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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLHL9
Full Name:
Kelch-like protein 9
Alias:
Type:
Phosphoprotein
Mass (Da):
69429
Number AA:
617
UniProt ID:
Q9P2J3
International Prot ID:
IPI00002249
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
G
N
G
E
M
G
V
S
A
H
L
Q
P
C
K
Site 2
T23
L
Q
P
C
K
A
G
T
T
R
F
F
T
S
N
Site 3
T28
A
G
T
T
R
F
F
T
S
N
T
H
S
S
V
Site 4
S29
G
T
T
R
F
F
T
S
N
T
H
S
S
V
V
Site 5
T31
T
R
F
F
T
S
N
T
H
S
S
V
V
L
Q
Site 6
S34
F
T
S
N
T
H
S
S
V
V
L
Q
G
F
D
Site 7
S72
V
H
R
A
M
M
A
S
A
S
D
Y
F
K
A
Site 8
Y76
M
M
A
S
A
S
D
Y
F
K
A
M
F
T
G
Site 9
T125
N
M
D
N
L
Q
D
T
L
E
A
A
S
F
L
Site 10
Y164
V
G
R
I
A
N
T
Y
N
L
I
E
V
D
K
Site 11
S203
E
R
L
A
F
V
L
S
S
N
S
L
K
H
C
Site 12
Y232
L
E
D
P
R
M
D
Y
A
A
K
L
M
K
N
Site 13
T246
N
I
R
F
P
L
M
T
P
Q
D
L
I
N
Y
Site 14
Y253
T
P
Q
D
L
I
N
Y
V
Q
T
V
D
F
M
Site 15
T265
D
F
M
R
T
D
N
T
C
V
N
L
L
L
E
Site 16
Y276
L
L
L
E
A
S
N
Y
Q
M
M
P
Y
M
Q
Site 17
S288
Y
M
Q
P
V
M
Q
S
D
R
T
A
I
R
S
Site 18
T291
P
V
M
Q
S
D
R
T
A
I
R
S
D
S
T
Site 19
S295
S
D
R
T
A
I
R
S
D
S
T
H
L
V
T
Site 20
S297
R
T
A
I
R
S
D
S
T
H
L
V
T
L
G
Site 21
T302
S
D
S
T
H
L
V
T
L
G
G
V
L
R
Q
Site 22
Y320
V
S
K
E
L
R
M
Y
D
E
R
A
Q
E
W
Site 23
S329
E
R
A
Q
E
W
R
S
L
A
P
M
D
A
P
Site 24
Y358
V
V
G
G
Q
S
N
Y
D
T
K
G
K
T
A
Site 25
T360
G
G
Q
S
N
Y
D
T
K
G
K
T
A
V
D
Site 26
T368
K
G
K
T
A
V
D
T
V
F
R
F
D
P
R
Site 27
Y376
V
F
R
F
D
P
R
Y
N
K
W
M
Q
V
A
Site 28
T390
A
S
L
N
E
K
R
T
F
F
H
L
S
A
L
Site 29
S395
K
R
T
F
F
H
L
S
A
L
K
G
H
L
Y
Site 30
Y402
S
A
L
K
G
H
L
Y
A
V
G
G
R
S
A
Site 31
Y419
E
L
A
T
V
E
C
Y
N
P
R
M
N
E
W
Site 32
Y428
P
R
M
N
E
W
S
Y
V
A
K
M
S
E
P
Site 33
Y437
A
K
M
S
E
P
H
Y
G
H
A
G
T
V
Y
Site 34
T458
S
G
G
I
T
H
D
T
F
Q
N
E
L
M
C
Site 35
T506
G
G
N
H
F
R
G
T
S
D
Y
D
D
V
L
Site 36
S507
G
N
H
F
R
G
T
S
D
Y
D
D
V
L
S
Site 37
Y509
H
F
R
G
T
S
D
Y
D
D
V
L
S
C
E
Site 38
S514
S
D
Y
D
D
V
L
S
C
E
Y
Y
S
P
T
Site 39
Y517
D
D
V
L
S
C
E
Y
Y
S
P
T
L
D
Q
Site 40
Y518
D
V
L
S
C
E
Y
Y
S
P
T
L
D
Q
W
Site 41
S519
V
L
S
C
E
Y
Y
S
P
T
L
D
Q
W
T
Site 42
T526
S
P
T
L
D
Q
W
T
P
I
A
A
M
L
R
Site 43
Y567
M
V
E
I
V
Q
K
Y
D
P
E
K
D
E
W
Site 44
T593
G
I
R
A
C
T
L
T
V
F
P
P
E
E
N
Site 45
S603
P
P
E
E
N
P
G
S
P
S
R
E
S
P
L
Site 46
S605
E
E
N
P
G
S
P
S
R
E
S
P
L
S
A
Site 47
S608
P
G
S
P
S
R
E
S
P
L
S
A
P
S
D
Site 48
S611
P
S
R
E
S
P
L
S
A
P
S
D
H
S
_
Site 49
S614
E
S
P
L
S
A
P
S
D
H
S
_
_
_
_
Site 50
S617
L
S
A
P
S
D
H
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation