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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CRNN
Full Name:
Cornulin
Alias:
C1orf10; PDRC1; SEP53
Type:
Mass (Da):
53533
Number AA:
495
UniProt ID:
Q9UBG3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0016337
GO:0009408
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
I
I
E
A
F
R
R
Y
A
R
T
E
G
N
C
Site 2
T21
A
F
R
R
Y
A
R
T
E
G
N
C
T
A
L
Site 3
T26
A
R
T
E
G
N
C
T
A
L
T
R
G
E
L
Site 4
T53
V
K
P
H
D
P
A
T
V
D
E
V
L
R
L
Site 5
T66
R
L
L
D
E
D
H
T
G
T
V
E
F
K
E
Site 6
T68
L
D
E
D
H
T
G
T
V
E
F
K
E
F
L
Site 7
T88
V
A
Q
A
C
F
K
T
L
S
E
S
A
E
G
Site 8
S90
Q
A
C
F
K
T
L
S
E
S
A
E
G
A
C
Site 9
S92
C
F
K
T
L
S
E
S
A
E
G
A
C
G
S
Site 10
S99
S
A
E
G
A
C
G
S
Q
E
S
G
S
L
H
Site 11
S102
G
A
C
G
S
Q
E
S
G
S
L
H
S
G
A
Site 12
S104
C
G
S
Q
E
S
G
S
L
H
S
G
A
S
Q
Site 13
S110
G
S
L
H
S
G
A
S
Q
E
L
G
E
G
Q
Site 14
S119
E
L
G
E
G
Q
R
S
G
T
E
V
G
R
A
Site 15
T121
G
E
G
Q
R
S
G
T
E
V
G
R
A
G
K
Site 16
Y132
R
A
G
K
G
Q
H
Y
E
G
S
S
H
R
Q
Site 17
S135
K
G
Q
H
Y
E
G
S
S
H
R
Q
S
Q
Q
Site 18
S136
G
Q
H
Y
E
G
S
S
H
R
Q
S
Q
Q
G
Site 19
S140
E
G
S
S
H
R
Q
S
Q
Q
G
S
R
G
Q
Site 20
S144
H
R
Q
S
Q
Q
G
S
R
G
Q
N
R
P
G
Site 21
T154
Q
N
R
P
G
V
Q
T
Q
G
Q
A
T
G
S
Site 22
S161
T
Q
G
Q
A
T
G
S
A
W
V
S
S
Y
D
Site 23
S165
A
T
G
S
A
W
V
S
S
Y
D
R
Q
A
E
Site 24
S166
T
G
S
A
W
V
S
S
Y
D
R
Q
A
E
S
Site 25
Y167
G
S
A
W
V
S
S
Y
D
R
Q
A
E
S
Q
Site 26
S173
S
Y
D
R
Q
A
E
S
Q
S
Q
E
R
I
S
Site 27
S175
D
R
Q
A
E
S
Q
S
Q
E
R
I
S
P
Q
Site 28
S180
S
Q
S
Q
E
R
I
S
P
Q
I
Q
L
S
G
Site 29
S186
I
S
P
Q
I
Q
L
S
G
Q
T
E
Q
T
Q
Site 30
T189
Q
I
Q
L
S
G
Q
T
E
Q
T
Q
K
A
G
Site 31
T203
G
E
G
K
R
N
Q
T
T
E
M
R
P
E
R
Site 32
T204
E
G
K
R
N
Q
T
T
E
M
R
P
E
R
Q
Site 33
T223
E
Q
D
R
A
H
Q
T
G
E
T
V
T
G
S
Site 34
T226
R
A
H
Q
T
G
E
T
V
T
G
S
G
T
Q
Site 35
S230
T
G
E
T
V
T
G
S
G
T
Q
T
Q
A
G
Site 36
T234
V
T
G
S
G
T
Q
T
Q
A
G
A
T
Q
T
Site 37
T241
T
Q
A
G
A
T
Q
T
V
E
Q
D
S
S
H
Site 38
S246
T
Q
T
V
E
Q
D
S
S
H
Q
T
G
R
T
Site 39
S247
Q
T
V
E
Q
D
S
S
H
Q
T
G
R
T
S
Site 40
T250
E
Q
D
S
S
H
Q
T
G
R
T
S
K
Q
T
Site 41
T253
S
S
H
Q
T
G
R
T
S
K
Q
T
Q
E
A
Site 42
S254
S
H
Q
T
G
R
T
S
K
Q
T
Q
E
A
T
Site 43
T257
T
G
R
T
S
K
Q
T
Q
E
A
T
N
D
Q
Site 44
T261
S
K
Q
T
Q
E
A
T
N
D
Q
N
R
G
T
Site 45
T268
T
N
D
Q
N
R
G
T
E
T
H
G
Q
G
R
Site 46
S276
E
T
H
G
Q
G
R
S
Q
T
S
Q
A
V
T
Site 47
T278
H
G
Q
G
R
S
Q
T
S
Q
A
V
T
G
G
Site 48
S279
G
Q
G
R
S
Q
T
S
Q
A
V
T
G
G
H
Site 49
T295
Q
I
Q
A
G
T
H
T
Q
T
P
T
Q
T
V
Site 50
T297
Q
A
G
T
H
T
Q
T
P
T
Q
T
V
E
Q
Site 51
T301
H
T
Q
T
P
T
Q
T
V
E
Q
D
S
S
H
Site 52
S307
Q
T
V
E
Q
D
S
S
H
Q
T
G
S
T
S
Site 53
T310
E
Q
D
S
S
H
Q
T
G
S
T
S
T
Q
T
Site 54
S312
D
S
S
H
Q
T
G
S
T
S
T
Q
T
Q
E
Site 55
T317
T
G
S
T
S
T
Q
T
Q
E
S
T
N
G
Q
Site 56
S320
T
S
T
Q
T
Q
E
S
T
N
G
Q
N
R
G
Site 57
T328
T
N
G
Q
N
R
G
T
E
I
H
G
Q
G
R
Site 58
S336
E
I
H
G
Q
G
R
S
Q
T
S
Q
A
V
T
Site 59
T343
S
Q
T
S
Q
A
V
T
G
G
H
T
Q
I
Q
Site 60
T357
Q
A
G
S
H
T
E
T
V
E
Q
D
R
S
Q
Site 61
S363
E
T
V
E
Q
D
R
S
Q
T
V
S
H
G
G
Site 62
T365
V
E
Q
D
R
S
Q
T
V
S
H
G
G
A
R
Site 63
S367
Q
D
R
S
Q
T
V
S
H
G
G
A
R
E
Q
Site 64
T377
G
A
R
E
Q
G
Q
T
Q
T
Q
P
G
S
G
Site 65
T379
R
E
Q
G
Q
T
Q
T
Q
P
G
S
G
Q
R
Site 66
S391
G
Q
R
W
M
Q
V
S
N
P
E
A
G
E
T
Site 67
T398
S
N
P
E
A
G
E
T
V
P
G
G
Q
A
Q
Site 68
T406
V
P
G
G
Q
A
Q
T
G
A
S
T
E
S
G
Site 69
S409
G
Q
A
Q
T
G
A
S
T
E
S
G
R
Q
E
Site 70
S412
Q
T
G
A
S
T
E
S
G
R
Q
E
W
S
S
Site 71
S419
S
G
R
Q
E
W
S
S
T
H
P
R
R
C
V
Site 72
T420
G
R
Q
E
W
S
S
T
H
P
R
R
C
V
T
Site 73
T427
T
H
P
R
R
C
V
T
E
G
Q
G
D
R
Q
Site 74
T436
G
Q
G
D
R
Q
P
T
V
V
G
E
E
W
V
Site 75
S447
E
E
W
V
D
D
H
S
R
E
T
V
I
L
R
Site 76
T450
V
D
D
H
S
R
E
T
V
I
L
R
L
D
Q
Site 77
S463
D
Q
G
N
L
H
T
S
V
S
S
A
Q
G
Q
Site 78
S465
G
N
L
H
T
S
V
S
S
A
Q
G
Q
D
A
Site 79
S475
Q
G
Q
D
A
A
Q
S
E
E
K
R
G
I
T
Site 80
T482
S
E
E
K
R
G
I
T
A
R
E
L
Y
S
Y
Site 81
Y487
G
I
T
A
R
E
L
Y
S
Y
L
R
S
T
K
Site 82
S488
I
T
A
R
E
L
Y
S
Y
L
R
S
T
K
P
Site 83
Y489
T
A
R
E
L
Y
S
Y
L
R
S
T
K
P
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation