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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DNAH2
Full Name:
Dynein heavy chain 2, axonemal
Alias:
Axonemal beta dynein heavy chain 2; DNAHC2; DNHD3; Dynein, axonemal, heavy chain 2; FLJ46675; KIAA1503
Type:
Unknown function
Mass (Da):
507698
Number AA:
4427
UniProt ID:
Q9P225
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005858
GO:0035085
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
GO:0003777
PhosphoSite+
KinaseNET
Biological Process:
GO:0001539
GO:0007018
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
A
E
K
K
Q
R
L
S
G
R
G
S
S
Q
A
Site 2
S16
Q
R
L
S
G
R
G
S
S
Q
A
S
W
S
G
Site 3
S17
R
L
S
G
R
G
S
S
Q
A
S
W
S
G
R
Site 4
S20
G
R
G
S
S
Q
A
S
W
S
G
R
A
T
R
Site 5
S22
G
S
S
Q
A
S
W
S
G
R
A
T
R
A
A
Site 6
T26
A
S
W
S
G
R
A
T
R
A
A
V
A
T
Q
Site 7
T32
A
T
R
A
A
V
A
T
Q
E
Q
G
N
A
P
Site 8
S69
P
Q
A
Q
S
E
E
S
V
E
P
E
A
D
V
Site 9
T110
E
H
F
A
Q
D
P
T
E
S
I
L
T
I
F
Site 10
Y140
Q
T
Q
N
Q
L
V
Y
F
I
R
Q
A
P
V
Site 11
T150
R
Q
A
P
V
P
I
T
W
E
N
F
E
A
T
Site 12
T162
E
A
T
V
Q
F
G
T
V
R
G
P
Y
I
P
Site 13
T187
A
P
Q
I
F
A
N
T
G
W
P
E
S
I
R
Site 14
S199
S
I
R
N
H
F
A
S
H
L
H
K
F
L
A
Site 15
Y213
A
C
L
T
D
T
R
Y
K
L
E
G
H
T
V
Site 16
T247
E
L
V
Q
R
L
E
T
S
M
I
H
W
T
R
Site 17
T265
E
M
L
S
A
Q
E
T
V
E
T
G
E
N
L
Site 18
T268
S
A
Q
E
T
V
E
T
G
E
N
L
G
P
L
Site 19
S289
R
N
R
C
M
D
L
S
G
I
S
K
Q
L
V
Site 20
S334
D
G
S
R
Q
A
Q
S
N
L
T
F
L
S
I
Site 21
T337
R
Q
A
Q
S
N
L
T
F
L
S
I
L
K
E
Site 22
S340
Q
S
N
L
T
F
L
S
I
L
K
E
P
Y
Q
Site 23
Y346
L
S
I
L
K
E
P
Y
Q
E
L
A
F
M
K
Site 24
S359
M
K
P
K
D
I
S
S
K
L
P
K
L
I
S
Site 25
Y378
I
W
V
N
S
P
H
Y
N
T
R
E
R
L
T
Site 26
T385
Y
N
T
R
E
R
L
T
S
L
F
R
K
V
C
Site 27
S386
N
T
R
E
R
L
T
S
L
F
R
K
V
C
D
Site 28
T437
I
F
H
K
N
L
H
T
L
R
A
V
R
G
G
Site 29
S500
D
T
F
H
R
L
A
S
R
E
A
I
K
R
T
Site 30
Y508
R
E
A
I
K
R
T
Y
D
K
K
A
V
D
L
Site 31
Y516
D
K
K
A
V
D
L
Y
M
L
F
N
S
E
L
Site 32
Y540
K
W
P
D
L
E
P
Y
V
A
Q
Y
S
G
K
Site 33
T563
R
R
I
D
R
V
M
T
C
L
A
G
A
H
F
Site 34
T576
H
F
L
P
R
I
G
T
G
K
E
S
V
H
T
Site 35
T583
T
G
K
E
S
V
H
T
Y
Q
Q
M
V
Q
A
Site 36
Y584
G
K
E
S
V
H
T
Y
Q
Q
M
V
Q
A
I
Site 37
T598
I
D
E
L
V
R
K
T
F
Q
E
W
T
S
S
Site 38
S605
T
F
Q
E
W
T
S
S
L
D
K
D
C
I
R
Site 39
T616
D
C
I
R
R
L
D
T
P
L
L
R
I
S
Q
Site 40
S622
D
T
P
L
L
R
I
S
Q
E
K
A
G
M
L
Site 41
T654
W
E
R
L
L
F
E
T
P
H
Y
V
V
N
V
Site 42
S759
G
W
R
A
Q
E
M
S
E
K
L
L
V
R
I
Site 43
S767
E
K
L
L
V
R
I
S
G
K
R
V
Y
R
D
Site 44
Y772
R
I
S
G
K
R
V
Y
R
D
L
E
F
E
E
Site 45
T801
N
L
H
Q
D
V
V
T
I
M
T
N
S
Y
E
Site 46
S848
K
W
S
L
L
E
L
S
K
A
I
N
G
D
G
Site 47
T857
A
I
N
G
D
G
K
T
S
P
N
P
L
F
Q
Site 48
S858
I
N
G
D
G
K
T
S
P
N
P
L
F
Q
V
Site 49
S876
L
K
N
D
L
Q
G
S
V
A
Q
V
E
F
S
Site 50
T915
C
H
L
P
D
I
L
T
K
R
K
L
H
R
E
Site 51
T926
L
H
R
E
P
I
Q
T
V
V
E
Q
D
E
D
Site 52
T939
E
D
I
K
K
I
Q
T
Q
I
S
S
G
M
T
Site 53
T946
T
Q
I
S
S
G
M
T
N
N
A
S
L
L
Q
Site 54
S950
S
G
M
T
N
N
A
S
L
L
Q
N
Y
L
K
Site 55
Y977
K
D
S
F
I
H
R
Y
Q
R
L
N
P
P
V
Site 56
T995
V
A
D
I
A
R
Y
T
E
V
A
N
N
V
Q
Site 57
Y1053
R
L
L
E
L
H
T
Y
L
K
E
N
A
E
K
Site 58
T1067
K
I
S
R
P
P
Q
T
L
E
E
L
G
V
S
Site 59
T1090
H
D
L
A
N
V
E
T
Q
I
P
P
I
H
E
Site 60
Y1105
Q
F
A
I
L
E
K
Y
E
V
P
V
E
D
S
Site 61
S1112
Y
E
V
P
V
E
D
S
V
L
E
M
L
D
S
Site 62
T1130
E
W
V
V
F
Q
Q
T
L
L
D
S
K
Q
M
Site 63
T1147
K
H
K
E
K
F
K
T
G
L
I
H
S
A
D
Site 64
S1152
F
K
T
G
L
I
H
S
A
D
D
F
K
K
K
Site 65
Y1179
H
F
T
S
N
V
G
Y
M
S
A
L
D
Q
I
Site 66
S1202
A
M
R
E
E
E
N
S
L
R
A
N
L
G
I
Site 67
S1217
F
K
I
E
Q
P
P
S
K
D
L
Q
N
L
E
Site 68
T1262
L
Q
T
E
T
M
E
T
T
A
H
G
L
F
R
Site 69
T1272
H
G
L
F
R
R
L
T
K
L
A
K
E
Y
K
Site 70
T1288
R
N
W
E
I
I
E
T
T
R
S
K
I
E
Q
Site 71
S1291
E
I
I
E
T
T
R
S
K
I
E
Q
F
K
R
Site 72
S1304
K
R
T
M
P
L
I
S
D
L
R
N
P
A
L
Site 73
S1331
Q
R
E
F
D
Q
E
S
E
S
F
T
L
E
Q
Site 74
S1333
E
F
D
Q
E
S
E
S
F
T
L
E
Q
I
V
Site 75
T1335
D
Q
E
S
E
S
F
T
L
E
Q
I
V
E
L
Site 76
T1374
A
L
Q
N
I
A
K
T
W
D
V
T
Q
L
D
Site 77
Y1385
T
Q
L
D
I
V
P
Y
K
D
K
G
H
H
R
Site 78
T1396
G
H
H
R
L
R
G
T
E
E
V
F
Q
A
L
Site 79
S1411
E
D
N
Q
V
A
L
S
T
M
K
A
S
R
F
Site 80
Y1452
T
V
Q
R
Q
W
M
Y
L
E
N
I
F
L
G
Site 81
T1471
K
Q
L
P
N
E
S
T
L
F
D
Q
V
N
S
Site 82
T1497
D
N
N
A
L
R
S
T
H
H
P
G
L
L
D
Site 83
S1519
I
L
E
D
I
Q
K
S
L
D
M
Y
L
E
T
Site 84
Y1523
I
Q
K
S
L
D
M
Y
L
E
T
K
R
H
I
Site 85
T1526
S
L
D
M
Y
L
E
T
K
R
H
I
F
P
R
Site 86
Y1535
R
H
I
F
P
R
F
Y
F
L
S
N
D
D
L
Site 87
S1579
Q
K
V
G
G
P
S
S
K
W
E
A
V
G
M
Site 88
T1616
W
L
G
D
V
E
Q
T
M
R
V
T
L
R
D
Site 89
T1620
V
E
Q
T
M
R
V
T
L
R
D
L
L
R
N
Site 90
Y1727
R
D
V
L
E
K
L
Y
K
S
G
L
M
D
V
Site 91
S1729
V
L
E
K
L
Y
K
S
G
L
M
D
V
N
S
Site 92
S1736
S
G
L
M
D
V
N
S
F
D
W
L
S
Q
L
Site 93
Y1746
W
L
S
Q
L
R
F
Y
W
E
K
D
L
D
D
Site 94
Y1765
Q
T
N
T
Q
F
Q
Y
N
Y
E
Y
L
G
N
Site 95
Y1767
N
T
Q
F
Q
Y
N
Y
E
Y
L
G
N
S
G
Site 96
Y1769
Q
F
Q
Y
N
Y
E
Y
L
G
N
S
G
R
L
Site 97
T1779
N
S
G
R
L
V
I
T
P
L
T
D
R
C
Y
Site 98
S1800
L
H
L
H
R
G
G
S
P
K
G
P
A
G
T
Site 99
T1812
A
G
T
G
K
T
E
T
V
K
D
L
G
K
A
Site 100
Y1835
N
C
S
E
G
L
D
Y
K
S
M
G
R
M
Y
Site 101
S1837
S
E
G
L
D
Y
K
S
M
G
R
M
Y
S
G
Site 102
Y1842
Y
K
S
M
G
R
M
Y
S
G
L
A
Q
T
G
Site 103
S1843
K
S
M
G
R
M
Y
S
G
L
A
Q
T
G
A
Site 104
Y1909
F
I
T
M
N
P
G
Y
A
G
R
T
E
L
P
Site 105
S1921
E
L
P
E
N
L
K
S
M
F
R
P
I
A
M
Site 106
S1961
K
K
V
Y
T
L
Y
S
L
A
V
Q
Q
L
S
Site 107
Y1973
Q
L
S
R
Q
D
H
Y
D
F
G
L
R
A
L
Site 108
Y1986
A
L
T
S
L
L
R
Y
A
G
K
K
R
R
L
Site 109
T1998
R
R
L
Q
P
D
L
T
D
E
E
V
L
L
L
Site 110
T2047
D
Y
G
K
L
R
E
T
V
E
Q
E
I
R
D
Site 111
S2059
I
R
D
M
G
L
Q
S
T
P
F
T
L
T
K
Site 112
T2060
R
D
M
G
L
Q
S
T
P
F
T
L
T
K
V
Site 113
T2065
Q
S
T
P
F
T
L
T
K
V
F
Q
L
Y
E
Site 114
Y2071
L
T
K
V
F
Q
L
Y
E
T
K
N
S
R
H
Site 115
S2079
E
T
K
N
S
R
H
S
T
M
I
V
G
C
T
Site 116
T2080
T
K
N
S
R
H
S
T
M
I
V
G
C
T
G
Site 117
T2086
S
T
M
I
V
G
C
T
G
S
G
K
T
A
S
Site 118
S2088
M
I
V
G
C
T
G
S
G
K
T
A
S
W
R
Site 119
S2093
T
G
S
G
K
T
A
S
W
R
I
L
Q
A
S
Site 120
Y2131
A
L
S
L
G
E
L
Y
G
E
Y
D
L
S
T
Site 121
Y2134
L
G
E
L
Y
G
E
Y
D
L
S
T
N
E
W
Site 122
S2137
L
Y
G
E
Y
D
L
S
T
N
E
W
T
D
G
Site 123
T2138
Y
G
E
Y
D
L
S
T
N
E
W
T
D
G
I
Site 124
Y2229
C
G
M
V
Y
T
D
Y
A
D
L
G
W
K
P
Site 125
Y2237
A
D
L
G
W
K
P
Y
V
Q
S
W
L
E
K
Site 126
S2286
P
E
Y
S
G
I
T
S
L
C
K
L
Y
S
A
Site 127
S2292
T
S
L
C
K
L
Y
S
A
L
A
T
P
E
N
Site 128
T2296
K
L
Y
S
A
L
A
T
P
E
N
G
V
N
P
Site 129
Y2309
N
P
A
D
G
E
N
Y
V
T
M
V
E
M
T
Site 130
S2328
M
I
W
S
V
C
A
S
V
D
E
E
G
R
K
Site 131
S2339
E
G
R
K
R
I
D
S
Y
L
R
E
I
E
G
Site 132
Y2340
G
R
K
R
I
D
S
Y
L
R
E
I
E
G
S
Site 133
S2347
Y
L
R
E
I
E
G
S
F
P
N
K
D
T
V
Site 134
T2353
G
S
F
P
N
K
D
T
V
Y
E
Y
F
V
D
Site 135
Y2355
F
P
N
K
D
T
V
Y
E
Y
F
V
D
P
K
Site 136
Y2357
N
K
D
T
V
Y
E
Y
F
V
D
P
K
I
R
Site 137
T2367
D
P
K
I
R
S
W
T
S
F
E
D
K
L
P
Site 138
S2368
P
K
I
R
S
W
T
S
F
E
D
K
L
P
K
Site 139
S2376
F
E
D
K
L
P
K
S
W
R
Y
P
P
N
A
Site 140
Y2379
K
L
P
K
S
W
R
Y
P
P
N
A
P
F
Y
Site 141
Y2398
P
T
V
D
T
V
R
Y
N
Y
L
V
S
S
L
Site 142
S2428
G
K
T
S
I
A
Q
S
V
L
Q
S
L
P
S
Site 143
S2432
I
A
Q
S
V
L
Q
S
L
P
S
S
Q
W
S
Site 144
S2446
S
V
L
V
V
N
M
S
A
Q
T
T
S
N
N
Site 145
S2456
T
T
S
N
N
V
Q
S
I
I
E
S
R
V
E
Site 146
S2460
N
V
Q
S
I
I
E
S
R
V
E
K
R
T
K
Site 147
T2466
E
S
R
V
E
K
R
T
K
G
V
Y
V
P
F
Site 148
Y2470
E
K
R
T
K
G
V
Y
V
P
F
G
G
K
S
Site 149
S2495
P
A
K
D
M
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G
S
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P
P
L
E
L
I
Site 150
Y2508
L
I
R
L
W
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D
Y
G
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W
Y
D
R
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Site 151
Y2521
R
T
K
Q
T
I
K
Y
I
R
E
M
F
L
M
Site 152
T2539
G
P
P
G
G
G
R
T
V
I
S
P
R
L
R
Site 153
S2542
G
G
G
R
T
V
I
S
P
R
L
R
S
R
F
Site 154
T2555
R
F
N
I
I
N
M
T
F
P
T
K
S
Q
I
Site 155
Y2596
T
E
A
T
L
D
M
Y
N
T
V
V
Q
R
F
Site 156
T2606
V
V
Q
R
F
L
P
T
P
T
K
M
H
Y
L
Site 157
Y2612
P
T
P
T
K
M
H
Y
L
F
N
L
R
D
I
Site 158
T2636
A
N
K
D
F
H
D
T
K
S
S
I
T
R
L
Site 159
S2653
H
E
C
F
R
V
F
S
D
R
L
V
D
A
A
Site 160
Y2703
F
L
K
E
P
K
V
Y
E
D
L
T
D
L
T
Site 161
T2707
P
K
V
Y
E
D
L
T
D
L
T
V
L
K
T
Site 162
T2710
Y
E
D
L
T
D
L
T
V
L
K
T
V
M
E
Site 163
S2726
A
L
N
E
Y
N
L
S
P
S
V
V
P
M
Q
Site 164
S2728
N
E
Y
N
L
S
P
S
V
V
P
M
Q
L
V
Site 165
S2770
I
G
G
S
G
R
Q
S
L
A
R
L
A
S
S
Site 166
S2776
Q
S
L
A
R
L
A
S
S
I
C
D
Y
T
T
Site 167
T2783
S
S
I
C
D
Y
T
T
F
Q
I
E
V
T
K
Site 168
Y2805
R
D
D
I
K
R
L
Y
R
Q
A
G
V
E
L
Site 169
S2828
D
T
Q
I
A
D
E
S
F
L
E
D
I
N
N
Site 170
S2838
E
D
I
N
N
I
L
S
S
G
E
V
P
N
L
Site 171
S2839
D
I
N
N
I
L
S
S
G
E
V
P
N
L
Y
Site 172
Y2846
S
G
E
V
P
N
L
Y
K
P
D
E
F
E
E
Site 173
S2870
R
V
E
Q
V
P
E
S
S
D
S
L
F
A
Y
Site 174
S2871
V
E
Q
V
P
E
S
S
D
S
L
F
A
Y
L
Site 175
S2873
Q
V
P
E
S
S
D
S
L
F
A
Y
L
I
E
Site 176
Y2877
S
S
D
S
L
F
A
Y
L
I
E
R
V
Q
N
Site 177
T2941
L
I
G
V
D
L
G
T
Q
E
N
I
H
R
K
Site 178
Y2976
L
E
L
R
R
H
N
Y
V
T
P
T
K
Y
L
Site 179
T2978
L
R
R
H
N
Y
V
T
P
T
K
Y
L
E
L
Site 180
Y2982
N
Y
V
T
P
T
K
Y
L
E
L
L
S
G
Y
Site 181
S2987
T
K
Y
L
E
L
L
S
G
Y
K
K
L
L
G
Site 182
Y3045
F
Q
K
Q
C
E
E
Y
L
V
I
I
V
Q
Q
Site 183
S3104
E
A
M
R
A
L
E
S
L
N
K
K
D
I
G
Site 184
S3115
K
D
I
G
E
I
K
S
Y
G
R
P
P
A
Q
Site 185
Y3116
D
I
G
E
I
K
S
Y
G
R
P
P
A
Q
V
Site 186
S3155
G
E
Q
N
F
I
K
S
L
I
N
F
D
K
D
Site 187
S3165
N
F
D
K
D
N
I
S
D
K
V
L
K
K
I
Site 188
Y3206
W
V
R
A
M
E
L
Y
G
R
L
Y
R
V
V
Site 189
Y3210
M
E
L
Y
G
R
L
Y
R
V
V
E
P
K
R
Site 190
S3269
K
E
E
L
R
K
K
S
E
E
M
E
L
K
L
Site 191
S3284
E
R
A
G
M
L
V
S
G
L
A
G
E
K
A
Site 192
T3296
E
K
A
R
W
E
E
T
V
Q
G
L
E
E
D
Site 193
Y3328
M
G
P
F
L
T
N
Y
R
D
E
I
V
N
Q
Site 194
S3349
W
E
L
Q
V
P
C
S
P
S
F
A
I
D
N
Site 195
S3374
W
N
I
Q
G
L
P
S
D
A
F
S
T
E
N
Site 196
Y3424
I
D
L
Q
M
S
D
Y
L
R
I
L
E
H
A
Site 197
Y3446
L
L
Q
N
V
Q
E
Y
L
D
P
T
L
N
P
Site 198
T3450
V
Q
E
Y
L
D
P
T
L
N
P
M
L
N
K
Site 199
S3458
L
N
P
M
L
N
K
S
V
A
R
I
G
G
R
Site 200
Y3477
I
G
D
K
E
V
E
Y
N
T
N
F
R
F
Y
Site 201
Y3484
Y
N
T
N
F
R
F
Y
I
T
T
K
L
S
N
Site 202
Y3494
T
K
L
S
N
P
H
Y
S
P
E
T
S
A
K
Site 203
S3495
K
L
S
N
P
H
Y
S
P
E
T
S
A
K
T
Site 204
S3499
P
H
Y
S
P
E
T
S
A
K
T
T
I
V
N
Site 205
T3503
P
E
T
S
A
K
T
T
I
V
N
F
A
V
K
Site 206
S3536
E
L
E
E
Q
K
D
S
L
V
I
N
I
A
A
Site 207
T3575
D
D
V
Q
L
V
N
T
L
H
T
S
K
I
T
Site 208
T3592
E
V
T
E
Q
L
E
T
S
E
T
T
E
I
N
Site 209
T3595
E
Q
L
E
T
S
E
T
T
E
I
N
T
D
L
Site 210
Y3607
T
D
L
A
R
E
A
Y
R
P
C
A
Q
R
A
Site 211
Y3631
M
G
C
I
D
P
M
Y
Q
F
S
L
D
A
Y
Site 212
Y3638
Y
Q
F
S
L
D
A
Y
I
S
L
F
I
L
S
Site 213
S3649
F
I
L
S
I
D
K
S
H
R
S
N
K
L
E
Site 214
Y3661
K
L
E
D
R
I
D
Y
L
N
D
Y
H
T
Y
Site 215
Y3665
R
I
D
Y
L
N
D
Y
H
T
Y
A
V
Y
R
Site 216
Y3671
D
Y
H
T
Y
A
V
Y
R
Y
T
C
R
T
L
Site 217
Y3673
H
T
Y
A
V
Y
R
Y
T
C
R
T
L
F
E
Site 218
T3677
V
Y
R
Y
T
C
R
T
L
F
E
R
H
K
L
Site 219
Y3706
G
K
L
N
M
D
E
Y
N
F
F
L
R
G
G
Site 220
Y3734
S
S
W
L
A
D
A
Y
W
D
N
I
T
E
L
Site 221
T3745
I
T
E
L
D
K
L
T
N
F
H
G
L
M
N
Site 222
Y3765
P
R
D
W
H
L
W
Y
T
N
A
A
P
E
K
Site 223
S3794
Q
R
M
L
I
V
R
S
L
R
Q
D
R
V
A
Site 224
S3826
P
P
V
L
N
M
K
S
V
L
E
D
S
T
P
Site 225
S3831
M
K
S
V
L
E
D
S
T
P
R
S
P
L
V
Site 226
T3832
K
S
V
L
E
D
S
T
P
R
S
P
L
V
F
Site 227
S3868
A
Q
R
F
H
A
L
S
L
G
Q
G
Q
A
P
Site 228
S3921
Q
V
E
D
P
H
P
S
F
R
L
W
L
S
S
Site 229
S3927
P
S
F
R
L
W
L
S
S
I
P
H
P
D
F
Site 230
S3928
S
F
R
L
W
L
S
S
I
P
H
P
D
F
P
Site 231
T3946
L
Q
V
S
I
K
M
T
T
E
P
P
K
G
L
Site 232
T3947
Q
V
S
I
K
M
T
T
E
P
P
K
G
L
K
Site 233
T3958
K
G
L
K
A
N
M
T
R
L
Y
Q
L
M
S
Site 234
Y3961
K
A
N
M
T
R
L
Y
Q
L
M
S
E
P
Q
Site 235
S3965
T
R
L
Y
Q
L
M
S
E
P
Q
F
S
R
C
Site 236
S3970
L
M
S
E
P
Q
F
S
R
C
S
K
P
A
K
Site 237
S3973
E
P
Q
F
S
R
C
S
K
P
A
K
Y
K
K
Site 238
Y3978
R
C
S
K
P
A
K
Y
K
K
L
L
F
S
L
Site 239
Y4007
Q
L
G
W
N
I
I
Y
G
F
N
D
S
D
F
Site 240
S4012
I
I
Y
G
F
N
D
S
D
F
E
V
S
E
N
Site 241
S4017
N
D
S
D
F
E
V
S
E
N
L
L
S
L
Y
Site 242
S4022
E
V
S
E
N
L
L
S
L
Y
L
D
E
Y
E
Site 243
Y4024
S
E
N
L
L
S
L
Y
L
D
E
Y
E
E
T
Site 244
Y4028
L
S
L
Y
L
D
E
Y
E
E
T
P
W
D
A
Site 245
T4031
Y
L
D
E
Y
E
E
T
P
W
D
A
L
K
Y
Site 246
Y4061
D
R
R
L
L
T
T
Y
I
N
D
Y
F
C
D
Site 247
Y4065
L
T
T
Y
I
N
D
Y
F
C
D
Q
S
L
S
Site 248
S4072
Y
F
C
D
Q
S
L
S
T
P
F
H
R
L
S
Site 249
T4073
F
C
D
Q
S
L
S
T
P
F
H
R
L
S
A
Site 250
S4079
S
T
P
F
H
R
L
S
A
L
E
T
Y
F
I
Site 251
T4083
H
R
L
S
A
L
E
T
Y
F
I
P
K
D
G
Site 252
Y4084
R
L
S
A
L
E
T
Y
F
I
P
K
D
G
S
Site 253
S4091
Y
F
I
P
K
D
G
S
L
A
S
Y
K
E
Y
Site 254
S4094
P
K
D
G
S
L
A
S
Y
K
E
Y
I
S
L
Site 255
Y4095
K
D
G
S
L
A
S
Y
K
E
Y
I
S
L
L
Site 256
S4100
A
S
Y
K
E
Y
I
S
L
L
P
G
M
D
P
Site 257
T4132
E
A
Q
T
L
F
D
T
L
L
S
L
Q
P
Q
Site 258
T4141
L
S
L
Q
P
Q
I
T
P
T
R
A
G
G
Q
Site 259
Y4171
K
I
P
E
M
I
D
Y
E
G
T
Q
K
L
L
Site 260
Y4196
L
L
Q
E
I
Q
R
Y
N
T
L
M
Q
T
I
Site 261
T4198
Q
E
I
Q
R
Y
N
T
L
M
Q
T
I
L
F
Site 262
Y4244
P
P
L
W
G
K
A
Y
P
S
Q
K
P
L
A
Site 263
S4246
L
W
G
K
A
Y
P
S
Q
K
P
L
A
A
W
Site 264
S4269
E
Q
F
E
L
W
A
S
R
A
R
P
P
V
I
Site 265
S4296
L
T
A
V
L
Q
S
S
A
R
Q
N
N
V
S
Site 266
S4303
S
A
R
Q
N
N
V
S
V
D
S
L
S
W
E
Site 267
S4306
Q
N
N
V
S
V
D
S
L
S
W
E
F
I
V
Site 268
S4319
I
V
S
T
V
D
D
S
N
L
V
Y
P
P
K
Site 269
Y4323
V
D
D
S
N
L
V
Y
P
P
K
D
G
V
W
Site 270
S4346
A
G
W
D
R
K
N
S
C
L
V
E
A
E
P
Site 271
S4370
I
H
F
R
P
A
E
S
R
K
K
S
A
K
G
Site 272
S4374
P
A
E
S
R
K
K
S
A
K
G
M
Y
S
C
Site 273
Y4379
K
K
S
A
K
G
M
Y
S
C
P
C
Y
Y
Y
Site 274
Y4384
G
M
Y
S
C
P
C
Y
Y
Y
P
N
R
A
G
Site 275
Y4386
Y
S
C
P
C
Y
Y
Y
P
N
R
A
G
S
S
Site 276
S4392
Y
Y
P
N
R
A
G
S
S
D
R
A
S
F
V
Site 277
S4393
Y
P
N
R
A
G
S
S
D
R
A
S
F
V
I
Site 278
T4410
D
L
R
S
G
A
M
T
P
D
H
W
I
K
R
Site 279
T4419
D
H
W
I
K
R
G
T
A
L
L
M
S
L
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation