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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NXF1
Full Name:
Nuclear RNA export factor 1
Alias:
DKFZp667O0311; MEX67; MRNA export factor TAP; TAP; Tip associating protein; Tip-associated protein
Type:
RNA binding protein
Mass (Da):
70182
Number AA:
619
UniProt ID:
Q9UBU9
International Prot ID:
IPI00033153
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0016607
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0044419
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
A
D
E
G
K
S
Y
S
E
H
D
D
E
R
Site 2
S9
A
D
E
G
K
S
Y
S
E
H
D
D
E
R
V
Site 3
Y33
R
G
P
F
R
W
K
Y
G
E
G
N
R
R
S
Site 4
S40
Y
G
E
G
N
R
R
S
G
R
G
G
S
G
I
Site 5
S45
R
R
S
G
R
G
G
S
G
I
R
S
S
R
L
Site 6
S49
R
G
G
S
G
I
R
S
S
R
L
E
E
D
D
Site 7
S50
G
G
S
G
I
R
S
S
R
L
E
E
D
D
G
Site 8
S62
D
D
G
D
V
A
M
S
D
A
Q
D
G
P
R
Site 9
Y72
Q
D
G
P
R
V
R
Y
N
P
Y
T
T
R
P
Site 10
Y75
P
R
V
R
Y
N
P
Y
T
T
R
P
N
R
R
Site 11
T76
R
V
R
Y
N
P
Y
T
T
R
P
N
R
R
G
Site 12
T85
R
P
N
R
R
G
D
T
W
H
D
R
D
R
I
Site 13
T95
D
R
D
R
I
H
V
T
V
R
R
D
R
A
P
Site 14
T110
P
E
R
G
G
A
G
T
S
Q
D
G
T
S
K
Site 15
S111
E
R
G
G
A
G
T
S
Q
D
G
T
S
K
N
Site 16
T115
A
G
T
S
Q
D
G
T
S
K
N
W
F
K
I
Site 17
Y130
T
I
P
Y
G
R
K
Y
D
K
A
W
L
L
S
Site 18
T148
S
K
C
S
V
P
F
T
P
I
E
F
H
Y
E
Site 19
Y154
F
T
P
I
E
F
H
Y
E
N
T
R
A
Q
F
Site 20
S188
D
R
E
N
R
R
I
S
I
I
I
N
S
S
A
Site 21
S217
E
Q
L
K
L
I
M
S
K
R
Y
D
G
S
Q
Site 22
S223
M
S
K
R
Y
D
G
S
Q
Q
A
L
D
L
K
Site 23
S234
L
D
L
K
G
L
R
S
D
P
D
L
V
A
Q
Site 24
T256
R
R
S
C
M
A
A
T
L
R
I
I
E
E
N
Site 25
S269
E
N
I
P
E
L
L
S
L
N
L
S
N
N
R
Site 26
S273
E
L
L
S
L
N
L
S
N
N
R
L
Y
R
L
Site 27
Y278
N
L
S
N
N
R
L
Y
R
L
D
D
M
S
S
Site 28
S284
L
Y
R
L
D
D
M
S
S
I
V
Q
K
A
P
Site 29
S285
Y
R
L
D
D
M
S
S
I
V
Q
K
A
P
N
Site 30
S305
L
S
G
N
E
L
K
S
E
R
E
L
D
K
I
Site 31
S326
E
L
W
L
D
G
N
S
L
C
D
T
F
R
D
Site 32
T330
D
G
N
S
L
C
D
T
F
R
D
Q
S
T
Y
Site 33
S335
C
D
T
F
R
D
Q
S
T
Y
I
S
A
I
R
Site 34
Y337
T
F
R
D
Q
S
T
Y
I
S
A
I
R
E
R
Site 35
S339
R
D
Q
S
T
Y
I
S
A
I
R
E
R
F
P
Site 36
T369
F
D
V
E
A
P
T
T
L
P
P
C
K
G
S
Site 37
Y377
L
P
P
C
K
G
S
Y
F
G
T
E
N
L
K
Site 38
T380
C
K
G
S
Y
F
G
T
E
N
L
K
S
L
V
Site 39
Y395
L
H
F
L
Q
Q
Y
Y
A
I
Y
D
S
G
D
Site 40
Y398
L
Q
Q
Y
Y
A
I
Y
D
S
G
D
R
Q
G
Site 41
S400
Q
Y
Y
A
I
Y
D
S
G
D
R
Q
G
L
L
Site 42
Y410
R
Q
G
L
L
D
A
Y
H
D
G
A
C
C
S
Site 43
S431
P
Q
N
P
A
R
S
S
L
A
E
Y
F
K
D
Site 44
Y435
A
R
S
S
L
A
E
Y
F
K
D
S
R
N
V
Site 45
T449
V
K
K
L
K
D
P
T
L
R
F
R
L
L
K
Site 46
T472
F
L
N
E
L
P
K
T
Q
H
D
V
N
S
F
Site 47
S478
K
T
Q
H
D
V
N
S
F
V
V
D
I
S
A
Site 48
S506
F
K
E
V
D
G
K
S
R
D
S
L
R
A
F
Site 49
S509
V
D
G
K
S
R
D
S
L
R
A
F
T
R
T
Site 50
T514
R
D
S
L
R
A
F
T
R
T
F
I
A
V
P
Site 51
S540
E
L
F
V
R
N
A
S
S
E
E
I
Q
R
A
Site 52
S556
A
M
P
A
P
T
P
S
S
S
P
V
P
T
L
Site 53
S557
M
P
A
P
T
P
S
S
S
P
V
P
T
L
S
Site 54
S558
P
A
P
T
P
S
S
S
P
V
P
T
L
S
P
Site 55
T562
P
S
S
S
P
V
P
T
L
S
P
E
Q
Q
E
Site 56
S564
S
S
P
V
P
T
L
S
P
E
Q
Q
E
M
L
Site 57
T576
E
M
L
Q
A
F
S
T
Q
S
G
M
N
L
E
Site 58
Y596
L
Q
D
N
N
W
D
Y
T
R
S
A
Q
A
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation