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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ORC3L
Full Name:
Origin recognition complex subunit 3
Alias:
Homolog of latheo, Drosophila; IMAGE50150; LAT; LATHEO; ORC3; Origin recognition complex subunit Latheo; Origin recognition complex, subunit 3; Origin recognition complex, subunit 3 (yeast homolog)-like; Origin recognition complex, subunit 3-like; Origin recognition complex, subunit 3-like (yeast)
Type:
Cell cycle regulation
Mass (Da):
82254
Number AA:
711
UniProt ID:
Q9UBD5
International Prot ID:
IPI00294402
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005664
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0003688
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
C
F
V
F
K
P
N
S
K
K
R
K
I
S
L
Site 2
S23
N
S
K
K
R
K
I
S
L
P
I
E
D
Y
F
Site 3
Y29
I
S
L
P
I
E
D
Y
F
N
K
G
K
N
E
Site 4
S40
G
K
N
E
P
E
D
S
K
L
R
F
E
T
Y
Site 5
T46
D
S
K
L
R
F
E
T
Y
Q
L
I
W
Q
Q
Site 6
Y47
S
K
L
R
F
E
T
Y
Q
L
I
W
Q
Q
M
Site 7
S56
L
I
W
Q
Q
M
K
S
E
N
E
R
L
Q
E
Site 8
S80
L
I
E
F
L
Q
K
S
H
S
G
F
Q
K
N
Site 9
S82
E
F
L
Q
K
S
H
S
G
F
Q
K
N
S
R
Site 10
S88
H
S
G
F
Q
K
N
S
R
D
L
G
G
Q
I
Site 11
T117
N
V
T
D
H
D
L
T
F
G
S
L
T
E
A
Site 12
S120
D
H
D
L
T
F
G
S
L
T
E
A
L
Q
N
Site 13
T130
E
A
L
Q
N
N
V
T
P
Y
V
V
S
L
Q
Site 14
Y132
L
Q
N
N
V
T
P
Y
V
V
S
L
Q
A
K
Site 15
S164
D
C
C
V
D
I
K
S
K
E
E
E
S
V
H
Site 16
S169
I
K
S
K
E
E
E
S
V
H
V
T
Q
R
K
Site 17
T173
E
E
E
S
V
H
V
T
Q
R
K
T
H
Y
S
Site 18
T177
V
H
V
T
Q
R
K
T
H
Y
S
M
D
S
L
Site 19
Y179
V
T
Q
R
K
T
H
Y
S
M
D
S
L
S
S
Site 20
S180
T
Q
R
K
T
H
Y
S
M
D
S
L
S
S
W
Site 21
T190
S
L
S
S
W
Y
M
T
V
T
Q
K
T
D
P
Site 22
T192
S
S
W
Y
M
T
V
T
Q
K
T
D
P
K
M
Site 23
S201
K
T
D
P
K
M
L
S
K
K
R
T
T
S
S
Site 24
T205
K
M
L
S
K
K
R
T
T
S
S
Q
W
Q
S
Site 25
T206
M
L
S
K
K
R
T
T
S
S
Q
W
Q
S
P
Site 26
S207
L
S
K
K
R
T
T
S
S
Q
W
Q
S
P
P
Site 27
S208
S
K
K
R
T
T
S
S
Q
W
Q
S
P
P
V
Site 28
T227
K
D
M
E
S
F
A
T
K
V
L
Q
D
F
I
Site 29
S280
I
E
L
F
Q
S
L
S
C
K
E
H
L
T
T
Site 30
S371
E
N
I
R
R
L
P
S
F
R
R
Y
V
E
K
Site 31
Y375
R
L
P
S
F
R
R
Y
V
E
K
Q
A
S
E
Site 32
S381
R
Y
V
E
K
Q
A
S
E
K
Q
V
A
L
L
Site 33
T389
E
K
Q
V
A
L
L
T
N
E
R
Y
L
K
E
Site 34
Y393
A
L
L
T
N
E
R
Y
L
K
E
E
T
Q
L
Site 35
S424
R
C
L
H
K
F
T
S
S
L
P
K
Y
P
L
Site 36
S425
C
L
H
K
F
T
S
S
L
P
K
Y
P
L
G
Site 37
Y429
F
T
S
S
L
P
K
Y
P
L
G
R
Q
I
R
Site 38
Y439
G
R
Q
I
R
E
L
Y
C
T
C
L
E
K
N
Site 39
S455
W
D
S
E
E
Y
A
S
V
L
Q
L
L
R
M
Site 40
S503
E
F
L
A
Q
F
Q
S
L
D
E
T
K
E
E
Site 41
T507
Q
F
Q
S
L
D
E
T
K
E
E
E
D
A
S
Site 42
S514
T
K
E
E
E
D
A
S
G
S
Q
P
K
G
L
Site 43
S516
E
E
E
D
A
S
G
S
Q
P
K
G
L
Q
K
Site 44
T524
Q
P
K
G
L
Q
K
T
D
L
Y
H
L
Q
K
Site 45
Y527
G
L
Q
K
T
D
L
Y
H
L
Q
K
S
L
L
Site 46
S532
D
L
Y
H
L
Q
K
S
L
L
E
M
K
E
L
Site 47
S542
E
M
K
E
L
R
R
S
K
K
Q
T
K
F
E
Site 48
T546
L
R
R
S
K
K
Q
T
K
F
E
V
L
R
E
Site 49
Y566
I
D
C
L
V
R
E
Y
L
L
P
P
E
T
Q
Site 50
T572
E
Y
L
L
P
P
E
T
Q
P
L
H
E
V
V
Site 51
T601
A
P
R
I
A
L
H
T
A
L
N
N
P
Y
Y
Site 52
Y607
H
T
A
L
N
N
P
Y
Y
Y
L
K
N
E
A
Site 53
Y608
T
A
L
N
N
P
Y
Y
Y
L
K
N
E
A
L
Site 54
Y609
T
A
L
N
N
P
Y
Y
Y
L
K
N
E
A
L
Site 55
S617
L
K
N
E
A
L
K
S
E
E
G
C
I
P
N
Site 56
T654
D
W
S
E
A
F
A
T
V
V
T
A
A
E
K
Site 57
S666
A
E
K
M
D
A
N
S
A
T
S
E
E
M
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation