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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
UBLE1A
Full Name:
SUMO-activating enzyme subunit 1
Alias:
activator of sumo 1; AOS1; FLJ3091; HSPC140; SAE1; SUA1; SUMO-1 activating enzyme E1 N subunit; SUMO1 activating enzyme subunit 1; ULE1A
Type:
Ubiquitin conjugating system
Mass (Da):
38450
Number AA:
346
UniProt ID:
Q9UBE0
International Prot ID:
IPI00033130
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043008
GO:0008047
GO:0016874
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
GO:0016567
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
E
E
A
G
G
G
I
S
E
E
E
A
A
Q
Y
Site 2
Y19
S
E
E
E
A
A
Q
Y
D
R
Q
I
R
L
W
Site 3
S37
A
Q
K
R
L
R
A
S
R
V
L
L
V
G
L
Site 4
T72
M
L
D
H
E
Q
V
T
P
E
D
P
G
A
Q
Site 5
S86
Q
F
L
I
R
T
G
S
V
G
R
N
R
A
E
Site 6
S95
G
R
N
R
A
E
A
S
L
E
R
A
Q
N
L
Site 7
S121
D
I
E
K
K
P
E
S
F
F
T
Q
F
D
A
Site 8
T124
K
K
P
E
S
F
F
T
Q
F
D
A
V
C
L
Site 9
S185
K
T
K
V
A
K
V
S
Q
G
V
E
D
G
P
Site 10
T194
G
V
E
D
G
P
D
T
K
R
A
K
L
D
S
Site 11
S201
T
K
R
A
K
L
D
S
S
E
T
T
M
V
K
Site 12
S202
K
R
A
K
L
D
S
S
E
T
T
M
V
K
K
Site 13
T205
K
L
D
S
S
E
T
T
M
V
K
K
K
V
V
Site 14
S225
E
A
L
E
V
D
W
S
S
E
K
A
K
A
A
Site 15
S226
A
L
E
V
D
W
S
S
E
K
A
K
A
A
L
Site 16
T237
K
A
A
L
K
R
T
T
S
D
Y
F
L
L
Q
Site 17
S258
T
D
K
G
R
D
P
S
S
D
T
Y
E
E
D
Site 18
S259
D
K
G
R
D
P
S
S
D
T
Y
E
E
D
S
Site 19
T261
G
R
D
P
S
S
D
T
Y
E
E
D
S
E
L
Site 20
Y262
R
D
P
S
S
D
T
Y
E
E
D
S
E
L
L
Site 21
S319
Q
E
I
V
K
A
L
S
Q
R
D
P
P
H
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation