PhosphoNET

           
Protein Info 
   
Short Name:  NRXN2
Full Name:  Neurexin-2-alpha
Alias:  Neurexin 2; Neurexin II; Neurexin II-alpha; NRX2A
Type:  Membrane, Integral membrane protein
Mass (Da):  184982
Number AA:  1712
UniProt ID:  Q9P2S2
International Prot ID:  IPI00007921
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0016021     Uniprot OncoNet
Molecular Function:  GO:0005509  GO:0005515   PhosphoSite+ KinaseNET
Biological Process:  GO:0007155     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T10SGSRWRPTPPPLLLL
Site 2Y41GPGQWARYARWAGAA
Site 3S544RAGGGAGSHSSAQRA
Site 4S546GGGAGSHSSAQRADY
Site 5S547GGAGSHSSAQRADYF
Site 6S601QRDGRKGSISVNSRS
Site 7S757HTEAEDVSLRFMSQR
Site 8S762DVSLRFMSQRAYGLM
Site 9Y766RFMSQRAYGLMMATT
Site 10T772AYGLMMATTSRESAD
Site 11S774GLMMATTSRESADTL
Site 12S777MATTSRESADTLRLE
Site 13T780TSRESADTLRLELDG
Site 14Y974VIELVKGYIHYVFDL
Site 15S992PSLMKGNSDKPVNDN
Site 16Y1040LDLKGELYIGGLSKN
Site 17S1382TTTRRGRSPTLRDST
Site 18T1384TRRGRSPTLRDSTTQ
Site 19S1528TDRTTLLSPRKPAPR
Site 20Y1658LILLYAMYKYRNRDE
Site 21Y1660LLYAMYKYRNRDEGS
Site 22S1667YRNRDEGSYQVDQSR
Site 23Y1668RNRDEGSYQVDQSRN
Site 24S1673GSYQVDQSRNYISNS
Site 25Y1676QVDQSRNYISNSAQS
Site 26S1678DQSRNYISNSAQSNG
Site 27S1680SRNYISNSAQSNGAV
Site 28S1683YISNSAQSNGAVVKE
Site 29T1698KAPAAPKTPSKAKKN
Site 30Y1710KKNKDKEYYV_____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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