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Updated November 2019
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Protein Info
Short Name:
STOX2
Full Name:
Storkhead-box protein 2
Alias:
DKFZp762K222; KIAA1392; Storkhead box 2
Type:
Unknown function
Mass (Da):
102671
Number AA:
926
UniProt ID:
Q9P2F5
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
K
K
T
R
S
T
T
L
R
R
A
W
P
Site 2
T8
M
K
K
T
R
S
T
T
L
R
R
A
W
P
S
Site 3
S15
T
L
R
R
A
W
P
S
S
D
F
S
D
R
A
Site 4
S16
L
R
R
A
W
P
S
S
D
F
S
D
R
A
S
Site 5
S19
A
W
P
S
S
D
F
S
D
R
A
S
D
R
M
Site 6
S23
S
D
F
S
D
R
A
S
D
R
M
R
S
R
S
Site 7
S28
R
A
S
D
R
M
R
S
R
S
E
K
D
Y
R
Site 8
S30
S
D
R
M
R
S
R
S
E
K
D
Y
R
L
H
Site 9
Y34
R
S
R
S
E
K
D
Y
R
L
H
K
R
F
P
Site 10
Y52
A
P
Q
A
S
R
G
Y
M
T
S
G
D
V
S
Site 11
S55
A
S
R
G
Y
M
T
S
G
D
V
S
P
I
S
Site 12
S62
S
G
D
V
S
P
I
S
M
S
P
I
S
Q
S
Site 13
S64
D
V
S
P
I
S
M
S
P
I
S
Q
S
Q
F
Site 14
S69
S
M
S
P
I
S
Q
S
Q
F
I
P
L
G
E
Site 15
S87
L
A
I
S
A
M
N
S
A
R
K
P
V
T
Q
Site 16
T110
T
C
F
P
G
V
P
T
P
S
Q
E
I
L
R
Site 17
S112
F
P
G
V
P
T
P
S
Q
E
I
L
R
H
T
Site 18
T119
S
Q
E
I
L
R
H
T
L
N
T
L
V
R
E
Site 19
T122
I
L
R
H
T
L
N
T
L
V
R
E
R
K
I
Site 20
Y130
L
V
R
E
R
K
I
Y
P
T
P
D
G
Y
F
Site 21
T132
R
E
R
K
I
Y
P
T
P
D
G
Y
F
I
V
Site 22
Y136
I
Y
P
T
P
D
G
Y
F
I
V
T
P
Q
T
Site 23
T147
T
P
Q
T
Y
F
I
T
P
S
L
I
R
T
N
Site 24
S149
Q
T
Y
F
I
T
P
S
L
I
R
T
N
S
K
Site 25
T153
I
T
P
S
L
I
R
T
N
S
K
W
Y
H
L
Site 26
S155
P
S
L
I
R
T
N
S
K
W
Y
H
L
D
E
Site 27
S168
D
E
R
I
P
D
R
S
Q
C
T
S
P
Q
P
Site 28
S172
P
D
R
S
Q
C
T
S
P
Q
P
G
T
I
T
Site 29
T177
C
T
S
P
Q
P
G
T
I
T
P
S
A
S
G
Site 30
T179
S
P
Q
P
G
T
I
T
P
S
A
S
G
C
V
Site 31
S181
Q
P
G
T
I
T
P
S
A
S
G
C
V
R
E
Site 32
S183
G
T
I
T
P
S
A
S
G
C
V
R
E
R
T
Site 33
T190
S
G
C
V
R
E
R
T
L
P
R
N
H
C
D
Site 34
T209
C
R
E
D
V
H
S
T
H
A
P
T
L
Q
R
Site 35
T213
V
H
S
T
H
A
P
T
L
Q
R
K
S
A
K
Site 36
S218
A
P
T
L
Q
R
K
S
A
K
D
C
K
D
P
Site 37
Y226
A
K
D
C
K
D
P
Y
C
P
P
S
L
C
Q
Site 38
S230
K
D
P
Y
C
P
P
S
L
C
Q
V
P
P
T
Site 39
T237
S
L
C
Q
V
P
P
T
E
K
S
K
S
T
V
Site 40
S240
Q
V
P
P
T
E
K
S
K
S
T
V
N
F
S
Site 41
S242
P
P
T
E
K
S
K
S
T
V
N
F
S
Y
K
Site 42
T243
P
T
E
K
S
K
S
T
V
N
F
S
Y
K
T
Site 43
S247
S
K
S
T
V
N
F
S
Y
K
T
E
T
L
S
Site 44
S254
S
Y
K
T
E
T
L
S
K
P
K
D
S
E
K
Site 45
S259
T
L
S
K
P
K
D
S
E
K
Q
S
K
K
F
Site 46
S263
P
K
D
S
E
K
Q
S
K
K
F
G
L
K
L
Site 47
S274
G
L
K
L
F
R
L
S
F
K
K
D
K
T
K
Site 48
T280
L
S
F
K
K
D
K
T
K
Q
L
A
N
F
S
Site 49
T302
W
P
L
R
D
E
D
T
P
A
T
I
P
R
E
Site 50
T305
R
D
E
D
T
P
A
T
I
P
R
E
V
E
M
Site 51
T323
R
R
I
N
P
D
L
T
V
E
N
V
M
R
H
Site 52
T331
V
E
N
V
M
R
H
T
A
L
M
K
K
L
E
Site 53
S345
E
E
E
K
A
Q
R
S
K
A
G
S
S
A
H
Site 54
S349
A
Q
R
S
K
A
G
S
S
A
H
H
S
G
R
Site 55
S350
Q
R
S
K
A
G
S
S
A
H
H
S
G
R
S
Site 56
S354
A
G
S
S
A
H
H
S
G
R
S
K
K
S
R
Site 57
S357
S
A
H
H
S
G
R
S
K
K
S
R
T
H
R
Site 58
S360
H
S
G
R
S
K
K
S
R
T
H
R
K
S
H
Site 59
T362
G
R
S
K
K
S
R
T
H
R
K
S
H
G
K
Site 60
S366
K
S
R
T
H
R
K
S
H
G
K
S
R
S
H
Site 61
S370
H
R
K
S
H
G
K
S
R
S
H
S
K
T
R
Site 62
S372
K
S
H
G
K
S
R
S
H
S
K
T
R
V
S
Site 63
S374
H
G
K
S
R
S
H
S
K
T
R
V
S
K
G
Site 64
T376
K
S
R
S
H
S
K
T
R
V
S
K
G
D
P
Site 65
S379
S
H
S
K
T
R
V
S
K
G
D
P
S
D
G
Site 66
S384
R
V
S
K
G
D
P
S
D
G
S
H
L
D
I
Site 67
S387
K
G
D
P
S
D
G
S
H
L
D
I
P
A
E
Site 68
Y397
D
I
P
A
E
R
E
Y
D
F
C
D
P
L
T
Site 69
T404
Y
D
F
C
D
P
L
T
R
V
P
R
E
G
C
Site 70
S425
G
D
N
F
I
M
H
S
N
T
N
V
L
E
S
Site 71
T437
L
E
S
H
F
P
M
T
P
E
W
D
V
S
G
Site 72
S443
M
T
P
E
W
D
V
S
G
E
L
A
K
R
R
Site 73
T451
G
E
L
A
K
R
R
T
E
M
P
F
P
E
P
Site 74
S459
E
M
P
F
P
E
P
S
R
G
S
S
H
S
K
Site 75
S462
F
P
E
P
S
R
G
S
S
H
S
K
V
H
R
Site 76
S463
P
E
P
S
R
G
S
S
H
S
K
V
H
R
S
Site 77
S465
P
S
R
G
S
S
H
S
K
V
H
R
S
H
S
Site 78
S472
S
K
V
H
R
S
H
S
H
T
Q
D
R
R
S
Site 79
T474
V
H
R
S
H
S
H
T
Q
D
R
R
S
R
N
Site 80
S479
S
H
T
Q
D
R
R
S
R
N
E
R
S
N
K
Site 81
S493
K
A
K
E
R
S
R
S
M
D
N
S
K
G
P
Site 82
S497
R
S
R
S
M
D
N
S
K
G
P
L
G
A
S
Site 83
S504
S
K
G
P
L
G
A
S
S
L
G
T
P
E
D
Site 84
S505
K
G
P
L
G
A
S
S
L
G
T
P
E
D
L
Site 85
T508
L
G
A
S
S
L
G
T
P
E
D
L
A
E
G
Site 86
S517
E
D
L
A
E
G
C
S
Q
D
D
Q
T
P
S
Site 87
T522
G
C
S
Q
D
D
Q
T
P
S
Q
S
Y
I
D
Site 88
S524
S
Q
D
D
Q
T
P
S
Q
S
Y
I
D
D
S
Site 89
S526
D
D
Q
T
P
S
Q
S
Y
I
D
D
S
T
L
Site 90
S531
S
Q
S
Y
I
D
D
S
T
L
R
P
A
Q
T
Site 91
T532
Q
S
Y
I
D
D
S
T
L
R
P
A
Q
T
V
Site 92
T538
S
T
L
R
P
A
Q
T
V
S
L
Q
R
A
H
Site 93
S540
L
R
P
A
Q
T
V
S
L
Q
R
A
H
I
S
Site 94
S548
L
Q
R
A
H
I
S
S
T
S
Y
K
E
V
C
Site 95
Y551
A
H
I
S
S
T
S
Y
K
E
V
C
I
P
E
Site 96
S561
V
C
I
P
E
I
V
S
G
S
K
E
P
S
S
Site 97
S563
I
P
E
I
V
S
G
S
K
E
P
S
S
A
C
Site 98
S567
V
S
G
S
K
E
P
S
S
A
C
S
L
L
E
Site 99
S568
S
G
S
K
E
P
S
S
A
C
S
L
L
E
P
Site 100
S571
K
E
P
S
S
A
C
S
L
L
E
P
G
K
P
Site 101
S581
E
P
G
K
P
P
E
S
L
P
S
Y
G
E
L
Site 102
S584
K
P
P
E
S
L
P
S
Y
G
E
L
N
S
C
Site 103
Y585
P
P
E
S
L
P
S
Y
G
E
L
N
S
C
P
Site 104
S590
P
S
Y
G
E
L
N
S
C
P
T
K
T
A
T
Site 105
Y600
T
K
T
A
T
D
D
Y
F
Q
C
N
T
S
S
Site 106
S607
Y
F
Q
C
N
T
S
S
E
T
V
L
T
A
P
Site 107
T612
T
S
S
E
T
V
L
T
A
P
S
P
L
G
K
Site 108
S615
E
T
V
L
T
A
P
S
P
L
G
K
N
K
E
Site 109
T626
K
N
K
E
D
H
D
T
L
T
L
A
E
G
V
Site 110
T628
K
E
D
H
D
T
L
T
L
A
E
G
V
K
K
Site 111
S637
A
E
G
V
K
K
L
S
P
S
D
R
Q
V
P
Site 112
S639
G
V
K
K
L
S
P
S
D
R
Q
V
P
H
S
Site 113
S646
S
D
R
Q
V
P
H
S
S
R
E
P
V
G
H
Site 114
S647
D
R
Q
V
P
H
S
S
R
E
P
V
G
H
K
Site 115
S657
P
V
G
H
K
E
E
S
P
K
G
P
G
G
G
Site 116
S690
H
H
G
A
E
P
S
S
L
D
K
R
K
E
I
Site 117
S699
D
K
R
K
E
I
F
S
K
D
T
L
F
K
P
Site 118
T702
K
E
I
F
S
K
D
T
L
F
K
P
L
H
S
Site 119
S709
T
L
F
K
P
L
H
S
T
L
S
V
N
S
Y
Site 120
T710
L
F
K
P
L
H
S
T
L
S
V
N
S
Y
H
Site 121
S712
K
P
L
H
S
T
L
S
V
N
S
Y
H
K
S
Site 122
S715
H
S
T
L
S
V
N
S
Y
H
K
S
S
L
S
Site 123
Y716
S
T
L
S
V
N
S
Y
H
K
S
S
L
S
L
Site 124
S719
S
V
N
S
Y
H
K
S
S
L
S
L
L
K
S
Site 125
S720
V
N
S
Y
H
K
S
S
L
S
L
L
K
S
H
Site 126
S722
S
Y
H
K
S
S
L
S
L
L
K
S
H
P
K
Site 127
S726
S
S
L
S
L
L
K
S
H
P
K
T
P
A
D
Site 128
T730
L
L
K
S
H
P
K
T
P
A
D
T
L
P
G
Site 129
T734
H
P
K
T
P
A
D
T
L
P
G
R
C
E
K
Site 130
S745
R
C
E
K
L
E
P
S
L
G
T
S
A
A
Q
Site 131
S757
A
A
Q
A
M
P
A
S
Q
R
Q
Q
E
S
G
Site 132
S770
S
G
G
N
Q
E
A
S
F
D
Y
Y
N
V
S
Site 133
Y773
N
Q
E
A
S
F
D
Y
Y
N
V
S
D
D
D
Site 134
Y774
Q
E
A
S
F
D
Y
Y
N
V
S
D
D
D
D
Site 135
S777
S
F
D
Y
Y
N
V
S
D
D
D
D
S
E
E
Site 136
S782
N
V
S
D
D
D
D
S
E
E
G
A
N
K
N
Site 137
T801
K
N
R
E
D
V
G
T
M
Q
W
L
L
E
R
Site 138
T823
R
K
F
E
K
N
L
T
L
L
A
P
K
E
T
Site 139
T830
T
L
L
A
P
K
E
T
D
S
S
S
N
Q
R
Site 140
S833
A
P
K
E
T
D
S
S
S
N
Q
R
A
T
H
Site 141
S834
P
K
E
T
D
S
S
S
N
Q
R
A
T
H
S
Site 142
T839
S
S
S
N
Q
R
A
T
H
S
A
R
L
D
S
Site 143
S841
S
N
Q
R
A
T
H
S
A
R
L
D
S
M
D
Site 144
S846
T
H
S
A
R
L
D
S
M
D
S
S
S
I
T
Site 145
S849
A
R
L
D
S
M
D
S
S
S
I
T
V
D
S
Site 146
S850
R
L
D
S
M
D
S
S
S
I
T
V
D
S
G
Site 147
S851
L
D
S
M
D
S
S
S
I
T
V
D
S
G
F
Site 148
T853
S
M
D
S
S
S
I
T
V
D
S
G
F
N
S
Site 149
S856
S
S
S
I
T
V
D
S
G
F
N
S
P
R
T
Site 150
S860
T
V
D
S
G
F
N
S
P
R
T
R
E
S
L
Site 151
T863
S
G
F
N
S
P
R
T
R
E
S
L
A
S
N
Site 152
S866
N
S
P
R
T
R
E
S
L
A
S
N
T
S
S
Site 153
S869
R
T
R
E
S
L
A
S
N
T
S
S
I
V
E
Site 154
S872
E
S
L
A
S
N
T
S
S
I
V
E
S
N
R
Site 155
S873
S
L
A
S
N
T
S
S
I
V
E
S
N
R
R
Site 156
S877
N
T
S
S
I
V
E
S
N
R
R
Q
N
P
A
Site 157
S886
R
R
Q
N
P
A
L
S
P
A
H
G
G
A
G
Site 158
S901
P
A
F
N
F
R
A
S
A
E
P
P
T
N
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation