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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
STIM2
Full Name:
Stromal interaction molecule 2
Alias:
stromal interaction molecule 2
Type:
Adhesion
Mass (Da):
83971
Number AA:
746
UniProt ID:
Q9P246
International Prot ID:
IPI00001727
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005246
GO:0005509
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0032237
GO:0006816
GO:0006874
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y235
V
G
G
C
W
F
A
Y
T
Q
N
K
T
S
K
Site 2
S254
K
M
M
K
D
L
E
S
L
Q
T
A
E
Q
S
Site 3
T257
K
D
L
E
S
L
Q
T
A
E
Q
S
L
M
D
Site 4
S316
E
G
A
E
C
E
L
S
R
R
Q
Y
A
E
Q
Site 5
Y320
C
E
L
S
R
R
Q
Y
A
E
Q
E
L
E
Q
Site 6
S343
E
K
E
F
E
L
R
S
S
W
S
V
P
D
A
Site 7
S344
K
E
F
E
L
R
S
S
W
S
V
P
D
A
L
Site 8
S346
F
E
L
R
S
S
W
S
V
P
D
A
L
Q
K
Site 9
T358
L
Q
K
W
L
Q
L
T
H
E
V
E
V
Q
Y
Site 10
Y366
H
E
V
E
V
Q
Y
Y
N
I
K
R
Q
N
A
Site 11
S392
E
K
I
K
K
K
R
S
T
V
F
G
T
L
H
Site 12
T393
K
I
K
K
K
R
S
T
V
F
G
T
L
H
V
Site 13
T397
K
R
S
T
V
F
G
T
L
H
V
A
H
S
S
Site 14
S403
G
T
L
H
V
A
H
S
S
S
L
D
E
V
D
Site 15
S405
L
H
V
A
H
S
S
S
L
D
E
V
D
H
K
Site 16
T425
K
A
L
S
E
L
T
T
C
L
R
E
R
L
F
Site 17
S449
G
F
Q
I
A
H
N
S
G
L
P
S
L
T
S
Site 18
S453
A
H
N
S
G
L
P
S
L
T
S
S
L
Y
S
Site 19
T455
N
S
G
L
P
S
L
T
S
S
L
Y
S
D
H
Site 20
S456
S
G
L
P
S
L
T
S
S
L
Y
S
D
H
S
Site 21
S457
G
L
P
S
L
T
S
S
L
Y
S
D
H
S
W
Site 22
Y459
P
S
L
T
S
S
L
Y
S
D
H
S
W
V
V
Site 23
S460
S
L
T
S
S
L
Y
S
D
H
S
W
V
V
M
Site 24
S463
S
S
L
Y
S
D
H
S
W
V
V
M
P
R
V
Site 25
T488
V
D
D
L
D
E
D
T
P
P
I
V
S
Q
F
Site 26
S493
E
D
T
P
P
I
V
S
Q
F
P
G
T
M
A
Site 27
T498
I
V
S
Q
F
P
G
T
M
A
K
P
P
G
S
Site 28
S505
T
M
A
K
P
P
G
S
L
A
R
S
S
S
L
Site 29
S509
P
P
G
S
L
A
R
S
S
S
L
C
R
S
R
Site 30
S510
P
G
S
L
A
R
S
S
S
L
C
R
S
R
R
Site 31
S511
G
S
L
A
R
S
S
S
L
C
R
S
R
R
S
Site 32
S515
R
S
S
S
L
C
R
S
R
R
S
I
V
P
S
Site 33
S518
S
L
C
R
S
R
R
S
I
V
P
S
S
P
Q
Site 34
S522
S
R
R
S
I
V
P
S
S
P
Q
P
Q
R
A
Site 35
S523
R
R
S
I
V
P
S
S
P
Q
P
Q
R
A
Q
Site 36
T550
H
P
H
H
P
Q
H
T
P
H
S
L
P
S
P
Site 37
S553
H
P
Q
H
T
P
H
S
L
P
S
P
D
P
D
Site 38
S556
H
T
P
H
S
L
P
S
P
D
P
D
I
L
S
Site 39
S565
D
P
D
I
L
S
V
S
S
C
P
A
L
Y
R
Site 40
S566
P
D
I
L
S
V
S
S
C
P
A
L
Y
R
N
Site 41
Y581
E
E
E
E
E
A
I
Y
F
S
A
E
K
Q
W
Site 42
S583
E
E
E
A
I
Y
F
S
A
E
K
Q
W
E
V
Site 43
T593
K
Q
W
E
V
P
D
T
A
S
E
C
D
S
L
Site 44
S595
W
E
V
P
D
T
A
S
E
C
D
S
L
N
S
Site 45
S599
D
T
A
S
E
C
D
S
L
N
S
S
I
G
R
Site 46
S602
S
E
C
D
S
L
N
S
S
I
G
R
K
Q
S
Site 47
S603
E
C
D
S
L
N
S
S
I
G
R
K
Q
S
P
Site 48
S609
S
S
I
G
R
K
Q
S
P
P
L
S
L
E
I
Site 49
S613
R
K
Q
S
P
P
L
S
L
E
I
Y
Q
T
L
Site 50
Y617
P
P
L
S
L
E
I
Y
Q
T
L
S
P
R
K
Site 51
T619
L
S
L
E
I
Y
Q
T
L
S
P
R
K
I
S
Site 52
S621
L
E
I
Y
Q
T
L
S
P
R
K
I
S
R
D
Site 53
S626
T
L
S
P
R
K
I
S
R
D
E
V
S
L
E
Site 54
S631
K
I
S
R
D
E
V
S
L
E
D
S
S
R
G
Site 55
S635
D
E
V
S
L
E
D
S
S
R
G
D
S
P
V
Site 56
S636
E
V
S
L
E
D
S
S
R
G
D
S
P
V
T
Site 57
S640
E
D
S
S
R
G
D
S
P
V
T
V
D
V
S
Site 58
T643
S
R
G
D
S
P
V
T
V
D
V
S
W
G
S
Site 59
S661
V
G
L
T
E
T
K
S
M
I
F
S
P
A
S
Site 60
S665
E
T
K
S
M
I
F
S
P
A
S
K
V
Y
N
Site 61
S678
Y
N
G
I
L
E
K
S
C
S
M
N
Q
L
S
Site 62
S680
G
I
L
E
K
S
C
S
M
N
Q
L
S
S
G
Site 63
S685
S
C
S
M
N
Q
L
S
S
G
I
P
V
P
K
Site 64
S686
C
S
M
N
Q
L
S
S
G
I
P
V
P
K
P
Site 65
T696
P
V
P
K
P
R
H
T
S
C
S
S
A
G
N
Site 66
S697
V
P
K
P
R
H
T
S
C
S
S
A
G
N
D
Site 67
S699
K
P
R
H
T
S
C
S
S
A
G
N
D
S
K
Site 68
S700
P
R
H
T
S
C
S
S
A
G
N
D
S
K
P
Site 69
S705
C
S
S
A
G
N
D
S
K
P
V
Q
E
A
P
Site 70
S713
K
P
V
Q
E
A
P
S
V
A
R
I
S
S
I
Site 71
S719
P
S
V
A
R
I
S
S
I
P
H
D
L
C
H
Site 72
S731
L
C
H
N
G
E
K
S
K
K
P
S
K
I
K
Site 73
S735
G
E
K
S
K
K
P
S
K
I
K
S
L
F
K
Site 74
S739
K
K
P
S
K
I
K
S
L
F
K
K
K
S
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation