PhosphoNET

           
Protein Info 
   
Short Name:  SIPA1L2
Full Name:  Signal-induced proliferation-associated 1-like protein 2
Alias:  KIAA1389; SI1L2; signal-induced proliferation-associated 1 like 2; SIL2
Type:  Unknown function
Mass (Da):  190438
Number AA:  1722
UniProt ID:  Q9P2F8
International Prot ID:  IPI00444572
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005622  GO:0044464   Uniprot OncoNet
Molecular Function:  GO:0005096  GO:0005515  GO:0005515 PhosphoSite+ KinaseNET
Biological Process:  GO:0051056  GO:0050789  GO:0050794 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S7_MSDPRQSQEEKHKL
Site 2S18KHKLGRASSKFKDPP
Site 3S19HKLGRASSKFKDPPR
Site 4S30DPPRIMQSDDYFARK
Site 5Y33RIMQSDDYFARKFKA
Site 6T49NGNMGPTTSLNASNS
Site 7S50GNMGPTTSLNASNSN
Site 8S54PTTSLNASNSNETGG
Site 9S56TSLNASNSNETGGGG
Site 10T68GGGPANGTPAVPKMG
Site 11S81MGVRARVSEWPPKKD
Site 12T94KDCSKELTCKALWES
Site 13S103KALWESRSQTSYESI
Site 14T105LWESRSQTSYESITS
Site 15S106WESRSQTSYESITSV
Site 16Y107ESRSQTSYESITSVL
Site 17S109RSQTSYESITSVLQN
Site 18S112TSYESITSVLQNGQS
Site 19S119SVLQNGQSDQSEGQQ
Site 20S148IGDIFVHSPQRGLHP
Site 21S160LHPIRQRSNSDVTIS
Site 22S162PIRQRSNSDVTISDI
Site 23T165QRSNSDVTISDIDAE
Site 24S167SNSDVTISDIDAEDV
Site 25Y192GAALHREYGSTSSID
Site 26T195LHREYGSTSSIDRQG
Site 27S196HREYGSTSSIDRQGL
Site 28S197REYGSTSSIDRQGLS
Site 29S204SIDRQGLSGENFFAM
Site 30Y215FFAMLRGYRVENYDH
Site 31Y220RGYRVENYDHKAMVP
Site 32S241FRCDPAISPSLHAAA
Site 33S259RGEFVRISGLDYVDS
Site 34Y263VRISGLDYVDSALLM
Site 35S266SGLDYVDSALLMGRD
Site 36S284PFKRRLKSESVETSL
Site 37S286KRRLKSESVETSLFR
Site 38S290KSESVETSLFRKLRT
Site 39T297SLFRKLRTVKSEHET
Site 40S300RKLRTVKSEHETFKF
Site 41T304TVKSEHETFKFTSEL
Site 42T308EHETFKFTSELEESR
Site 43S309HETFKFTSELEESRL
Site 44S314FTSELEESRLERGIR
Site 45T347NINEAMATRANVGKR
Site 46T358VGKRKNITTGASAAS
Site 47T359GKRKNITTGASAASQ
Site 48S365TTGASAASQTQMPTG
Site 49T367GASAASQTQMPTGQT
Site 50S379GQTGNCESPLGSKED
Site 51S383NCESPLGSKEDLNSK
Site 52S389GSKEDLNSKENLDAD
Site 53S402ADEGDGKSNDLVLSC
Site 54S408KSNDLVLSCPYFRNE
Site 55Y411DLVLSCPYFRNETGG
Site 56T416CPYFRNETGGEGDRR
Site 57S427GDRRIALSRANSSSF
Site 58S431IALSRANSSSFSSGE
Site 59S432ALSRANSSSFSSGES
Site 60S433LSRANSSSFSSGESC
Site 61S435RANSSSFSSGESCSF
Site 62S436ANSSSFSSGESCSFE
Site 63S439SSFSSGESCSFESSL
Site 64S441FSSGESCSFESSLSS
Site 65S444GESCSFESSLSSHCT
Site 66S445ESCSFESSLSSHCTN
Site 67S447CSFESSLSSHCTNAG
Site 68S448SFESSLSSHCTNAGV
Site 69Y475HREKVKRYIIEHIDL
Site 70Y485EHIDLGAYYYRKFFY
Site 71Y486HIDLGAYYYRKFFYG
Site 72Y487IDLGAYYYRKFFYGK
Site 73Y499YGKEHQNYFGIDENL
Site 74S512NLGPVAVSIRREKVE
Site 75S527DAKEKEGSQFNYRVA
Site 76Y531KEGSQFNYRVAFRTS
Site 77T537NYRVAFRTSELTTLR
Site 78S538YRVAFRTSELTTLRG
Site 79T542FRTSELTTLRGAILE
Site 80T555LEDAIPSTARHGTAR
Site 81T560PSTARHGTARGLPLK
Site 82S586IQCLRQASNSPKVSE
Site 83S588CLRQASNSPKVSEQL
Site 84S592ASNSPKVSEQLLKLD
Site 85S604KLDEQGLSFQHKIGI
Site 86Y613QHKIGILYCKAGQST
Site 87Y625QSTEEEMYNNETAGP
Site 88S651RVRLKGFSKYRAQLD
Site 89Y653RLKGFSKYRAQLDNK
Site 90T661RAQLDNKTDSTGTHS
Site 91S663QLDNKTDSTGTHSLY
Site 92T664LDNKTDSTGTHSLYT
Site 93S668TDSTGTHSLYTTYKD
Site 94Y670STGTHSLYTTYKDYE
Site 95T672GTHSLYTTYKDYELM
Site 96Y676LYTTYKDYELMFHVS
Site 97T720EPGALPFTPKSIRSH
Site 98S723ALPFTPKSIRSHFQH
Site 99Y747PCTENVCYSVGVSRS
Site 100S748CTENVCYSVGVSRSK
Site 101S752VCYSVGVSRSKDVPP
Site 102S754YSVGVSRSKDVPPFG
Site 103S794AENAAHKSEKFRAMA
Site 104Y808ATRTRQEYLKDLAEN
Site 105T818DLAENFVTTATVDTS
Site 106S829VDTSVKFSFITLGAK
Site 107T948IVTRGCETVEMTLRR
Site 108T952GCETVEMTLRRNGLG
Site 109S989KAGLRQGSRLVEICK
Site 110T1003KVAVATLTHEQMIDL
Site 111S1029IQPHDDGSPRRGCSE
Site 112S1035GSPRRGCSELCRIPM
Site 113S1049MVEYKLDSEGTPCEY
Site 114T1052YKLDSEGTPCEYKTP
Site 115Y1056SEGTPCEYKTPFRRN
Site 116T1058GTPCEYKTPFRRNTT
Site 117T1064KTPFRRNTTWHRVPT
Site 118T1065TPFRRNTTWHRVPTP
Site 119T1071TTWHRVPTPALQPLS
Site 120S1078TPALQPLSRASPIPG
Site 121S1081LQPLSRASPIPGTPD
Site 122T1086RASPIPGTPDRLPCQ
Site 123S1106AQAAIPRSTSFDRKL
Site 124T1107QAAIPRSTSFDRKLP
Site 125S1108AAIPRSTSFDRKLPD
Site 126T1117DRKLPDGTRSSPSNQ
Site 127S1119KLPDGTRSSPSNQSS
Site 128S1120LPDGTRSSPSNQSSS
Site 129S1122DGTRSSPSNQSSSSD
Site 130S1125RSSPSNQSSSSDPGP
Site 131S1126SSPSNQSSSSDPGPG
Site 132S1127SPSNQSSSSDPGPGG
Site 133S1128PSNQSSSSDPGPGGS
Site 134S1135SDPGPGGSGPWRPQV
Site 135Y1144PWRPQVGYDGCQSPL
Site 136S1149VGYDGCQSPLLLEHQ
Site 137S1158LLLEHQGSGPLECDG
Site 138T1172GAREREDTMEASRHP
Site 139T1181EASRHPETKWHGPPS
Site 140S1188TKWHGPPSKVLGSYK
Site 141Y1194PSKVLGSYKERALQK
Site 142S1204RALQKDGSCKDSPNK
Site 143S1208KDGSCKDSPNKLSHI
Site 144S1213KDSPNKLSHIGDKSC
Site 145S1219LSHIGDKSCSSHSSS
Site 146S1221HIGDKSCSSHSSSNT
Site 147S1222IGDKSCSSHSSSNTL
Site 148S1224DKSCSSHSSSNTLSS
Site 149S1225KSCSSHSSSNTLSSN
Site 150S1226SCSSHSSSNTLSSNT
Site 151T1228SSHSSSNTLSSNTSS
Site 152S1230HSSSNTLSSNTSSNS
Site 153S1231SSSNTLSSNTSSNSD
Site 154S1234NTLSSNTSSNSDDKH
Site 155S1235TLSSNTSSNSDDKHF
Site 156S1237SSNTSSNSDDKHFGS
Site 157S1244SDDKHFGSGDLMDPE
Site 158Y1257PELLGLTYIKGASTD
Site 159S1265IKGASTDSGIDTAPC
Site 160T1269STDSGIDTAPCMPAT
Site 161S1286GPVHLAGSRSLIHSR
Site 162S1288VHLAGSRSLIHSRAE
Site 163S1292GSRSLIHSRAEQWAD
Site 164S1304WADAADVSGPDDEPA
Site 165Y1314DDEPAKLYSVHGYAS
Site 166S1315DEPAKLYSVHGYAST
Site 167Y1319KLYSVHGYASTISAG
Site 168S1321YSVHGYASTISAGSA
Site 169S1324HGYASTISAGSAAEG
Site 170S1332AGSAAEGSMGDLSEI
Site 171S1337EGSMGDLSEISSHSS
Site 172S1340MGDLSEISSHSSGSH
Site 173S1341GDLSEISSHSSGSHH
Site 174S1343LSEISSHSSGSHHSG
Site 175S1344SEISSHSSGSHHSGS
Site 176S1346ISSHSSGSHHSGSPS
Site 177S1349HSSGSHHSGSPSAHC
Site 178S1351SGSHHSGSPSAHCSK
Site 179S1353SHHSGSPSAHCSKSS
Site 180S1357GSPSAHCSKSSGSLD
Site 181S1359PSAHCSKSSGSLDSS
Site 182S1360SAHCSKSSGSLDSSK
Site 183S1362HCSKSSGSLDSSKVY
Site 184S1365KSSGSLDSSKVYIVS
Site 185S1366SSGSLDSSKVYIVSH
Site 186Y1369SLDSSKVYIVSHSSG
Site 187S1372SSKVYIVSHSSGQQV
Site 188S1382SGQQVPGSMSKPYHR
Site 189S1384QQVPGSMSKPYHRQG
Site 190Y1387PGSMSKPYHRQGAVN
Site 191Y1396RQGAVNKYVIGWKKS
Site 192S1403YVIGWKKSEGSPPPE
Site 193S1406GWKKSEGSPPPEEPE
Site 194T1415PPEEPEVTECPGMYS
Site 195Y1421VTECPGMYSEMDVMS
Site 196T1435STATQHQTVVGDAVA
Site 197S1461LKLMLPDSPLVEEGR
Site 198S1472EEGRRKFSFYGNLSP
Site 199Y1474GRRKFSFYGNLSPRR
Site 200S1478FSFYGNLSPRRSLYR
Site 201S1482GNLSPRRSLYRTLSD
Site 202Y1484LSPRRSLYRTLSDES
Site 203T1486PRRSLYRTLSDESIC
Site 204S1488RSLYRTLSDESICSN
Site 205S1491YRTLSDESICSNRRG
Site 206S1494LSDESICSNRRGSSF
Site 207S1499ICSNRRGSSFGSSRS
Site 208S1500CSNRRGSSFGSSRSS
Site 209S1503RRGSSFGSSRSSVLD
Site 210S1504RGSSFGSSRSSVLDQ
Site 211S1506SSFGSSRSSVLDQAL
Site 212S1507SFGSSRSSVLDQALP
Site 213S1520LPNDILFSTTPPYHS
Site 214T1521PNDILFSTTPPYHST
Site 215T1522NDILFSTTPPYHSTL
Site 216Y1525LFSTTPPYHSTLPPR
Site 217S1527STTPPYHSTLPPRAH
Site 218T1528TTPPYHSTLPPRAHP
Site 219S1538PRAHPAPSMGSLRNE
Site 220S1541HPAPSMGSLRNEFWF
Site 221S1549LRNEFWFSDGSLSDK
Site 222S1552EFWFSDGSLSDKSKC
Site 223S1554WFSDGSLSDKSKCAD
Site 224S1557DGSLSDKSKCADPGL
Site 225T1572MPLPDTATGLDWTHL
Site 226T1577TATGLDWTHLVDAAR
Site 227S1591RAFEGLDSDEELGLL
Site 228S1603GLLCHHTSYLDQRVA
Site 229Y1604LLCHHTSYLDQRVAS
Site 230S1638PLCVDPGSGKEFMDT
Site 231T1645SGKEFMDTTGERSPS
Site 232T1646GKEFMDTTGERSPSP
Site 233S1650MDTTGERSPSPLTGK
Site 234S1652TTGERSPSPLTGKVN
Site 235T1670LILRQLQTDLRKEKQ
Site 236S1700NMRLQEESQTATAQL
Site 237T1702RLQEESQTATAQLRK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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