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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HSFX1
Full Name:
Alias:
Type:
Mass (Da):
46742
Number AA:
423
UniProt ID:
Q9UBD0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
E
D
K
R
S
L
S
M
A
R
C
E
E
R
Site 2
S17
A
R
C
E
E
R
N
S
R
G
Q
D
H
G
L
Site 3
S35
P
F
P
P
Q
L
Q
S
E
T
Y
L
H
P
A
Site 4
Y38
P
Q
L
Q
S
E
T
Y
L
H
P
A
D
P
S
Site 5
S45
Y
L
H
P
A
D
P
S
P
A
W
D
D
P
G
Site 6
S53
P
A
W
D
D
P
G
S
T
G
S
P
N
L
R
Site 7
T54
A
W
D
D
P
G
S
T
G
S
P
N
L
R
L
Site 8
S56
D
D
P
G
S
T
G
S
P
N
L
R
L
L
T
Site 9
T63
S
P
N
L
R
L
L
T
E
E
I
A
F
Q
P
Site 10
S76
Q
P
L
A
E
E
A
S
F
R
R
P
H
P
D
Site 11
S96
Q
G
E
D
N
L
L
S
L
P
F
P
Q
K
L
Site 12
S108
Q
K
L
W
R
L
V
S
S
N
Q
F
S
S
I
Site 13
S109
K
L
W
R
L
V
S
S
N
Q
F
S
S
I
W
Site 14
S113
L
V
S
S
N
Q
F
S
S
I
W
W
D
D
S
Site 15
Y160
F
F
R
Q
L
N
L
Y
G
F
R
K
R
R
Q
Site 16
T169
F
R
K
R
R
Q
C
T
F
R
T
F
T
R
I
Site 17
T172
R
R
Q
C
T
F
R
T
F
T
R
I
F
S
A
Site 18
T174
Q
C
T
F
R
T
F
T
R
I
F
S
A
K
R
Site 19
Y192
I
L
N
K
L
E
F
Y
C
H
P
Y
F
Q
R
Site 20
Y196
L
E
F
Y
C
H
P
Y
F
Q
R
D
S
P
H
Site 21
S201
H
P
Y
F
Q
R
D
S
P
H
L
L
V
R
M
Site 22
S216
K
R
R
V
G
V
K
S
A
P
R
H
Q
E
E
Site 23
S231
D
K
P
E
A
A
G
S
C
L
A
P
A
D
T
Site 24
S245
T
E
Q
Q
D
H
T
S
P
N
E
N
D
Q
V
Site 25
T253
P
N
E
N
D
Q
V
T
P
Q
H
R
E
P
A
Site 26
T264
R
E
P
A
G
P
N
T
Q
I
R
S
G
S
A
Site 27
S268
G
P
N
T
Q
I
R
S
G
S
A
P
P
A
T
Site 28
S270
N
T
Q
I
R
S
G
S
A
P
P
A
T
P
V
Site 29
T275
S
G
S
A
P
P
A
T
P
V
M
V
P
D
S
Site 30
S282
T
P
V
M
V
P
D
S
A
V
A
S
D
N
S
Site 31
S286
V
P
D
S
A
V
A
S
D
N
S
P
V
T
Q
Site 32
S289
S
A
V
A
S
D
N
S
P
V
T
Q
P
A
G
Site 33
T292
A
S
D
N
S
P
V
T
Q
P
A
G
E
W
S
Site 34
S302
A
G
E
W
S
E
G
S
Q
A
H
V
T
P
V
Site 35
S326
P
F
L
Y
V
P
G
S
P
T
Q
M
N
S
Y
Site 36
T328
L
Y
V
P
G
S
P
T
Q
M
N
S
Y
G
P
Site 37
S332
G
S
P
T
Q
M
N
S
Y
G
P
V
V
A
L
Site 38
T346
L
P
T
A
S
R
S
T
L
A
M
D
T
T
G
Site 39
S403
C
P
H
S
H
R
T
S
Q
Y
M
P
A
S
D
Site 40
Y405
H
S
H
R
T
S
Q
Y
M
P
A
S
D
G
P
Site 41
S409
T
S
Q
Y
M
P
A
S
D
G
P
Q
A
Y
P
Site 42
Y415
A
S
D
G
P
Q
A
Y
P
D
Y
A
D
Q
S
Site 43
Y418
G
P
Q
A
Y
P
D
Y
A
D
Q
S
T
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation