PhosphoNET

           
Protein Info 
   
Short Name:  HECA
Full Name:  Headcase protein homolog
Alias:  dJ225E12.1; HDC; HDCL; headcase; HHDC
Type: 
Mass (Da):  58837
Number AA:  543
UniProt ID:  Q9UBI9
International Prot ID:  IPI00008202
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0030323     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S18RKNKRANSSGDEQEN
Site 2Y113VDLEKDDYQKVVCNN
Site 3T189QGHLKKDTDWYQVKR
Site 4Y192LKKDTDWYQVKRMQD
Site 5S205QDEKKKKSGSEKNTG
Site 6S207EKKKKSGSEKNTGRP
Site 7T211KSGSEKNTGRPPGEA
Site 8S244HDLPRRHSMDRQNSQ
Site 9S250HSMDRQNSQEKAVGA
Site 10Y260KAVGAAAYGARSPGG
Site 11S264AAAYGARSPGGSPGQ
Site 12S268GARSPGGSPGQSPPT
Site 13S272PGGSPGQSPPTGYSI
Site 14T275SPGQSPPTGYSILSP
Site 15Y277GQSPPTGYSILSPAH
Site 16S278QSPPTGYSILSPAHF
Site 17S281PTGYSILSPAHFSGP
Site 18S286ILSPAHFSGPRSSRY
Site 19S290AHFSGPRSSRYLGEF
Site 20S291HFSGPRSSRYLGEFL
Site 21Y293SGPRSSRYLGEFLKN
Site 22Y324FRNAHFDYSPAGLAV
Site 23S325RNAHFDYSPAGLAVH
Site 24T339HRGGHFDTPVQFLRR
Site 25T354LDLSELLTHIPRHKL
Site 26T363IPRHKLNTFHVRMED
Site 27S421VDGTLFLSPSRHDEI
Site 28S423GTLFLSPSRHDEIEY
Site 29Y430SRHDEIEYDVPCHLQ
Site 30Y510DVRIGMQYFSEYSNV
Site 31Y514GMQYFSEYSNVQQCP
Site 32Y528PHCGNLDYHFVKPFS
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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