T
L
T
P
Site 123
T654
S
P
P
T
P
Q
T
T
L
T
P
L
Q
E
S
Site 124
T656
P
T
P
Q
T
T
L
T
P
L
Q
E
S
P
V
Site 125
S661
T
L
T
P
L
Q
E
S
P
V
I
S
K
D
Q
Site 126
S665
L
Q
E
S
P
V
I
S
K
D
Q
S
P
P
P
Site 127
S669
P
V
I
S
K
D
Q
S
P
P
P
S
P
P
P
Site 128
S673
K
D
Q
S
P
P
P
S
P
P
P
S
Y
H
P
Site 129
S677
P
P
P
S
P
P
P
S
Y
H
P
P
P
P
P
Site 130
Y678
P
P
S
P
P
P
S
Y
H
P
P
P
P
P
T
Site 131
T685
Y
H
P
P
P
P
P
T
K
K
P
E
V
V
V
Site 132
T700
E
A
P
S
A
S
E
T
A
E
E
P
L
Q
D
Site 133
S724
A
P
E
E
Q
D
L
S
M
A
D
F
P
P
P
Site 134
S737
P
P
E
E
A
F
F
S
V
A
S
P
E
P
A
Site 135
S740
E
A
F
F
S
V
A
S
P
E
P
A
G
P
S
Site 136
S747
S
P
E
P
A
G
P
S
G
S
P
E
L
V
S
Site 137
S749
E
P
A
G
P
S
G
S
P
E
L
V
S
S
P
Site 138
S754
S
G
S
P
E
L
V
S
S
P
A
A
S
S
S
Site 139
S755
G
S
P
E
L
V
S
S
P
A
A
S
S
S
S
Site 140
S761
S
S
P
A
A
S
S
S
S
A
T
A
L
Q
I
Site 141
S762
S
P
A
A
S
S
S
S
A
T
A
L
Q
I
Q
Site 142
S773
L
Q
I
Q
P
P
G
S
P
D
P
P
P
A
P
Site 143
S787
P
P
A
P
A
P
A
S
S
A
P
G
H
V
A
Site 144
S788
P
A
P
A
P
A
S
S
A
P
G
H
V
A
K
Site 145
S805
Q
K
E
P
V
G
C
S
K
G
G
G
P
P
R
Site 146
S847
P
T
P
A
L
G
P
S
A
P
Q
K
P
L
R
Site 147
S858
K
P
L
R
R
A
L
S
G
R
A
S
P
V
P
Site 148
S862
R
A
L
S
G
R
A
S
P
V
P
A
P
S
S
Site 149
S868
A
S
P
V
P
A
P
S
S
G
L
H
A
A
V
Site 150
S869
S
P
V
P
A
P
S
S
G
L
H
A
A
V
R
Site 151
S885
K
A
C
S
L
A
A
S
E
G
L
S
S
A
Q
Site 152
S889
L
A
A
S
E
G
L
S
S
A
Q
P
N
G
P
Site 153
S890
A
A
S
E
G
L
S
S
A
Q
P
N
G
P
P
Site 154
S906
A
E
P
R
P
P
Q
S
P
A
S
T
A
S
F
Site 155
S909
R
P
P
Q
S
P
A
S
T
A
S
F
I
F
S
Site 156
T910
P
P
Q
S
P
A
S
T
A
S
F
I
F
S
K
Site 157
S912
Q
S
P
A
S
T
A
S
F
I
F
S
K
G
S
Site 158
S916
S
T
A
S
F
I
F
S
K
G
S
R
K
L
Q
Site 159
S929
L
Q
L
E
R
P
V
S
P
E
T
Q
A
D
L
Site 160
T932
E
R
P
V
S
P
E
T
Q
A
D
L
Q
R
N
Site 161
S948
V
A
E
L
R
S
I
S
E
Q
R
P
P
Q
A
Site 162
S959
P
P
Q
A
P
K
K
S
P
K
A
P
P
P
V
Site 163
S971
P
P
V
A
R
K
P
S
V
G
V
P
P
P
A
Site 164
S979
V
G
V
P
P
P
A
S
P
S
Y
P
R
A
E
Site 165
S981
V
P
P
P
A
S
P
S
Y
P
R
A
E
P
L
Site 166
Y982
P
P
P
A
S
P
S
Y
P
R
A
E
P
L
T
Site 167
T989
Y
P
R
A
E
P
L
T
A
P
P
T
N
G
L
Site 168
T993
E
P
L
T
A
P
P
T
N
G
L
P
H
T
Q
Site 169
T999
P
T
N
G
L
P
H
T
Q
D
R
T
K
R
E
Site 170
S1028
E
K
M
G
L
P
G
S
D
S
Q
K
E
L
A
Site 171
S1030
M
G
L
P
G
S
D
S
Q
K
E
L
A
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation