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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNFX1
Full Name:
NFX1-type zinc finger-containing protein 1
Alias:
Type:
Mass (Da):
220209
Number AA:
1918
UniProt ID:
Q9P2E3
International Prot ID:
IPI00165981
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0005737
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003676
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0006082
GO:0006139
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
L
D
A
R
P
R
N
S
H
T
N
H
R
G
P
Site 2
T17
A
R
P
R
N
S
H
T
N
H
R
G
P
V
D
Site 3
S48
N
A
L
R
G
G
A
S
H
P
G
R
H
P
R
Site 4
Y63
A
N
N
H
P
A
A
Y
W
Q
R
E
E
R
F
Site 5
S89
R
N
Q
E
G
H
A
S
D
E
A
R
D
Q
R
Site 6
T129
D
N
F
Q
Q
W
R
T
P
H
Q
K
P
T
E
Site 7
T135
R
T
P
H
Q
K
P
T
E
Q
P
Q
Q
A
K
Site 8
S151
L
G
Y
K
F
L
E
S
L
L
Q
K
D
P
S
Site 9
S175
L
G
L
K
E
L
L
S
H
S
S
M
K
S
N
Site 10
S177
L
K
E
L
L
S
H
S
S
M
K
S
N
F
L
Site 11
S196
Q
V
L
R
K
A
C
S
S
K
M
D
R
Q
S
Site 12
S197
V
L
R
K
A
C
S
S
K
M
D
R
Q
S
V
Site 13
S203
S
S
K
M
D
R
Q
S
V
L
H
V
L
G
I
Site 14
Y240
I
P
D
I
R
N
Q
Y
P
E
H
I
S
N
I
Site 15
S245
N
Q
Y
P
E
H
I
S
N
I
I
S
L
L
Q
Site 16
S283
S
L
N
A
L
R
A
S
G
V
D
I
E
E
E
Site 17
T300
K
N
L
E
K
V
Q
T
I
I
E
H
L
Q
E
Site 18
T313
Q
E
K
R
R
E
G
T
L
R
V
D
T
Y
T
Site 19
T318
E
G
T
L
R
V
D
T
Y
T
L
V
Q
P
E
Site 20
Y319
G
T
L
R
V
D
T
Y
T
L
V
Q
P
E
A
Site 21
T320
T
L
R
V
D
T
Y
T
L
V
Q
P
E
A
E
Site 22
T335
D
H
V
E
S
Y
R
T
M
P
I
Y
P
T
Y
Site 23
Y339
S
Y
R
T
M
P
I
Y
P
T
Y
N
E
V
H
Site 24
Y342
T
M
P
I
Y
P
T
Y
N
E
V
H
L
D
E
Site 25
S359
F
L
R
P
N
I
I
S
G
K
Y
D
S
T
A
Site 26
Y362
P
N
I
I
S
G
K
Y
D
S
T
A
I
Y
L
Site 27
Y368
K
Y
D
S
T
A
I
Y
L
D
T
H
F
R
L
Site 28
T371
S
T
A
I
Y
L
D
T
H
F
R
L
L
R
E
Site 29
S394
G
I
L
E
L
L
Q
S
F
E
D
Q
G
L
R
Site 30
Y411
K
F
D
D
I
R
I
Y
F
D
T
R
I
I
T
Site 31
T418
Y
F
D
T
R
I
I
T
P
M
C
S
S
S
G
Site 32
Y428
C
S
S
S
G
I
V
Y
K
V
Q
F
D
T
K
Site 33
S445
K
F
V
R
W
Q
N
S
K
R
L
L
Y
G
S
Site 34
Y450
Q
N
S
K
R
L
L
Y
G
S
L
V
C
M
S
Site 35
S452
S
K
R
L
L
Y
G
S
L
V
C
M
S
K
D
Site 36
T468
F
E
T
F
L
F
A
T
V
S
N
R
E
Q
E
Site 37
S470
T
F
L
F
A
T
V
S
N
R
E
Q
E
D
L
Site 38
S502
A
E
V
Q
P
S
D
S
F
L
M
V
E
T
T
Site 39
Y548
S
H
V
K
E
P
R
Y
L
L
M
G
G
R
Y
Site 40
T558
M
G
G
R
Y
D
F
T
P
L
I
E
N
P
S
Site 41
S592
L
D
P
G
Q
W
P
S
K
E
A
L
K
L
D
Site 42
S601
E
A
L
K
L
D
D
S
Q
M
E
A
L
Q
F
Site 43
Y627
P
P
G
T
G
K
T
Y
V
G
L
K
I
V
Q
Site 44
S641
Q
A
L
L
T
N
E
S
V
W
Q
I
S
L
Q
Site 45
S646
N
E
S
V
W
Q
I
S
L
Q
K
F
P
I
L
Site 46
Y670
D
Q
F
L
E
G
I
Y
N
C
Q
K
T
S
I
Site 47
T675
G
I
Y
N
C
Q
K
T
S
I
V
R
V
G
G
Site 48
S684
I
V
R
V
G
G
R
S
N
S
E
I
L
K
Q
Site 49
S686
R
V
G
G
R
S
N
S
E
I
L
K
Q
F
T
Site 50
T693
S
E
I
L
K
Q
F
T
L
R
E
L
R
N
K
Site 51
T735
E
L
H
E
G
A
K
T
L
E
C
T
M
R
G
Site 52
T739
G
A
K
T
L
E
C
T
M
R
G
V
L
R
E
Site 53
Y748
R
G
V
L
R
E
Q
Y
L
Q
K
Y
I
S
P
Site 54
Y752
R
E
Q
Y
L
Q
K
Y
I
S
P
Q
H
W
E
Site 55
S754
Q
Y
L
Q
K
Y
I
S
P
Q
H
W
E
S
L
Site 56
S796
G
V
G
S
F
T
Q
S
V
S
P
A
G
P
E
Site 57
S798
G
S
F
T
Q
S
V
S
P
A
G
P
E
N
T
Site 58
S821
E
E
G
E
E
E
S
S
L
I
E
I
A
E
E
Site 59
S854
Q
R
R
K
K
E
E
S
G
A
D
Q
E
L
A
Site 60
Y934
L
S
S
R
W
Q
L
Y
R
L
W
L
Q
L
Y
Site 61
Y941
Y
R
L
W
L
Q
L
Y
Q
A
D
T
R
R
K
Site 62
T945
L
Q
L
Y
Q
A
D
T
R
R
K
I
L
S
Y
Site 63
S951
D
T
R
R
K
I
L
S
Y
E
R
Q
Y
R
T
Site 64
Y952
T
R
R
K
I
L
S
Y
E
R
Q
Y
R
T
S
Site 65
Y956
I
L
S
Y
E
R
Q
Y
R
T
S
A
E
R
M
Site 66
S959
Y
E
R
Q
Y
R
T
S
A
E
R
M
A
E
L
Site 67
S1039
D
H
Q
Q
L
R
P
S
A
N
V
Y
D
L
A
Site 68
Y1043
L
R
P
S
A
N
V
Y
D
L
A
K
N
F
N
Site 69
S1054
K
N
F
N
L
E
V
S
L
F
E
R
L
V
K
Site 70
Y1071
I
P
F
V
R
L
N
Y
Q
H
R
M
C
P
E
Site 71
T1084
P
E
I
A
R
L
L
T
P
H
I
Y
Q
D
L
Site 72
Y1088
R
L
L
T
P
H
I
Y
Q
D
L
E
N
H
P
Site 73
S1096
Q
D
L
E
N
H
P
S
V
L
K
Y
E
K
I
Site 74
Y1100
N
H
P
S
V
L
K
Y
E
K
I
K
G
V
S
Site 75
S1108
E
K
I
K
G
V
S
S
N
L
F
F
V
E
H
Site 76
T1175
R
K
L
M
P
A
K
T
F
A
G
V
R
V
H
Site 77
Y1187
R
V
H
V
V
D
K
Y
Q
G
E
E
N
D
I
Site 78
S1198
E
N
D
I
I
L
L
S
L
V
R
S
N
Q
E
Site 79
Y1229
S
R
A
K
K
G
M
Y
C
I
G
N
M
Q
M
Site 80
T1249
L
W
S
K
I
I
H
T
L
R
E
N
N
Q
I
Site 81
T1272
Q
N
H
P
E
T
H
T
L
V
S
K
A
S
D
Site 82
S1289
K
V
P
E
G
G
C
S
L
P
C
E
F
R
L
Site 83
Y1309
C
T
R
A
C
H
P
Y
D
S
S
H
K
E
F
Site 84
T1351
C
Q
V
K
V
P
K
T
I
P
R
C
G
H
E
Site 85
S1411
I
K
L
K
C
G
H
S
Q
P
V
K
C
G
H
Site 86
Y1424
G
H
V
E
G
L
L
Y
G
G
L
L
V
K
C
Site 87
T1432
G
G
L
L
V
K
C
T
T
K
C
G
T
I
L
Site 88
T1433
G
L
L
V
K
C
T
T
K
C
G
T
I
L
D
Site 89
S1472
C
K
R
L
L
I
C
S
H
K
C
Q
E
P
C
Site 90
Y1537
P
C
N
R
P
P
C
Y
V
P
C
T
K
L
L
Site 91
Y1603
E
V
Q
A
L
D
R
Y
M
N
E
Q
K
D
D
Site 92
Y1632
P
I
R
K
N
L
R
Y
G
T
S
I
K
Q
R
Site 93
T1634
R
K
N
L
R
Y
G
T
S
I
K
Q
R
L
E
Site 94
S1660
S
A
G
E
I
A
T
S
Q
E
R
L
K
A
L
Site 95
S1672
K
A
L
L
E
R
K
S
L
L
H
Q
L
L
P
Site 96
Y1709
V
E
N
Y
I
S
F
Y
D
H
L
A
S
L
W
Site 97
S1714
S
F
Y
D
H
L
A
S
L
W
D
S
L
K
K
Site 98
T1732
L
E
E
K
R
V
R
T
R
L
E
Q
V
H
E
Site 99
S1747
W
L
A
K
K
R
L
S
F
T
S
Q
E
L
S
Site 100
S1750
K
K
R
L
S
F
T
S
Q
E
L
S
D
L
R
Site 101
S1754
S
F
T
S
Q
E
L
S
D
L
R
S
E
I
Q
Site 102
S1758
Q
E
L
S
D
L
R
S
E
I
Q
R
L
T
Y
Site 103
T1764
R
S
E
I
Q
R
L
T
Y
L
V
N
L
L
T
Site 104
Y1765
S
E
I
Q
R
L
T
Y
L
V
N
L
L
T
R
Site 105
S1828
P
C
S
G
L
G
I
S
E
E
E
R
V
Q
I
Site 106
S1837
E
E
R
V
Q
I
V
S
A
I
G
Y
P
R
G
Site 107
Y1841
Q
I
V
S
A
I
G
Y
P
R
G
H
W
F
K
Site 108
Y1855
K
C
R
N
G
H
I
Y
V
I
G
D
C
G
G
Site 109
T1868
G
G
A
M
E
R
G
T
C
P
D
C
K
E
V
Site 110
T1882
V
I
G
G
T
N
H
T
L
E
R
S
N
Q
L
Site 111
S1886
T
N
H
T
L
E
R
S
N
Q
L
A
S
E
M
Site 112
S1891
E
R
S
N
Q
L
A
S
E
M
D
G
A
Q
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation