PhosphoNET

           
Protein Info 
   
Short Name:  DKK2
Full Name: 
Alias: 
Type: 
Mass (Da):  28447
Number AA:  259
UniProt ID:  Q9UBU2
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S30VESSQIGSSRAKLNS
Site 2S31ESSQIGSSRAKLNSI
Site 3S37SSRAKLNSIKSSLGG
Site 4S40AKLNSIKSSLGGETP
Site 5S41KLNSIKSSLGGETPG
Site 6T46KSSLGGETPGQAANR
Site 7S54PGQAANRSAGMYQGL
Site 8Y58ANRSAGMYQGLAFGG
Site 9S66QGLAFGGSKKGKNLG
Site 10Y76GKNLGQAYPCSSDKE
Site 11S79LGQAYPCSSDKECEV
Site 12S80GQAYPCSSDKECEVG
Site 13Y89KECEVGRYCHSPHQG
Site 14S92EVGRYCHSPHQGSSA
Site 15S97CHSPHQGSSACMVCR
Site 16S98HSPHQGSSACMVCRR
Site 17Y155RDRNHGHYSNHDLGW
Site 18T170QNLGRPHTKMSHIKG
Site 19S173GRPHTKMSHIKGHEG
Site 20S186EGDPCLRSSDCIEGF
Site 21T246CKVWKDATYSSKARL
Site 22Y247KVWKDATYSSKARLH
Site 23S248VWKDATYSSKARLHV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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