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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GMPR2
Full Name:
GMP reductase 2
Alias:
Guanosine 5'-monophosphate oxidoreductase 2
Type:
Mass (Da):
37874
Number AA:
348
UniProt ID:
Q9P2T1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
V
L
L
R
P
K
R
S
T
L
K
S
R
S
E
Site 2
T23
L
L
R
P
K
R
S
T
L
K
S
R
S
E
V
Site 3
S26
P
K
R
S
T
L
K
S
R
S
E
V
D
L
T
Site 4
S28
R
S
T
L
K
S
R
S
E
V
D
L
T
R
S
Site 5
T33
S
R
S
E
V
D
L
T
R
S
F
S
F
R
N
Site 6
S35
S
E
V
D
L
T
R
S
F
S
F
R
N
S
K
Site 7
S37
V
D
L
T
R
S
F
S
F
R
N
S
K
Q
T
Site 8
S41
R
S
F
S
F
R
N
S
K
Q
T
Y
S
G
V
Site 9
T44
S
F
R
N
S
K
Q
T
Y
S
G
V
P
I
I
Site 10
S46
R
N
S
K
Q
T
Y
S
G
V
P
I
I
A
A
Site 11
S103
L
E
H
L
A
A
S
S
G
T
G
S
S
D
F
Site 12
S107
A
A
S
S
G
T
G
S
S
D
F
E
Q
L
E
Site 13
S108
A
S
S
G
T
G
S
S
D
F
E
Q
L
E
Q
Site 14
T153
R
K
R
F
P
Q
H
T
I
M
A
G
N
V
V
Site 15
S184
K
V
G
I
G
P
G
S
V
C
T
T
R
K
K
Site 16
T187
I
G
P
G
S
V
C
T
T
R
K
K
T
G
V
Site 17
T188
G
P
G
S
V
C
T
T
R
K
K
T
G
V
G
Site 18
T192
V
C
T
T
R
K
K
T
G
V
G
Y
P
Q
L
Site 19
Y196
R
K
K
T
G
V
G
Y
P
Q
L
S
A
V
M
Site 20
S249
G
G
M
L
A
G
H
S
E
S
G
G
E
L
I
Site 21
Y263
I
E
R
D
G
K
K
Y
K
L
F
Y
G
M
S
Site 22
Y267
G
K
K
Y
K
L
F
Y
G
M
S
S
E
M
A
Site 23
Y278
S
E
M
A
M
K
K
Y
A
G
G
V
A
E
Y
Site 24
Y285
Y
A
G
G
V
A
E
Y
R
A
S
E
G
K
T
Site 25
S288
G
V
A
E
Y
R
A
S
E
G
K
T
V
E
V
Site 26
T292
Y
R
A
S
E
G
K
T
V
E
V
P
F
K
G
Site 27
T304
F
K
G
D
V
E
H
T
I
R
D
I
L
G
G
Site 28
Y318
G
I
R
S
T
C
T
Y
V
G
A
A
K
L
K
Site 29
S328
A
A
K
L
K
E
L
S
R
R
T
T
F
I
R
Site 30
T331
L
K
E
L
S
R
R
T
T
F
I
R
V
T
Q
Site 31
T332
K
E
L
S
R
R
T
T
F
I
R
V
T
Q
Q
Site 32
T337
R
T
T
F
I
R
V
T
Q
Q
V
N
P
I
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation