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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
XPR1
Full Name:
Xenotropic and polytropic retrovirus receptor 1
Alias:
Protein SYG1 homolog; Xenotropic and polytropic murine leukemia virus receptor X3
Type:
Mass (Da):
81535
Number AA:
696
UniProt ID:
Q9UBH6
International Prot ID:
IPI00295447
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0004930
PhosphoSite+
KinaseNET
Biological Process:
GO:0007186
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
E
H
L
S
A
H
I
T
P
E
W
R
K
Q
Y
Site 2
Y19
T
P
E
W
R
K
Q
Y
I
Q
Y
E
A
F
K
Site 3
Y30
E
A
F
K
D
M
L
Y
S
A
Q
D
Q
A
P
Site 4
S31
A
F
K
D
M
L
Y
S
A
Q
D
Q
A
P
S
Site 5
S38
S
A
Q
D
Q
A
P
S
V
E
V
T
D
E
D
Site 6
T42
Q
A
P
S
V
E
V
T
D
E
D
T
V
K
R
Site 7
T46
V
E
V
T
D
E
D
T
V
K
R
Y
F
A
K
Site 8
Y50
D
E
D
T
V
K
R
Y
F
A
K
F
E
E
K
Site 9
T71
K
E
L
A
K
I
N
T
F
Y
S
E
K
L
A
Site 10
Y73
L
A
K
I
N
T
F
Y
S
E
K
L
A
E
A
Site 11
T86
E
A
Q
R
R
F
A
T
L
Q
N
E
L
Q
S
Site 12
S94
L
Q
N
E
L
Q
S
S
L
D
A
Q
K
E
S
Site 13
T105
Q
K
E
S
T
G
V
T
T
L
R
Q
R
R
K
Site 14
S118
R
K
P
V
F
H
L
S
H
E
E
R
V
Q
H
Site 15
T169
K
H
D
K
I
L
E
T
S
R
G
A
D
W
R
Site 16
Y186
H
V
E
V
A
P
F
Y
T
C
K
K
I
N
Q
Site 17
T203
S
E
T
E
A
V
V
T
N
E
L
E
D
G
D
Site 18
S264
F
K
L
E
T
D
R
S
I
W
P
L
I
R
I
Site 19
S309
I
F
E
L
N
P
R
S
N
L
S
H
Q
H
L
Site 20
S312
L
N
P
R
S
N
L
S
H
Q
H
L
F
E
I
Site 21
T365
F
L
I
N
P
T
K
T
F
Y
Y
K
S
R
F
Site 22
Y367
I
N
P
T
K
T
F
Y
Y
K
S
R
F
W
L
Site 23
Y368
N
P
T
K
T
F
Y
Y
K
S
R
F
W
L
L
Site 24
S426
L
E
L
K
W
D
E
S
K
G
L
L
P
N
N
Site 25
S434
K
G
L
L
P
N
N
S
E
E
S
G
I
C
H
Site 26
Y443
E
S
G
I
C
H
K
Y
T
Y
G
V
R
A
I
Site 27
Y467
F
I
Q
C
L
R
R
Y
R
D
T
K
R
A
F
Site 28
T470
C
L
R
R
Y
R
D
T
K
R
A
F
P
H
L
Site 29
Y483
H
L
V
N
A
G
K
Y
S
T
T
F
F
M
V
Site 30
T498
T
F
A
A
L
Y
S
T
H
K
E
R
G
H
S
Site 31
T507
K
E
R
G
H
S
D
T
M
V
F
F
Y
L
W
Site 32
T545
D
K
N
A
G
E
N
T
F
L
R
E
E
I
V
Site 33
Y553
F
L
R
E
E
I
V
Y
P
Q
K
A
Y
Y
Y
Site 34
Y559
V
Y
P
Q
K
A
Y
Y
Y
C
A
I
I
E
D
Site 35
T574
V
I
L
R
F
A
W
T
I
Q
I
S
I
T
S
Site 36
T583
Q
I
S
I
T
S
T
T
L
L
P
H
S
G
D
Site 37
T594
H
S
G
D
I
I
A
T
V
F
A
P
L
E
V
Site 38
T640
P
L
N
A
D
D
Q
T
L
L
E
Q
M
M
D
Site 39
S660
R
N
R
Q
K
N
R
S
W
K
Y
N
Q
S
I
Site 40
Y663
Q
K
N
R
S
W
K
Y
N
Q
S
I
S
L
R
Site 41
S666
R
S
W
K
Y
N
Q
S
I
S
L
R
R
P
R
Site 42
S668
W
K
Y
N
Q
S
I
S
L
R
R
P
R
L
A
Site 43
S676
L
R
R
P
R
L
A
S
Q
S
K
A
R
D
T
Site 44
S678
R
P
R
L
A
S
Q
S
K
A
R
D
T
K
V
Site 45
T683
S
Q
S
K
A
R
D
T
K
V
L
I
E
D
T
Site 46
T690
T
K
V
L
I
E
D
T
D
D
E
A
N
T
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation