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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FNIP2
Full Name:
Folliculin-interacting protein 2
Alias:
Type:
Mass (Da):
122115
Number AA:
1114
UniProt ID:
Q9P278
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
K
L
F
N
K
R
G
S
S
G
S
S
A
A
A
Site 2
S16
L
F
N
K
R
G
S
S
G
S
S
A
A
A
S
Site 3
S18
N
K
R
G
S
S
G
S
S
A
A
A
S
A
Q
Site 4
S19
K
R
G
S
S
G
S
S
A
A
A
S
A
Q
G
Site 5
S23
S
G
S
S
A
A
A
S
A
Q
G
R
A
P
K
Site 6
S36
P
K
E
G
P
A
F
S
W
S
C
S
E
F
D
Site 7
S38
E
G
P
A
F
S
W
S
C
S
E
F
D
L
N
Site 8
S40
P
A
F
S
W
S
C
S
E
F
D
L
N
E
I
Site 9
S66
G
R
Q
V
L
F
D
S
K
A
V
Q
K
I
E
Site 10
S95
S
A
K
C
C
Q
G
S
S
S
V
S
S
S
S
Site 11
S96
A
K
C
C
Q
G
S
S
S
V
S
S
S
S
S
Site 12
S97
K
C
C
Q
G
S
S
S
V
S
S
S
S
S
S
Site 13
S99
C
Q
G
S
S
S
V
S
S
S
S
S
S
S
I
Site 14
S100
Q
G
S
S
S
V
S
S
S
S
S
S
S
I
S
Site 15
S101
G
S
S
S
V
S
S
S
S
S
S
S
I
S
S
Site 16
S102
S
S
S
V
S
S
S
S
S
S
S
I
S
S
H
Site 17
S103
S
S
V
S
S
S
S
S
S
S
I
S
S
H
S
Site 18
S104
S
V
S
S
S
S
S
S
S
I
S
S
H
S
S
Site 19
S105
V
S
S
S
S
S
S
S
I
S
S
H
S
S
S
Site 20
S107
S
S
S
S
S
S
I
S
S
H
S
S
S
G
G
Site 21
S108
S
S
S
S
S
I
S
S
H
S
S
S
G
G
S
Site 22
S110
S
S
S
I
S
S
H
S
S
S
G
G
S
S
H
Site 23
S111
S
S
I
S
S
H
S
S
S
G
G
S
S
H
H
Site 24
S112
S
I
S
S
H
S
S
S
G
G
S
S
H
H
A
Site 25
S115
S
H
S
S
S
G
G
S
S
H
H
A
K
E
Q
Site 26
S116
H
S
S
S
G
G
S
S
H
H
A
K
E
Q
L
Site 27
Y126
A
K
E
Q
L
P
K
Y
Q
Y
T
R
P
A
S
Site 28
Y128
E
Q
L
P
K
Y
Q
Y
T
R
P
A
S
D
V
Site 29
S133
Y
Q
Y
T
R
P
A
S
D
V
N
M
L
G
E
Site 30
Y159
G
S
T
L
K
I
H
Y
I
R
S
P
P
Q
L
Site 31
S162
L
K
I
H
Y
I
R
S
P
P
Q
L
M
I
S
Site 32
S178
V
F
S
A
R
M
G
S
F
C
G
S
T
N
N
Site 33
S182
R
M
G
S
F
C
G
S
T
N
N
L
Q
D
S
Site 34
S189
S
T
N
N
L
Q
D
S
F
E
Y
I
N
Q
D
Site 35
T204
P
N
L
G
K
L
N
T
N
Q
N
S
L
G
P
Site 36
S208
K
L
N
T
N
Q
N
S
L
G
P
C
R
T
G
Site 37
T214
N
S
L
G
P
C
R
T
G
S
N
L
A
H
S
Site 38
S216
L
G
P
C
R
T
G
S
N
L
A
H
S
T
P
Site 39
T222
G
S
N
L
A
H
S
T
P
V
D
M
P
S
R
Site 40
S237
G
Q
N
E
D
R
D
S
G
I
A
R
S
A
S
Site 41
S242
R
D
S
G
I
A
R
S
A
S
L
S
S
L
L
Site 42
S255
L
L
I
T
P
F
P
S
P
S
S
S
T
S
S
Site 43
S257
I
T
P
F
P
S
P
S
S
S
T
S
S
S
S
Site 44
S258
T
P
F
P
S
P
S
S
S
T
S
S
S
S
S
Site 45
S259
P
F
P
S
P
S
S
S
T
S
S
S
S
S
Y
Site 46
T260
F
P
S
P
S
S
S
T
S
S
S
S
S
Y
Q
Site 47
S261
P
S
P
S
S
S
T
S
S
S
S
S
Y
Q
R
Site 48
S262
S
P
S
S
S
T
S
S
S
S
S
Y
Q
R
R
Site 49
S263
P
S
S
S
T
S
S
S
S
S
Y
Q
R
R
W
Site 50
S264
S
S
S
T
S
S
S
S
S
Y
Q
R
R
W
L
Site 51
S265
S
S
T
S
S
S
S
S
Y
Q
R
R
W
L
R
Site 52
Y266
S
T
S
S
S
S
S
Y
Q
R
R
W
L
R
S
Site 53
S273
Y
Q
R
R
W
L
R
S
Q
T
T
S
L
E
N
Site 54
T275
R
R
W
L
R
S
Q
T
T
S
L
E
N
G
I
Site 55
S277
W
L
R
S
Q
T
T
S
L
E
N
G
I
I
P
Site 56
S287
N
G
I
I
P
R
R
S
T
D
E
T
F
S
L
Site 57
T288
G
I
I
P
R
R
S
T
D
E
T
F
S
L
A
Site 58
T291
P
R
R
S
T
D
E
T
F
S
L
A
E
E
T
Site 59
S293
R
S
T
D
E
T
F
S
L
A
E
E
T
C
S
Site 60
S300
S
L
A
E
E
T
C
S
S
N
P
A
M
V
R
Site 61
S301
L
A
E
E
T
C
S
S
N
P
A
M
V
R
R
Site 62
S342
S
H
F
P
L
F
E
S
H
M
N
R
L
K
S
Site 63
S349
S
H
M
N
R
L
K
S
A
I
E
K
A
M
I
Site 64
S364
S
C
R
K
I
A
E
S
S
L
R
V
Q
F
Y
Site 65
S365
C
R
K
I
A
E
S
S
L
R
V
Q
F
Y
V
Site 66
Y371
S
S
L
R
V
Q
F
Y
V
S
R
L
M
E
A
Site 67
Y390
R
G
T
I
W
N
L
Y
S
V
P
R
I
A
E
Site 68
S391
G
T
I
W
N
L
Y
S
V
P
R
I
A
E
P
Site 69
S464
H
P
P
I
K
A
F
S
E
K
R
T
S
Q
S
Site 70
S469
A
F
S
E
K
R
T
S
Q
S
V
N
M
L
A
Site 71
S471
S
E
K
R
T
S
Q
S
V
N
M
L
A
K
T
Site 72
T478
S
V
N
M
L
A
K
T
H
P
Y
N
P
L
W
Site 73
S497
D
L
Y
G
A
I
G
S
P
V
R
L
T
R
T
Site 74
T504
S
P
V
R
L
T
R
T
V
V
V
G
K
Q
K
Site 75
S528
L
T
Y
F
L
R
C
S
E
L
Q
E
N
Q
L
Site 76
T536
E
L
Q
E
N
Q
L
T
W
S
G
N
H
G
E
Site 77
S565
E
K
G
E
V
E
E
S
E
Y
V
V
I
T
V
Site 78
Y567
G
E
V
E
E
S
E
Y
V
V
I
T
V
R
N
Site 79
T571
E
S
E
Y
V
V
I
T
V
R
N
E
P
A
L
Site 80
T586
V
P
P
I
L
P
P
T
A
A
E
R
H
N
P
Site 81
T596
E
R
H
N
P
W
P
T
G
F
P
E
C
P
E
Site 82
S607
E
C
P
E
G
T
D
S
R
D
L
G
L
K
P
Site 83
S626
N
R
R
P
E
Q
G
S
E
A
C
S
A
G
C
Site 84
S630
E
Q
G
S
E
A
C
S
A
G
C
L
G
P
A
Site 85
S638
A
G
C
L
G
P
A
S
D
A
S
W
K
P
Q
Site 86
S641
L
G
P
A
S
D
A
S
W
K
P
Q
N
A
F
Site 87
S662
K
E
A
P
Q
D
G
S
S
R
L
P
S
C
E
Site 88
S663
E
A
P
Q
D
G
S
S
R
L
P
S
C
E
V
Site 89
S667
D
G
S
S
R
L
P
S
C
E
V
L
G
A
G
Site 90
S698
P
T
R
L
P
D
R
S
V
A
W
P
C
P
D
Site 91
S713
R
H
L
R
E
K
P
S
L
E
K
V
T
F
Q
Site 92
T718
K
P
S
L
E
K
V
T
F
Q
I
G
S
F
A
Site 93
S723
K
V
T
F
Q
I
G
S
F
A
S
P
E
S
D
Site 94
S726
F
Q
I
G
S
F
A
S
P
E
S
D
F
E
S
Site 95
S729
G
S
F
A
S
P
E
S
D
F
E
S
R
M
K
Site 96
S733
S
P
E
S
D
F
E
S
R
M
K
K
M
E
E
Site 97
S748
R
V
K
A
C
G
P
S
L
E
A
S
E
A
A
Site 98
S752
C
G
P
S
L
E
A
S
E
A
A
D
V
A
Q
Site 99
S766
Q
D
P
Q
V
S
R
S
P
F
K
P
G
F
Q
Site 100
S784
C
C
P
Q
N
R
L
S
E
G
D
E
G
E
S
Site 101
S791
S
E
G
D
E
G
E
S
D
K
G
F
A
E
D
Site 102
S801
G
F
A
E
D
R
G
S
R
N
D
M
A
A
D
Site 103
T821
S
H
A
A
D
L
G
T
A
S
H
G
A
G
G
Site 104
S823
A
A
D
L
G
T
A
S
H
G
A
G
G
T
G
Site 105
T837
G
G
R
R
L
E
A
T
R
G
L
Y
V
K
A
Site 106
Y841
L
E
A
T
R
G
L
Y
V
K
A
A
E
G
P
Site 107
S892
G
D
I
P
R
N
E
S
S
D
S
A
L
G
D
Site 108
S893
D
I
P
R
N
E
S
S
D
S
A
L
G
D
S
Site 109
S895
P
R
N
E
S
S
D
S
A
L
G
D
S
D
D
Site 110
S900
S
D
S
A
L
G
D
S
D
D
E
A
C
A
S
Site 111
S907
S
D
D
E
A
C
A
S
A
M
L
D
L
G
H
Site 112
T919
L
G
H
G
G
D
R
T
G
G
S
L
E
V
E
Site 113
S922
G
G
D
R
T
G
G
S
L
E
V
E
L
P
L
Site 114
S932
V
E
L
P
L
P
R
S
Q
S
I
S
T
Q
N
Site 115
S934
L
P
L
P
R
S
Q
S
I
S
T
Q
N
V
R
Site 116
S936
L
P
R
S
Q
S
I
S
T
Q
N
V
R
N
F
Site 117
S946
N
V
R
N
F
G
R
S
L
L
A
G
Y
C
P
Site 118
T964
P
D
L
V
L
H
G
T
G
S
D
E
K
L
K
Site 119
S966
L
V
L
H
G
T
G
S
D
E
K
L
K
Q
C
Site 120
S1005
I
A
D
T
D
K
W
S
V
Q
V
A
T
S
Q
Site 121
S1011
W
S
V
Q
V
A
T
S
Q
R
K
V
T
D
N
Site 122
T1016
A
T
S
Q
R
K
V
T
D
N
M
K
L
G
Q
Site 123
Y1063
E
D
R
L
Q
E
M
Y
L
K
S
K
M
L
S
Site 124
S1066
L
Q
E
M
Y
L
K
S
K
M
L
S
E
Y
L
Site 125
S1070
Y
L
K
S
K
M
L
S
E
Y
L
R
G
H
T
Site 126
Y1072
K
S
K
M
L
S
E
Y
L
R
G
H
T
R
V
Site 127
T1077
S
E
Y
L
R
G
H
T
R
V
H
V
K
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation