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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZSWIM5
Full Name:
Zinc finger SWIM domain-containing protein 5
Alias:
KIAA1511; KIAA1511, zinc finger SWIM domain containing protein 5; Zinc finger, SWIM-type containing 5; ZSW5; ZSWM5
Type:
Unknown function
Mass (Da):
130634
Number AA:
1185
UniProt ID:
Q9P217
International Prot ID:
IPI00001653
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
G
E
R
E
E
L
L
S
P
S
P
V
S
P
A
Site 2
S14
R
E
E
L
L
S
P
S
P
V
S
P
A
K
R
Site 3
S17
L
L
S
P
S
P
V
S
P
A
K
R
Q
C
S
Site 4
S24
S
P
A
K
R
Q
C
S
W
P
S
P
Q
A
H
Site 5
S27
K
R
Q
C
S
W
P
S
P
Q
A
H
H
P
R
Site 6
S36
Q
A
H
H
P
R
G
S
P
G
A
A
G
G
G
Site 7
S64
R
P
H
L
Q
P
D
S
L
L
D
C
A
A
K
Site 8
Y79
T
V
A
E
K
W
A
Y
E
R
V
E
E
R
F
Site 9
Y99
P
V
Q
R
R
I
V
Y
W
S
F
P
R
N
E
Site 10
S101
Q
R
R
I
V
Y
W
S
F
P
R
N
E
R
E
Site 11
Y112
N
E
R
E
I
C
M
Y
S
S
F
Q
Y
R
G
Site 12
Y117
C
M
Y
S
S
F
Q
Y
R
G
G
P
G
A
G
Site 13
S133
A
G
G
A
A
G
A
S
P
A
E
E
G
P
Q
Site 14
S213
V
T
E
L
A
T
A
S
E
P
A
V
T
Y
K
Site 15
Y254
H
V
V
A
L
S
L
Y
R
I
R
K
P
D
Q
Site 16
T271
L
R
L
P
I
S
E
T
L
F
Q
M
N
R
D
Site 17
Y286
Q
L
Q
K
F
I
Q
Y
L
I
T
A
H
H
T
Site 18
S309
L
A
D
E
I
L
S
S
N
S
E
I
N
Q
V
Site 19
T323
V
N
G
A
P
D
P
T
A
G
A
S
I
D
D
Site 20
S350
E
Q
V
K
L
F
L
S
Q
G
G
Y
C
G
S
Site 21
Y354
L
F
L
S
Q
G
G
Y
C
G
S
G
K
Q
L
Site 22
S357
S
Q
G
G
Y
C
G
S
G
K
Q
L
N
S
M
Site 23
S377
E
M
L
R
M
R
D
S
N
G
A
R
M
L
T
Site 24
T397
F
V
A
D
P
R
L
T
L
W
R
Q
Q
G
T
Site 25
Y458
C
P
L
E
D
G
N
Y
G
H
E
L
P
N
I
Site 26
S472
I
T
N
A
L
P
Q
S
A
I
H
S
P
D
S
Site 27
S476
L
P
Q
S
A
I
H
S
P
D
S
L
S
R
P
Site 28
S479
S
A
I
H
S
P
D
S
L
S
R
P
R
R
T
Site 29
S481
I
H
S
P
D
S
L
S
R
P
R
R
T
V
F
Site 30
T486
S
L
S
R
P
R
R
T
V
F
T
R
A
I
E
Site 31
T489
R
P
R
R
T
V
F
T
R
A
I
E
G
R
E
Site 32
S509
S
H
L
Q
R
I
I
S
S
D
V
Y
T
A
P
Site 33
Y513
R
I
I
S
S
D
V
Y
T
A
P
A
C
Q
R
Site 34
T514
I
I
S
S
D
V
Y
T
A
P
A
C
Q
R
E
Site 35
S522
A
P
A
C
Q
R
E
S
E
R
L
L
F
N
S
Site 36
S529
S
E
R
L
L
F
N
S
Q
G
Q
P
L
W
L
Site 37
Y554
D
A
L
R
S
H
G
Y
P
K
E
A
L
R
L
Site 38
Y580
Q
Q
R
Q
L
E
I
Y
K
H
Q
K
K
E
L
Site 39
T592
K
E
L
L
Q
R
G
T
T
T
I
T
N
L
E
Site 40
T593
E
L
L
Q
R
G
T
T
T
I
T
N
L
E
G
Site 41
Y627
C
R
L
N
D
D
G
Y
L
E
M
S
D
M
N
Site 42
S631
D
D
G
Y
L
E
M
S
D
M
N
E
S
R
P
Site 43
S636
E
M
S
D
M
N
E
S
R
P
P
V
Y
Q
H
Site 44
Y641
N
E
S
R
P
P
V
Y
Q
H
V
P
V
A
A
Site 45
S650
H
V
P
V
A
A
G
S
P
N
S
S
E
S
Y
Site 46
S653
V
A
A
G
S
P
N
S
S
E
S
Y
L
S
L
Site 47
S654
A
A
G
S
P
N
S
S
E
S
Y
L
S
L
A
Site 48
S656
G
S
P
N
S
S
E
S
Y
L
S
L
A
L
E
Site 49
Y657
S
P
N
S
S
E
S
Y
L
S
L
A
L
E
V
Site 50
Y680
R
L
M
P
E
G
L
Y
A
Q
D
K
V
C
R
Site 51
S694
R
N
E
E
Q
L
L
S
Q
L
Q
E
L
Q
L
Site 52
S733
G
E
V
I
H
R
E
S
V
P
M
H
T
F
A
Site 53
T738
R
E
S
V
P
M
H
T
F
A
K
Y
L
F
S
Site 54
S755
L
P
H
D
P
D
L
S
Y
K
L
A
L
R
A
Site 55
Y756
P
H
D
P
D
L
S
Y
K
L
A
L
R
A
M
Site 56
S771
R
L
P
V
L
E
N
S
A
S
A
G
D
T
S
Site 57
S773
P
V
L
E
N
S
A
S
A
G
D
T
S
H
P
Site 58
T777
N
S
A
S
A
G
D
T
S
H
P
H
H
M
V
Site 59
S778
S
A
S
A
G
D
T
S
H
P
H
H
M
V
S
Site 60
S785
S
H
P
H
H
M
V
S
V
V
P
S
R
Y
P
Site 61
Y791
V
S
V
V
P
S
R
Y
P
R
W
F
T
L
G
Site 62
T796
S
R
Y
P
R
W
F
T
L
G
H
L
E
S
Q
Site 63
S802
F
T
L
G
H
L
E
S
Q
Q
C
E
L
A
S
Site 64
T824
G
D
T
L
R
L
R
T
I
L
E
A
I
Q
K
Site 65
S835
A
I
Q
K
H
I
H
S
S
S
L
I
F
K
L
Site 66
S837
Q
K
H
I
H
S
S
S
L
I
F
K
L
A
Q
Site 67
T851
Q
D
A
F
K
I
A
T
P
T
D
S
S
T
D
Site 68
T853
A
F
K
I
A
T
P
T
D
S
S
T
D
S
T
Site 69
S855
K
I
A
T
P
T
D
S
S
T
D
S
T
L
L
Site 70
S856
I
A
T
P
T
D
S
S
T
D
S
T
L
L
N
Site 71
T857
A
T
P
T
D
S
S
T
D
S
T
L
L
N
V
Site 72
S859
P
T
D
S
S
T
D
S
T
L
L
N
V
A
L
Site 73
T860
T
D
S
S
T
D
S
T
L
L
N
V
A
L
E
Site 74
T876
G
L
Q
V
M
R
M
T
L
S
T
L
N
W
R
Site 75
T879
V
M
R
M
T
L
S
T
L
N
W
R
R
R
E
Site 76
T915
Q
S
W
Y
T
L
F
T
P
T
E
A
T
S
I
Site 77
S937
H
T
T
I
L
R
L
S
L
D
Y
P
Q
R
E
Site 78
Y940
I
L
R
L
S
L
D
Y
P
Q
R
E
E
L
A
Site 79
S948
P
Q
R
E
E
L
A
S
C
A
R
T
L
A
L
Site 80
S968
D
P
Q
S
C
A
L
S
A
L
T
L
C
E
K
Site 81
Y984
H
I
A
F
E
A
A
Y
Q
I
A
I
D
A
A
Site 82
Y1006
Q
L
F
T
I
A
R
Y
M
E
L
R
G
Y
P
Site 83
Y1012
R
Y
M
E
L
R
G
Y
P
L
R
A
F
K
L
Site 84
S1096
A
G
I
P
G
R
R
S
S
G
K
L
M
S
T
Site 85
S1097
G
I
P
G
R
R
S
S
G
K
L
M
S
T
D
Site 86
S1102
R
S
S
G
K
L
M
S
T
D
K
A
P
L
R
Site 87
T1103
S
S
G
K
L
M
S
T
D
K
A
P
L
R
Q
Site 88
T1128
N
T
T
H
S
R
L
T
H
I
S
P
R
H
Y
Site 89
S1131
H
S
R
L
T
H
I
S
P
R
H
Y
G
E
F
Site 90
Y1135
T
H
I
S
P
R
H
Y
G
E
F
I
E
F
L
Site 91
T1148
F
L
S
K
A
R
E
T
F
L
L
P
Q
D
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation