PhosphoNET

           
Protein Info 
   
Short Name:  BCCIP
Full Name:  BRCA2 and CDKN1A-interacting protein
Alias:  BCCIPalpha; BCCIPbeta; BRCA2 and CDKN1A interacting; BRCA2 and CDKN1A interacting protein; cdk inhibitor p21 binding; TOK-1; TOK-1alpha; TOK-1beta
Type:  Cell cycle regulation
Mass (Da):  35979
Number AA:  314
UniProt ID:  Q9P287
International Prot ID:  IPI00002203
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0019908  GO:0005634  GO:0019908 Uniprot OncoNet
Molecular Function:  GO:0019207  GO:0005515  GO:0019207 PhosphoSite+ KinaseNET
Biological Process:  GO:0006281  GO:0007049  GO:0000079 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S5___MASRSKRRAVES
Site 2S12SKRRAVESGVPQPPD
Site 3S42EDEDDDDSDKEKDEE
Site 4Y64VNIEFEAYSLSDNDY
Site 5S65NIEFEAYSLSDNDYD
Site 6S67EFEAYSLSDNDYDGI
Site 7Y71YSLSDNDYDGIKKLL
Site 8T109IGSVIKQTDVSEDSN
Site 9S112VIKQTDVSEDSNDDM
Site 10S115QTDVSEDSNDDMDED
Site 11T134FISLLNLTERKGTQC
Site 12T139NLTERKGTQCVEQIQ
Site 13T172LDKFLNDTTKPVGLL
Site 14T173DKFLNDTTKPVGLLL
Site 15Y196PQIALPMYQQLQKEL
Site 16T209ELAGAHRTNKPCGKC
Site 17Y217NKPCGKCYFYLLISK
Site 18S234VEAGKNNSKKKPSNK
Site 19Y257NAEEEFFYEKAILKF
Site 20Y266KAILKFNYSVQEESD
Site 21S267AILKFNYSVQEESDT
Site 22S272NYSVQEESDTCLGGK
Site 23T274SVQEESDTCLGGKWS
Site 24S281TCLGGKWSFDDVPMT
Site 25Y311IMDKLKEYLSV____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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