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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTRR
Full Name:
Alias:
Type:
Mass (Da):
80410
Number AA:
725
UniProt ID:
Q9UBK8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y35
M
R
R
F
L
L
L
Y
A
T
Q
Q
G
Q
A
Site 2
S66
S
A
D
L
H
C
I
S
E
S
D
K
Y
D
L
Site 3
S68
D
L
H
C
I
S
E
S
D
K
Y
D
L
K
T
Site 4
Y71
C
I
S
E
S
D
K
Y
D
L
K
T
E
T
A
Site 5
T75
S
D
K
Y
D
L
K
T
E
T
A
P
L
V
V
Site 6
T89
V
V
V
S
T
T
G
T
G
D
P
P
D
T
A
Site 7
T95
G
T
G
D
P
P
D
T
A
R
K
F
V
K
E
Site 8
S126
G
L
L
G
L
G
D
S
E
Y
T
Y
F
C
N
Site 9
Y128
L
G
L
G
D
S
E
Y
T
Y
F
C
N
G
G
Site 10
Y130
L
G
D
S
E
Y
T
Y
F
C
N
G
G
K
I
Site 11
Y151
E
L
G
A
R
H
F
Y
D
T
G
H
A
D
D
Site 12
S183
A
L
R
K
H
F
R
S
S
R
G
Q
E
E
I
Site 13
S184
L
R
K
H
F
R
S
S
R
G
Q
E
E
I
S
Site 14
S198
S
G
A
L
P
V
A
S
P
A
S
L
R
T
D
Site 15
S216
S
E
L
L
H
I
E
S
Q
V
E
L
L
R
F
Site 16
S226
E
L
L
R
F
D
D
S
G
R
K
D
S
E
V
Site 17
S231
D
D
S
G
R
K
D
S
E
V
L
K
Q
N
A
Site 18
S254
V
I
E
D
F
E
S
S
L
T
R
S
V
P
P
Site 19
T256
E
D
F
E
S
S
L
T
R
S
V
P
P
L
S
Site 20
S258
F
E
S
S
L
T
R
S
V
P
P
L
S
Q
A
Site 21
S263
T
R
S
V
P
P
L
S
Q
A
S
L
N
I
P
Site 22
Y276
I
P
G
L
P
P
E
Y
L
Q
V
H
L
Q
E
Site 23
S284
L
Q
V
H
L
Q
E
S
L
G
Q
E
E
S
Q
Site 24
S290
E
S
L
G
Q
E
E
S
Q
V
S
V
T
S
A
Site 25
S293
G
Q
E
E
S
Q
V
S
V
T
S
A
D
P
V
Site 26
S296
E
S
Q
V
S
V
T
S
A
D
P
V
F
Q
V
Site 27
S328
L
L
V
E
L
D
I
S
N
T
D
F
S
Y
Q
Site 28
S333
D
I
S
N
T
D
F
S
Y
Q
P
G
D
A
F
Site 29
Y334
I
S
N
T
D
F
S
Y
Q
P
G
D
A
F
S
Site 30
S341
Y
Q
P
G
D
A
F
S
V
I
C
P
N
S
D
Site 31
S347
F
S
V
I
C
P
N
S
D
S
E
V
Q
S
L
Site 32
S349
V
I
C
P
N
S
D
S
E
V
Q
S
L
L
Q
Site 33
S353
N
S
D
S
E
V
Q
S
L
L
Q
R
L
Q
L
Site 34
Y418
F
L
R
A
L
V
D
Y
T
S
D
S
A
E
K
Site 35
S420
R
A
L
V
D
Y
T
S
D
S
A
E
K
R
R
Site 36
S422
L
V
D
Y
T
S
D
S
A
E
K
R
R
L
Q
Site 37
S433
R
R
L
Q
E
L
C
S
K
Q
G
A
A
D
Y
Site 38
Y440
S
K
Q
G
A
A
D
Y
S
R
F
V
R
D
A
Site 39
Y480
P
K
L
Q
P
R
P
Y
S
C
A
S
S
S
L
Site 40
S481
K
L
Q
P
R
P
Y
S
C
A
S
S
S
L
F
Site 41
S484
P
R
P
Y
S
C
A
S
S
S
L
F
H
P
G
Site 42
S485
R
P
Y
S
C
A
S
S
S
L
F
H
P
G
K
Site 43
S486
P
Y
S
C
A
S
S
S
L
F
H
P
G
K
L
Site 44
S535
L
Q
P
N
I
H
A
S
H
E
D
S
G
K
A
Site 45
S539
I
H
A
S
H
E
D
S
G
K
A
L
A
P
K
Site 46
S548
K
A
L
A
P
K
I
S
I
S
P
R
T
T
N
Site 47
S550
L
A
P
K
I
S
I
S
P
R
T
T
N
S
F
Site 48
T553
K
I
S
I
S
P
R
T
T
N
S
F
H
L
P
Site 49
T554
I
S
I
S
P
R
T
T
N
S
F
H
L
P
D
Site 50
S556
I
S
P
R
T
T
N
S
F
H
L
P
D
D
P
Site 51
Y614
C
R
H
K
D
R
D
Y
L
F
R
K
E
L
R
Site 52
S637
T
H
L
K
V
S
F
S
R
D
A
P
V
G
E
Site 53
Y651
E
E
E
A
P
A
K
Y
V
Q
D
N
I
Q
L
Site 54
Y675
L
Q
E
N
G
H
I
Y
V
C
G
D
A
K
N
Site 55
T709
E
K
L
E
A
M
K
T
L
A
T
L
K
E
E
Site 56
Y719
T
L
K
E
E
K
R
Y
L
Q
D
I
W
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation