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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GABBR1
Full Name:
Gamma-aminobutyric acid type B receptor subunit 1 precursor
Alias:
GABA-B receptor; GABA-B receptor 1; GABAB(1e); GABAB, subunit 1c; GABABR1; GABA-B-R1; GABBR1-3; GABR1; Gamma-aminobutyric acid (GABA) B receptor, 1; Gamma-aminobutyric acid type B receptor, subunit 1; Gb1; GPRC3A; HGB1a
Type:
Receptor, GPCR
Mass (Da):
108320
Number AA:
961
UniProt ID:
Q9UBS5
International Prot ID:
IPI00002756
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0005576
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0004930
GO:0004965
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007214
GO:0007194
Phosida
TranscriptoNet
STRING
Kinexus Products
Gamma-aminobutyric acid type B receptor subunit 1 pan-specific antibody AB-NN259-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN259-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
P
G
A
G
G
A
Q
T
P
N
A
T
S
E
G
Site 2
T47
G
I
R
Y
R
G
L
T
R
D
Q
V
K
A
I
Site 3
Y65
P
V
D
Y
E
I
E
Y
V
C
R
G
E
R
E
Site 4
T88
C
L
A
N
G
S
W
T
D
M
D
T
P
S
R
Site 5
T92
G
S
W
T
D
M
D
T
P
S
R
C
V
R
I
Site 6
S101
S
R
C
V
R
I
C
S
K
S
Y
L
T
L
E
Site 7
S103
C
V
R
I
C
S
K
S
Y
L
T
L
E
N
G
Site 8
S140
P
D
F
H
L
V
G
S
S
R
S
I
C
S
Q
Site 9
S141
D
F
H
L
V
G
S
S
R
S
I
C
S
Q
G
Site 10
S143
H
L
V
G
S
S
R
S
I
C
S
Q
G
Q
W
Site 11
S146
G
S
S
R
S
I
C
S
Q
G
Q
W
S
T
P
Site 12
T162
P
H
C
Q
V
N
R
T
P
H
S
E
R
R
A
Site 13
S165
Q
V
N
R
T
P
H
S
E
R
R
A
V
Y
I
Site 14
Y171
H
S
E
R
R
A
V
Y
I
G
A
L
F
P
M
Site 15
S201
M
A
L
E
D
V
N
S
R
R
D
I
L
P
D
Site 16
Y209
R
R
D
I
L
P
D
Y
E
L
K
L
I
H
H
Site 17
S218
L
K
L
I
H
H
D
S
K
C
D
P
G
Q
A
Site 18
Y228
D
P
G
Q
A
T
K
Y
L
Y
E
L
L
Y
N
Site 19
S270
I
V
L
S
Y
G
S
S
S
P
A
L
S
N
R
Site 20
S271
V
L
S
Y
G
S
S
S
P
A
L
S
N
R
Q
Site 21
S275
G
S
S
S
P
A
L
S
N
R
Q
R
F
P
T
Site 22
T282
S
N
R
Q
R
F
P
T
F
F
R
T
H
P
S
Site 23
T286
R
F
P
T
F
F
R
T
H
P
S
A
T
L
H
Site 24
S289
T
F
F
R
T
H
P
S
A
T
L
H
N
P
T
Site 25
T338
K
E
A
G
I
E
I
T
F
R
Q
S
F
F
S
Site 26
S345
T
F
R
Q
S
F
F
S
D
P
A
V
P
V
K
Site 27
Y379
R
K
V
F
C
E
V
Y
K
E
R
L
F
G
K
Site 28
T411
Y
D
P
S
I
N
C
T
V
D
E
M
T
E
A
Site 29
S437
L
N
P
A
N
T
R
S
I
S
N
M
T
S
Q
Site 30
S439
P
A
N
T
R
S
I
S
N
M
T
S
Q
E
F
Site 31
S443
R
S
I
S
N
M
T
S
Q
E
F
V
E
K
L
Site 32
T451
Q
E
F
V
E
K
L
T
K
R
L
K
R
H
P
Site 33
T484
L
A
L
A
L
N
K
T
S
G
G
G
G
R
S
Site 34
S491
T
S
G
G
G
G
R
S
G
V
R
L
E
D
F
Site 35
Y500
V
R
L
E
D
F
N
Y
N
N
Q
T
I
T
D
Site 36
Y510
Q
T
I
T
D
Q
I
Y
R
A
M
N
S
S
S
Site 37
S515
Q
I
Y
R
A
M
N
S
S
S
F
E
G
V
S
Site 38
S516
I
Y
R
A
M
N
S
S
S
F
E
G
V
S
G
Site 39
S517
Y
R
A
M
N
S
S
S
F
E
G
V
S
G
H
Site 40
S530
G
H
V
V
F
D
A
S
G
S
R
M
A
W
T
Site 41
T537
S
G
S
R
M
A
W
T
L
I
E
Q
L
Q
G
Site 42
Y547
E
Q
L
Q
G
G
S
Y
K
K
I
G
Y
Y
D
Site 43
Y553
S
Y
K
K
I
G
Y
Y
D
S
T
K
D
D
L
Site 44
S555
K
K
I
G
Y
Y
D
S
T
K
D
D
L
S
W
Site 45
T556
K
I
G
Y
Y
D
S
T
K
D
D
L
S
W
S
Site 46
S561
D
S
T
K
D
D
L
S
W
S
K
T
D
K
W
Site 47
S563
T
K
D
D
L
S
W
S
K
T
D
K
W
I
G
Site 48
T565
D
D
L
S
W
S
K
T
D
K
W
I
G
G
S
Site 49
S572
T
D
K
W
I
G
G
S
P
P
A
D
Q
T
L
Site 50
T578
G
S
P
P
A
D
Q
T
L
V
I
K
T
F
R
Site 51
T583
D
Q
T
L
V
I
K
T
F
R
F
L
S
Q
K
Site 52
Y621
I
Y
N
S
H
V
R
Y
I
Q
N
S
Q
P
N
Site 53
S625
H
V
R
Y
I
Q
N
S
Q
P
N
L
N
N
L
Site 54
Y652
F
P
L
G
L
D
G
Y
H
I
G
R
N
Q
F
Site 55
T690
T
K
I
W
W
V
H
T
V
F
T
K
K
E
E
Site 56
T704
E
K
K
E
W
R
K
T
L
E
P
W
K
L
Y
Site 57
T740
P
L
H
R
T
I
E
T
F
A
K
E
E
P
K
Site 58
S753
P
K
E
D
I
D
V
S
I
L
P
Q
L
E
H
Site 59
Y776
W
L
G
I
F
Y
G
Y
K
G
L
L
L
L
L
Site 60
T791
G
I
F
L
A
Y
E
T
K
S
V
S
T
E
K
Site 61
S793
F
L
A
Y
E
T
K
S
V
S
T
E
K
I
N
Site 62
T862
P
K
M
R
R
L
I
T
R
G
E
W
Q
S
E
Site 63
S868
I
T
R
G
E
W
Q
S
E
A
Q
D
T
M
K
Site 64
T873
W
Q
S
E
A
Q
D
T
M
K
T
G
S
S
T
Site 65
T876
E
A
Q
D
T
M
K
T
G
S
S
T
N
N
N
Site 66
S879
D
T
M
K
T
G
S
S
T
N
N
N
E
E
E
Site 67
S888
N
N
N
E
E
E
K
S
R
L
L
E
K
E
N
Site 68
S910
A
E
K
E
E
R
V
S
E
L
R
H
Q
L
Q
Site 69
S918
E
L
R
H
Q
L
Q
S
R
Q
Q
L
R
S
R
Site 70
S924
Q
S
R
Q
Q
L
R
S
R
R
H
P
P
T
P
Site 71
T930
R
S
R
R
H
P
P
T
P
P
E
P
S
G
G
Site 72
S950
P
E
P
P
D
R
L
S
C
D
G
S
R
V
H
Site 73
S954
D
R
L
S
C
D
G
S
R
V
H
L
L
Y
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation