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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PSMC3IP
Full Name:
Homologous-pairing protein 2 homolog
Alias:
GT198; Homologous-pairing protein 2 homolog; HOP2; Nuclear receptor coactivator GT198; PSMC3 interacting protein; Tat-binding protein 1-interacting protein; TBPIP
Type:
Nuclear receptor co-regulator
Mass (Da):
24906
Number AA:
217
UniProt ID:
Q9P2W1
International Prot ID:
IPI00743396
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006310
GO:0007126
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
K
G
R
A
E
A
A
Site 2
Y27
L
Q
E
Q
N
R
P
Y
S
S
Q
D
V
F
G
Site 3
S28
Q
E
Q
N
R
P
Y
S
S
Q
D
V
F
G
N
Site 4
S29
E
Q
N
R
P
Y
S
S
Q
D
V
F
G
N
L
Site 5
Y65
G
K
I
K
E
K
M
Y
G
K
Q
K
I
Y
F
Site 6
Y71
M
Y
G
K
Q
K
I
Y
F
A
D
Q
D
Q
F
Site 7
S82
Q
D
Q
F
D
M
V
S
D
A
D
L
Q
V
L
Site 8
S102
A
L
T
A
K
V
Q
S
L
Q
Q
S
C
R
Y
Site 9
S106
K
V
Q
S
L
Q
Q
S
C
R
Y
M
E
A
E
Site 10
Y109
S
L
Q
Q
S
C
R
Y
M
E
A
E
L
K
E
Site 11
S118
E
A
E
L
K
E
L
S
S
A
L
T
T
P
E
Site 12
S119
A
E
L
K
E
L
S
S
A
L
T
T
P
E
M
Site 13
T122
K
E
L
S
S
A
L
T
T
P
E
M
Q
K
E
Site 14
T123
E
L
S
S
A
L
T
T
P
E
M
Q
K
E
I
Site 15
Y140
L
K
K
E
C
A
G
Y
R
E
R
L
K
N
I
Site 16
T155
K
A
A
T
N
H
V
T
P
E
E
K
E
Q
V
Site 17
Y163
P
E
E
K
E
Q
V
Y
R
E
R
Q
K
Y
C
Site 18
Y169
V
Y
R
E
R
Q
K
Y
C
K
E
W
R
K
R
Site 19
T181
R
K
R
K
R
M
A
T
E
L
S
D
A
I
L
Site 20
S184
K
R
M
A
T
E
L
S
D
A
I
L
E
G
Y
Site 21
Y191
S
D
A
I
L
E
G
Y
P
K
S
K
K
Q
F
Site 22
S194
I
L
E
G
Y
P
K
S
K
K
Q
F
F
E
E
Site 23
Y210
G
I
E
T
D
E
D
Y
N
V
T
L
P
D
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation