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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABI3
Full Name:
ABI gene family member 3
Alias:
ABI family, member 3; ABI gene family 3; NESH; New molecule including SH3; SSH3BP3
Type:
Adaptor/scaffold
Mass (Da):
38975
Number AA:
366
UniProt ID:
Q9P2A4
International Prot ID:
IPI00009273
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0030027
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006928
GO:0030334
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y32
A
L
L
R
V
A
D
Y
C
E
D
N
Y
V
Q
Site 2
Y37
A
D
Y
C
E
D
N
Y
V
Q
A
T
D
K
R
Site 3
S91
R
Q
V
E
A
R
V
S
T
L
G
Q
M
V
N
Site 4
T114
R
E
I
G
T
L
A
T
V
Q
R
L
P
P
G
Site 5
T134
P
E
N
L
P
P
L
T
P
Y
C
R
R
P
L
Site 6
Y136
N
L
P
P
L
T
P
Y
C
R
R
P
L
N
F
Site 7
S157
G
H
G
I
K
D
L
S
T
Q
L
S
R
T
G
Site 8
T158
H
G
I
K
D
L
S
T
Q
L
S
R
T
G
T
Site 9
S161
K
D
L
S
T
Q
L
S
R
T
G
T
L
S
R
Site 10
T165
T
Q
L
S
R
T
G
T
L
S
R
K
S
I
K
Site 11
S167
L
S
R
T
G
T
L
S
R
K
S
I
K
A
P
Site 12
S170
T
G
T
L
S
R
K
S
I
K
A
P
A
T
P
Site 13
T176
K
S
I
K
A
P
A
T
P
A
S
A
T
L
G
Site 14
S179
K
A
P
A
T
P
A
S
A
T
L
G
R
P
P
Site 15
T181
P
A
T
P
A
S
A
T
L
G
R
P
P
R
I
Site 16
S203
V
V
P
D
G
R
L
S
A
A
S
S
A
S
S
Site 17
S206
D
G
R
L
S
A
A
S
S
A
S
S
L
A
S
Site 18
T225
E
G
V
G
G
A
P
T
P
K
G
Q
A
A
P
Site 19
S239
P
P
A
P
P
L
P
S
S
L
D
P
P
P
P
Site 20
S240
P
A
P
P
L
P
S
S
L
D
P
P
P
P
P
Site 21
T258
E
V
F
Q
R
P
P
T
L
E
E
L
S
P
P
Site 22
S263
P
P
T
L
E
E
L
S
P
P
P
P
D
E
E
Site 23
S303
G
F
G
P
D
E
P
S
W
V
P
A
S
Y
L
Site 24
S308
E
P
S
W
V
P
A
S
Y
L
E
K
V
V
T
Site 25
T315
S
Y
L
E
K
V
V
T
L
Y
P
Y
T
S
Q
Site 26
Y317
L
E
K
V
V
T
L
Y
P
Y
T
S
Q
K
D
Site 27
S321
V
T
L
Y
P
Y
T
S
Q
K
D
N
E
L
S
Site 28
S328
S
Q
K
D
N
E
L
S
F
S
E
G
T
V
I
Site 29
S330
K
D
N
E
L
S
F
S
E
G
T
V
I
C
V
Site 30
Y341
V
I
C
V
T
R
R
Y
S
D
G
W
C
E
G
Site 31
S350
D
G
W
C
E
G
V
S
S
E
G
T
G
F
F
Site 32
S351
G
W
C
E
G
V
S
S
E
G
T
G
F
F
P
Site 33
T354
E
G
V
S
S
E
G
T
G
F
F
P
G
N
Y
Site 34
Y361
T
G
F
F
P
G
N
Y
V
E
P
S
C
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation