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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UVRAG
Full Name:
UV radiation resistance-associated gene protein
Alias:
P63; UV radiation resistance associated gene
Type:
Autophagy; Tumor suppressor
Mass (Da):
78151
Number AA:
699
UniProt ID:
Q9P2Y5
International Prot ID:
IPI00002614
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
Phosida
TranscriptoNet
STRING
Kinexus Products
UV radiation resistance-associated gene protein pan-specific antibody AB-NN356-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN356-1#UV radiation resistance-associated gene protein pan-specific antibody AB-NN356-2#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN356-2
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
A
L
H
V
E
L
P
S
Q
Q
R
R
L
R
H
Site 2
T64
N
G
H
Q
L
L
D
T
Y
F
T
L
H
L
C
Site 3
S83
I
Y
K
E
F
Y
R
S
E
V
I
K
N
S
L
Site 4
S89
R
S
E
V
I
K
N
S
L
N
P
T
W
R
S
Site 5
T93
I
K
N
S
L
N
P
T
W
R
S
L
D
F
G
Site 6
S96
S
L
N
P
T
W
R
S
L
D
F
G
I
M
P
Site 7
T108
I
M
P
D
R
L
D
T
S
V
S
C
F
V
V
Site 8
Y125
W
G
G
K
E
N
I
Y
Q
L
L
I
E
W
K
Site 9
Y161
I
F
G
L
N
D
G
Y
Y
G
A
P
F
E
H
Site 10
Y162
F
G
L
N
D
G
Y
Y
G
A
P
F
E
H
K
Site 11
Y171
A
P
F
E
H
K
G
Y
S
N
A
Q
K
T
I
Site 12
S172
P
F
E
H
K
G
Y
S
N
A
Q
K
T
I
L
Site 13
S190
D
Q
N
C
V
R
N
S
Y
D
V
F
S
L
L
Site 14
Y191
Q
N
C
V
R
N
S
Y
D
V
F
S
L
L
R
Site 15
S195
R
N
S
Y
D
V
F
S
L
L
R
L
H
R
A
Site 16
T212
A
I
K
Q
T
Q
V
T
V
Q
K
I
G
K
E
Site 17
T227
I
E
E
K
L
R
L
T
S
T
S
N
E
L
K
Site 18
S228
E
E
K
L
R
L
T
S
T
S
N
E
L
K
K
Site 19
S230
K
L
R
L
T
S
T
S
N
E
L
K
K
K
S
Site 20
S237
S
N
E
L
K
K
K
S
E
C
L
Q
L
K
I
Site 21
S277
I
A
L
Q
D
K
G
S
A
F
S
A
E
H
L
Site 22
T301
N
E
L
R
K
E
C
T
A
K
R
E
L
F
L
Site 23
T310
K
R
E
L
F
L
K
T
N
A
Q
L
T
I
R
Site 24
T315
L
K
T
N
A
Q
L
T
I
R
C
R
Q
L
L
Site 25
S323
I
R
C
R
Q
L
L
S
E
L
S
Y
I
Y
P
Site 26
Y329
L
S
E
L
S
Y
I
Y
P
I
D
L
N
E
H
Site 27
Y339
D
L
N
E
H
K
D
Y
F
V
C
G
V
K
L
Site 28
S349
C
G
V
K
L
P
N
S
E
D
F
Q
A
K
D
Site 29
S393
I
I
H
K
G
S
R
S
T
I
K
D
N
I
N
Site 30
T394
I
H
K
G
S
R
S
T
I
K
D
N
I
N
D
Site 31
T404
D
N
I
N
D
K
L
T
E
K
E
R
E
F
P
Site 32
Y413
K
E
R
E
F
P
L
Y
P
K
G
G
E
K
L
Site 33
Y424
G
E
K
L
Q
F
D
Y
G
V
Y
L
L
N
K
Site 34
Y438
K
N
I
A
Q
L
R
Y
Q
H
G
L
G
T
P
Site 35
T444
R
Y
Q
H
G
L
G
T
P
D
L
R
Q
T
L
Site 36
T450
G
T
P
D
L
R
Q
T
L
P
N
L
K
N
F
Site 37
T471
V
R
C
D
R
H
H
T
S
S
A
I
P
V
P
Site 38
S472
R
C
D
R
H
H
T
S
S
A
I
P
V
P
K
Site 39
S473
C
D
R
H
H
T
S
S
A
I
P
V
P
K
R
Site 40
S482
I
P
V
P
K
R
Q
S
S
I
F
G
G
A
D
Site 41
S483
P
V
P
K
R
Q
S
S
I
F
G
G
A
D
V
Site 42
S493
G
G
A
D
V
G
F
S
G
G
I
P
S
P
D
Site 43
S498
G
F
S
G
G
I
P
S
P
D
K
G
H
R
K
Site 44
S508
K
G
H
R
K
R
A
S
S
E
N
E
R
L
Q
Site 45
S509
G
H
R
K
R
A
S
S
E
N
E
R
L
Q
Y
Site 46
Y516
S
E
N
E
R
L
Q
Y
K
T
P
P
P
S
Y
Site 47
T518
N
E
R
L
Q
Y
K
T
P
P
P
S
Y
N
S
Site 48
S522
Q
Y
K
T
P
P
P
S
Y
N
S
A
L
A
Q
Site 49
T533
A
L
A
Q
P
V
T
T
V
P
S
M
G
E
T
Site 50
T540
T
V
P
S
M
G
E
T
E
R
K
I
T
S
L
Site 51
T545
G
E
T
E
R
K
I
T
S
L
S
S
S
L
D
Site 52
S546
E
T
E
R
K
I
T
S
L
S
S
S
L
D
T
Site 53
S548
E
R
K
I
T
S
L
S
S
S
L
D
T
S
L
Site 54
S549
R
K
I
T
S
L
S
S
S
L
D
T
S
L
D
Site 55
S550
K
I
T
S
L
S
S
S
L
D
T
S
L
D
F
Site 56
T553
S
L
S
S
S
L
D
T
S
L
D
F
S
K
E
Site 57
S554
L
S
S
S
L
D
T
S
L
D
F
S
K
E
N
Site 58
S558
L
D
T
S
L
D
F
S
K
E
N
K
K
K
G
Site 59
S571
K
G
E
D
L
V
G
S
L
N
G
G
H
A
N
Site 60
S582
G
H
A
N
V
H
P
S
Q
E
Q
G
E
A
L
Site 61
S590
Q
E
Q
G
E
A
L
S
G
H
R
A
T
V
N
Site 62
T599
H
R
A
T
V
N
G
T
L
L
P
S
E
Q
A
Site 63
S603
V
N
G
T
L
L
P
S
E
Q
A
G
S
A
S
Site 64
S608
L
P
S
E
Q
A
G
S
A
S
V
Q
L
P
G
Site 65
S610
S
E
Q
A
G
S
A
S
V
Q
L
P
G
E
F
Site 66
S621
P
G
E
F
H
P
V
S
E
A
E
L
C
C
T
Site 67
T628
S
E
A
E
L
C
C
T
V
E
Q
A
E
E
I
Site 68
S677
L
G
E
F
E
E
F
S
R
R
I
Y
A
L
N
Site 69
Y681
E
E
F
S
R
R
I
Y
A
L
N
E
N
V
S
Site 70
S688
Y
A
L
N
E
N
V
S
S
F
R
R
P
R
R
Site 71
S689
A
L
N
E
N
V
S
S
F
R
R
P
R
R
S
Site 72
S696
S
F
R
R
P
R
R
S
S
D
K
_
_
_
_
Site 73
S697
F
R
R
P
R
R
S
S
D
K
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation