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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RCC2
Full Name:
Protein RCC2
Alias:
DKFZp762N0610; KIAA1470; RCC1-like TD-60; Regulator of chromosome condensation 2; TD-60
Type:
Guanine nucleotide exchange factor, misc.
Mass (Da):
56085
Number AA:
522
UniProt ID:
Q9P258
International Prot ID:
IPI00465044
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000775
GO:0005874
GO:0005730
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
A
A
W
E
E
P
S
S
G
N
G
T
A
R
A
Site 2
T20
E
P
S
S
G
N
G
T
A
R
A
G
P
R
K
Site 3
S43
R
E
R
P
E
R
C
S
S
S
S
G
G
G
S
Site 4
S44
E
R
P
E
R
C
S
S
S
S
G
G
G
S
S
Site 5
S45
R
P
E
R
C
S
S
S
S
G
G
G
S
S
G
Site 6
S46
P
E
R
C
S
S
S
S
G
G
G
S
S
G
D
Site 7
S50
S
S
S
S
G
G
G
S
S
G
D
E
D
G
L
Site 8
S51
S
S
S
G
G
G
S
S
G
D
E
D
G
L
E
Site 9
T74
K
R
A
A
R
P
A
T
A
G
K
A
G
G
A
Site 10
T91
V
I
T
E
P
E
H
T
K
E
R
V
K
L
E
Site 11
Y142
N
L
W
G
P
H
R
Y
G
C
L
A
G
V
R
Site 12
S173
T
T
E
G
K
L
W
S
W
G
R
N
E
K
G
Site 13
T187
G
Q
L
G
H
G
D
T
K
R
V
E
A
P
R
Site 14
T214
A
A
C
G
R
N
H
T
L
A
L
T
E
T
G
Site 15
T218
R
N
H
T
L
A
L
T
E
T
G
S
V
F
A
Site 16
S245
N
Q
T
D
A
V
P
S
P
A
Q
I
M
Y
N
Site 17
Y276
M
D
C
K
G
N
L
Y
S
F
G
C
P
E
Y
Site 18
S277
D
C
K
G
N
L
Y
S
F
G
C
P
E
Y
G
Site 19
Y283
Y
S
F
G
C
P
E
Y
G
Q
L
G
H
N
S
Site 20
S290
Y
G
Q
L
G
H
N
S
D
G
K
F
I
A
R
Site 21
Y303
A
R
A
Q
R
I
E
Y
D
C
E
L
V
P
R
Site 22
T342
V
A
C
G
A
N
H
T
L
V
L
D
S
Q
K
Site 23
S347
N
H
T
L
V
L
D
S
Q
K
R
V
F
S
W
Site 24
S353
D
S
Q
K
R
V
F
S
W
G
F
G
G
Y
G
Site 25
Y359
F
S
W
G
F
G
G
Y
G
R
L
G
H
A
E
Site 26
S387
D
F
P
G
R
G
A
S
Q
I
Y
A
G
Y
T
Site 27
S417
A
T
N
T
S
R
E
S
T
M
Y
P
K
A
V
Site 28
T418
T
N
T
S
R
E
S
T
M
Y
P
K
A
V
Q
Site 29
Y420
T
S
R
E
S
T
M
Y
P
K
A
V
Q
D
L
Site 30
S434
L
C
G
W
R
I
R
S
L
A
C
G
K
S
S
Site 31
T450
I
V
A
A
D
E
S
T
I
S
W
G
P
S
P
Site 32
S452
A
A
D
E
S
T
I
S
W
G
P
S
P
T
F
Site 33
S456
S
T
I
S
W
G
P
S
P
T
F
G
E
L
G
Site 34
T458
I
S
W
G
P
S
P
T
F
G
E
L
G
Y
G
Site 35
Y464
P
T
F
G
E
L
G
Y
G
D
H
K
P
K
S
Site 36
S471
Y
G
D
H
K
P
K
S
S
T
A
A
Q
E
V
Site 37
T473
D
H
K
P
K
S
S
T
A
A
Q
E
V
K
T
Site 38
S486
K
T
L
D
G
I
F
S
E
Q
V
A
M
G
Y
Site 39
S504
L
V
I
A
R
D
E
S
E
T
E
K
E
K
I
Site 40
Y517
K
I
K
K
L
P
E
Y
N
P
R
T
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation