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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRIT1
Full Name:
Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1
Alias:
DKFZP434K091; Fibronectin type III, immunoglobulin and leucine rich repeat domains 9; FIGLER9; Leucine-rich repeat, immunoglobulin-like and transmembrane domains 1; Leucine-rich repeat-containing protein 21; LRRC21; PAL; Photoreceptor-associated LRR superfamily protein; Retina-specific protein PAL
Type:
Mass (Da):
68041
Number AA:
623
UniProt ID:
Q9P2V4
International Prot ID:
IPI00024059
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030176
GO:0005789
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
Q
A
R
G
F
C
P
S
Q
C
S
C
S
L
H
Site 2
T42
G
D
G
S
K
A
R
T
V
V
C
N
D
P
D
Site 3
T51
V
C
N
D
P
D
M
T
L
P
P
A
S
I
P
Site 4
S56
D
M
T
L
P
P
A
S
I
P
P
D
T
S
R
Site 5
T61
P
A
S
I
P
P
D
T
S
R
L
R
L
E
R
Site 6
S62
A
S
I
P
P
D
T
S
R
L
R
L
E
R
T
Site 7
T69
S
R
L
R
L
E
R
T
A
I
R
R
V
P
G
Site 8
Y92
L
E
Q
L
W
L
P
Y
N
A
L
S
E
L
N
Site 9
S144
D
L
Q
A
N
R
L
S
A
V
P
A
E
A
A
Site 10
T158
A
R
F
L
E
N
L
T
F
L
D
L
S
S
N
Site 11
S234
E
T
E
L
R
C
A
S
P
R
S
L
A
G
V
Site 12
S286
G
V
P
G
P
E
M
S
W
R
R
A
N
G
R
Site 13
T298
N
G
R
P
L
N
G
T
V
H
Q
E
V
S
S
Site 14
S304
G
T
V
H
Q
E
V
S
S
D
G
T
S
W
T
Site 15
T308
Q
E
V
S
S
D
G
T
S
W
T
L
L
G
L
Site 16
S309
E
V
S
S
D
G
T
S
W
T
L
L
G
L
P
Site 17
S323
P
A
V
S
H
L
D
S
G
D
Y
I
C
Q
A
Site 18
Y326
S
H
L
D
S
G
D
Y
I
C
Q
A
K
N
F
Site 19
S351
I
V
T
E
P
P
T
S
T
E
H
S
G
S
P
Site 20
S355
P
P
T
S
T
E
H
S
G
S
P
G
A
L
W
Site 21
S357
T
S
T
E
H
S
G
S
P
G
A
L
W
A
R
Site 22
Y374
G
G
G
E
A
A
A
Y
N
N
K
L
V
A
R
Site 23
T394
P
K
P
A
V
L
A
T
G
P
S
V
P
S
T
Site 24
S397
A
V
L
A
T
G
P
S
V
P
S
T
K
E
E
Site 25
T401
T
G
P
S
V
P
S
T
K
E
E
L
T
L
E
Site 26
T406
P
S
T
K
E
E
L
T
L
E
H
F
Q
M
D
Site 27
S419
M
D
A
L
G
E
L
S
D
G
R
A
G
P
S
Site 28
S426
S
D
G
R
A
G
P
S
E
A
R
M
V
R
S
Site 29
S445
G
D
T
Y
H
S
V
S
L
V
W
K
A
P
Q
Site 30
T456
K
A
P
Q
A
K
N
T
T
A
F
S
V
L
Y
Site 31
T484
Q
P
G
K
T
R
V
T
I
T
G
L
L
P
K
Site 32
T486
G
K
T
R
V
T
I
T
G
L
L
P
K
T
K
Site 33
S564
R
K
C
F
N
K
D
S
T
E
A
T
V
T
Y
Site 34
T565
K
C
F
N
K
D
S
T
E
A
T
V
T
Y
V
Site 35
T568
N
K
D
S
T
E
A
T
V
T
Y
V
N
L
E
Site 36
T570
D
S
T
E
A
T
V
T
Y
V
N
L
E
R
L
Site 37
Y571
S
T
E
A
T
V
T
Y
V
N
L
E
R
L
G
Site 38
Y579
V
N
L
E
R
L
G
Y
S
E
D
G
L
E
E
Site 39
S588
E
D
G
L
E
E
L
S
R
H
S
V
S
E
A
Site 40
S591
L
E
E
L
S
R
H
S
V
S
E
A
D
R
L
Site 41
S593
E
L
S
R
H
S
V
S
E
A
D
R
L
L
S
Site 42
S600
S
E
A
D
R
L
L
S
A
R
S
S
V
D
F
Site 43
S603
D
R
L
L
S
A
R
S
S
V
D
F
Q
A
F
Site 44
S604
R
L
L
S
A
R
S
S
V
D
F
Q
A
F
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation