KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
RBM27
Full Name:
RNA-binding protein 27
Alias:
RNA binding motif protein 27; RNA-binding motif protein 27
Type:
RNA binding protein
Mass (Da):
118718
Number AA:
1060
UniProt ID:
Q9P2N5
International Prot ID:
IPI00292975
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016607
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
E
D
V
D
A
L
K
S
W
L
A
K
L
L
E
Site 2
S71
F
V
D
K
L
F
E
S
L
Y
T
K
N
Y
L
Site 3
Y73
D
K
L
F
E
S
L
Y
T
K
N
Y
L
P
L
Site 4
T74
K
L
F
E
S
L
Y
T
K
N
Y
L
P
L
L
Site 5
Y77
E
S
L
Y
T
K
N
Y
L
P
L
L
E
P
V
Site 6
Y118
R
D
G
R
K
K
K
Y
P
S
P
Q
K
T
R
Site 7
S120
G
R
K
K
K
Y
P
S
P
Q
K
T
R
S
E
Site 8
T124
K
Y
P
S
P
Q
K
T
R
S
E
S
S
E
R
Site 9
S126
P
S
P
Q
K
T
R
S
E
S
S
E
R
R
T
Site 10
S128
P
Q
K
T
R
S
E
S
S
E
R
R
T
R
E
Site 11
S129
Q
K
T
R
S
E
S
S
E
R
R
T
R
E
K
Site 12
T133
S
E
S
S
E
R
R
T
R
E
K
K
R
E
D
Site 13
Y146
E
D
G
K
W
R
D
Y
D
R
Y
Y
E
R
N
Site 14
Y149
K
W
R
D
Y
D
R
Y
Y
E
R
N
E
L
Y
Site 15
Y150
W
R
D
Y
D
R
Y
Y
E
R
N
E
L
Y
R
Site 16
Y156
Y
Y
E
R
N
E
L
Y
R
E
K
Y
D
W
R
Site 17
Y160
N
E
L
Y
R
E
K
Y
D
W
R
R
G
R
S
Site 18
S167
Y
D
W
R
R
G
R
S
K
S
R
S
K
S
R
Site 19
S169
W
R
R
G
R
S
K
S
R
S
K
S
R
G
L
Site 20
S171
R
G
R
S
K
S
R
S
K
S
R
G
L
S
R
Site 21
S173
R
S
K
S
R
S
K
S
R
G
L
S
R
S
R
Site 22
S177
R
S
K
S
R
G
L
S
R
S
R
S
R
S
R
Site 23
S179
K
S
R
G
L
S
R
S
R
S
R
S
R
G
R
Site 24
S181
R
G
L
S
R
S
R
S
R
S
R
G
R
S
K
Site 25
S183
L
S
R
S
R
S
R
S
R
G
R
S
K
D
R
Site 26
S187
R
S
R
S
R
G
R
S
K
D
R
D
P
N
R
Site 27
S202
N
V
E
H
R
E
R
S
K
F
K
S
E
R
N
Site 28
S206
R
E
R
S
K
F
K
S
E
R
N
D
L
E
S
Site 29
S213
S
E
R
N
D
L
E
S
S
Y
V
P
V
S
A
Site 30
S214
E
R
N
D
L
E
S
S
Y
V
P
V
S
A
P
Site 31
Y215
R
N
D
L
E
S
S
Y
V
P
V
S
A
P
P
Site 32
S219
E
S
S
Y
V
P
V
S
A
P
P
P
N
S
S
Site 33
S225
V
S
A
P
P
P
N
S
S
E
Q
Y
S
S
G
Site 34
S226
S
A
P
P
P
N
S
S
E
Q
Y
S
S
G
A
Site 35
Y229
P
P
N
S
S
E
Q
Y
S
S
G
A
Q
S
I
Site 36
S230
P
N
S
S
E
Q
Y
S
S
G
A
Q
S
I
P
Site 37
S231
N
S
S
E
Q
Y
S
S
G
A
Q
S
I
P
S
Site 38
S235
Q
Y
S
S
G
A
Q
S
I
P
S
T
V
T
V
Site 39
T253
A
H
H
S
E
N
T
T
E
S
W
S
N
Y
Y
Site 40
Y259
T
T
E
S
W
S
N
Y
Y
N
N
H
S
S
S
Site 41
Y260
T
E
S
W
S
N
Y
Y
N
N
H
S
S
S
N
Site 42
S264
S
N
Y
Y
N
N
H
S
S
S
N
S
F
G
R
Site 43
S266
Y
Y
N
N
H
S
S
S
N
S
F
G
R
N
L
Site 44
S268
N
N
H
S
S
S
N
S
F
G
R
N
L
P
P
Site 45
Y282
P
K
R
R
C
R
D
Y
D
E
R
G
F
C
V
Site 46
S360
P
G
P
G
P
G
H
S
M
R
L
P
V
P
Q
Site 47
S375
G
H
G
Q
P
P
P
S
V
V
L
P
I
P
R
Site 48
T386
P
I
P
R
P
P
I
T
Q
S
S
L
I
N
S
Site 49
S388
P
R
P
P
I
T
Q
S
S
L
I
N
S
R
D
Site 50
S389
R
P
P
I
T
Q
S
S
L
I
N
S
R
D
Q
Site 51
S393
T
Q
S
S
L
I
N
S
R
D
Q
P
G
T
S
Site 52
T399
N
S
R
D
Q
P
G
T
S
A
V
P
N
L
A
Site 53
S400
S
R
D
Q
P
G
T
S
A
V
P
N
L
A
S
Site 54
Y422
P
L
P
Q
N
L
L
Y
T
V
S
E
R
Q
P
Site 55
T423
L
P
Q
N
L
L
Y
T
V
S
E
R
Q
P
M
Site 56
S425
Q
N
L
L
Y
T
V
S
E
R
Q
P
M
Y
S
Site 57
Y431
V
S
E
R
Q
P
M
Y
S
R
E
H
G
A
A
Site 58
S432
S
E
R
Q
P
M
Y
S
R
E
H
G
A
A
A
Site 59
S440
R
E
H
G
A
A
A
S
E
R
L
Q
L
G
T
Site 60
T447
S
E
R
L
Q
L
G
T
P
P
P
L
L
A
A
Site 61
S465
P
P
R
N
L
M
G
S
S
I
G
Y
H
T
S
Site 62
Y469
L
M
G
S
S
I
G
Y
H
T
S
V
S
S
P
Site 63
T471
G
S
S
I
G
Y
H
T
S
V
S
S
P
T
P
Site 64
S472
S
S
I
G
Y
H
T
S
V
S
S
P
T
P
L
Site 65
S474
I
G
Y
H
T
S
V
S
S
P
T
P
L
V
P
Site 66
S475
G
Y
H
T
S
V
S
S
P
T
P
L
V
P
D
Site 67
T477
H
T
S
V
S
S
P
T
P
L
V
P
D
T
Y
Site 68
T483
P
T
P
L
V
P
D
T
Y
E
P
D
G
Y
N
Site 69
Y484
T
P
L
V
P
D
T
Y
E
P
D
G
Y
N
P
Site 70
Y489
D
T
Y
E
P
D
G
Y
N
P
E
A
P
S
I
Site 71
S495
G
Y
N
P
E
A
P
S
I
T
S
S
G
R
S
Site 72
S498
P
E
A
P
S
I
T
S
S
G
R
S
Q
Y
R
Site 73
S499
E
A
P
S
I
T
S
S
G
R
S
Q
Y
R
Q
Site 74
S502
S
I
T
S
S
G
R
S
Q
Y
R
Q
F
F
S
Site 75
Y504
T
S
S
G
R
S
Q
Y
R
Q
F
F
S
R
T
Site 76
T511
Y
R
Q
F
F
S
R
T
Q
T
Q
R
P
N
L
Site 77
T513
Q
F
F
S
R
T
Q
T
Q
R
P
N
L
I
G
Site 78
S523
P
N
L
I
G
L
T
S
G
D
M
D
V
N
P
Site 79
S546
T
E
P
P
V
P
V
S
I
N
S
N
I
T
R
Site 80
S560
R
V
V
L
E
P
D
S
R
K
R
A
M
S
G
Site 81
S566
D
S
R
K
R
A
M
S
G
L
E
G
P
L
T
Site 82
T573
S
G
L
E
G
P
L
T
K
K
P
W
L
G
K
Site 83
Y597
G
F
L
R
K
N
Q
Y
T
N
T
K
L
E
V
Site 84
T598
F
L
R
K
N
Q
Y
T
N
T
K
L
E
V
K
Site 85
S622
T
K
L
N
E
H
F
S
K
F
G
T
I
V
N
Site 86
Y645
P
E
A
A
L
I
Q
Y
L
T
N
E
E
A
R
Site 87
S657
E
A
R
K
A
I
S
S
T
E
A
V
L
N
N
Site 88
T658
A
R
K
A
I
S
S
T
E
A
V
L
N
N
R
Site 89
T680
R
E
N
N
E
Q
P
T
L
Q
S
S
A
Q
L
Site 90
S684
E
Q
P
T
L
Q
S
S
A
Q
L
L
L
Q
Q
Site 91
T694
L
L
L
Q
Q
Q
Q
T
L
S
H
L
S
Q
Q
Site 92
S696
L
Q
Q
Q
Q
T
L
S
H
L
S
Q
Q
H
H
Site 93
S699
Q
Q
T
L
S
H
L
S
Q
Q
H
H
H
L
P
Site 94
T723
V
A
Q
S
A
P
S
T
V
H
G
G
I
Q
K
Site 95
S733
G
G
I
Q
K
M
M
S
K
P
Q
T
S
G
A
Site 96
T737
K
M
M
S
K
P
Q
T
S
G
A
Y
V
L
N
Site 97
S738
M
M
S
K
P
Q
T
S
G
A
Y
V
L
N
K
Site 98
Y741
K
P
Q
T
S
G
A
Y
V
L
N
K
V
P
V
Site 99
S760
G
H
A
G
G
N
Q
S
D
A
S
H
L
L
N
Site 100
S763
G
G
N
Q
S
D
A
S
H
L
L
N
Q
S
G
Site 101
S769
A
S
H
L
L
N
Q
S
G
G
A
G
E
D
C
Site 102
T781
E
D
C
Q
I
F
S
T
P
G
H
P
K
M
I
Site 103
Y789
P
G
H
P
K
M
I
Y
S
S
S
N
L
K
T
Site 104
S790
G
H
P
K
M
I
Y
S
S
S
N
L
K
T
P
Site 105
S792
P
K
M
I
Y
S
S
S
N
L
K
T
P
S
K
Site 106
T796
Y
S
S
S
N
L
K
T
P
S
K
L
C
S
G
Site 107
S798
S
S
N
L
K
T
P
S
K
L
C
S
G
S
K
Site 108
S802
K
T
P
S
K
L
C
S
G
S
K
S
H
D
V
Site 109
S804
P
S
K
L
C
S
G
S
K
S
H
D
V
Q
E
Site 110
S806
K
L
C
S
G
S
K
S
H
D
V
Q
E
V
L
Site 111
T865
E
R
A
N
I
M
K
T
L
K
E
L
G
E
K
Site 112
S874
K
E
L
G
E
K
I
S
Q
L
K
D
E
L
K
Site 113
S883
L
K
D
E
L
K
T
S
S
A
V
S
T
P
S
Site 114
S884
K
D
E
L
K
T
S
S
A
V
S
T
P
S
K
Site 115
S887
L
K
T
S
S
A
V
S
T
P
S
K
V
K
T
Site 116
T888
K
T
S
S
A
V
S
T
P
S
K
V
K
T
K
Site 117
S890
S
S
A
V
S
T
P
S
K
V
K
T
K
T
E
Site 118
T894
S
T
P
S
K
V
K
T
K
T
E
A
Q
K
E
Site 119
T896
P
S
K
V
K
T
K
T
E
A
Q
K
E
L
L
Site 120
T905
A
Q
K
E
L
L
D
T
E
L
D
L
H
K
R
Site 121
S914
L
D
L
H
K
R
L
S
S
G
E
D
T
T
E
Site 122
S915
D
L
H
K
R
L
S
S
G
E
D
T
T
E
L
Site 123
T919
R
L
S
S
G
E
D
T
T
E
L
R
K
K
L
Site 124
T920
L
S
S
G
E
D
T
T
E
L
R
K
K
L
S
Site 125
S927
T
E
L
R
K
K
L
S
Q
L
Q
V
E
A
A
Site 126
T946
L
P
V
G
R
G
K
T
M
S
S
Q
G
R
G
Site 127
S948
V
G
R
G
K
T
M
S
S
Q
G
R
G
R
G
Site 128
S949
G
R
G
K
T
M
S
S
Q
G
R
G
R
G
R
Site 129
S965
R
G
G
R
G
R
G
S
L
N
H
M
V
V
D
Site 130
T979
D
H
R
P
K
A
L
T
V
G
G
F
I
E
E
Site 131
S996
E
D
L
L
Q
H
F
S
T
A
N
Q
G
P
K
Site 132
S1012
K
D
R
R
L
Q
I
S
W
H
K
P
K
V
P
Site 133
S1020
W
H
K
P
K
V
P
S
I
S
T
E
T
E
E
Site 134
T1023
P
K
V
P
S
I
S
T
E
T
E
E
E
E
V
Site 135
T1037
V
K
E
E
E
T
E
T
S
D
L
F
L
P
D
Site 136
S1038
K
E
E
E
T
E
T
S
D
L
F
L
P
D
D
Site 137
Y1053
D
D
E
D
E
D
E
Y
E
S
R
S
W
R
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation