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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SEL1L
Full Name:
Alias:
Suppressor of lin-12-like protein 1
Type:
Mass (Da):
88755
Number AA:
794
UniProt ID:
Q9UBV2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
L
L
S
L
A
S
A
S
S
D
E
E
G
S
Q
Site 2
S23
L
S
L
A
S
A
S
S
D
E
E
G
S
Q
D
Site 3
S28
A
S
S
D
E
E
G
S
Q
D
E
S
L
D
S
Site 4
S32
E
E
G
S
Q
D
E
S
L
D
S
K
T
T
L
Site 5
S35
S
Q
D
E
S
L
D
S
K
T
T
L
T
S
D
Site 6
T37
D
E
S
L
D
S
K
T
T
L
T
S
D
E
S
Site 7
T40
L
D
S
K
T
T
L
T
S
D
E
S
V
K
D
Site 8
S41
D
S
K
T
T
L
T
S
D
E
S
V
K
D
H
Site 9
S44
T
T
L
T
S
D
E
S
V
K
D
H
T
T
A
Site 10
T50
E
S
V
K
D
H
T
T
A
G
R
V
V
A
G
Site 11
S63
A
G
Q
I
F
L
D
S
E
E
S
E
L
E
S
Site 12
S66
I
F
L
D
S
E
E
S
E
L
E
S
S
I
Q
Site 13
S70
S
E
E
S
E
L
E
S
S
I
Q
E
E
E
D
Site 14
S71
E
E
S
E
L
E
S
S
I
Q
E
E
E
D
S
Site 15
S78
S
I
Q
E
E
E
D
S
L
K
S
Q
E
G
E
Site 16
S81
E
E
E
D
S
L
K
S
Q
E
G
E
S
V
T
Site 17
S86
L
K
S
Q
E
G
E
S
V
T
E
D
I
S
F
Site 18
S92
E
S
V
T
E
D
I
S
F
L
E
S
P
N
P
Site 19
S96
E
D
I
S
F
L
E
S
P
N
P
E
N
K
D
Site 20
Y104
P
N
P
E
N
K
D
Y
E
E
P
K
K
V
R
Site 21
T116
K
V
R
K
P
A
L
T
A
I
E
G
T
A
H
Site 22
Y138
F
L
F
L
D
K
E
Y
D
E
C
T
S
D
G
Site 23
S143
K
E
Y
D
E
C
T
S
D
G
R
E
D
G
R
Site 24
Y157
R
L
W
C
A
T
T
Y
D
Y
K
A
D
E
K
Site 25
S197
G
M
K
I
L
N
G
S
N
K
K
S
Q
K
R
Site 26
S201
L
N
G
S
N
K
K
S
Q
K
R
E
A
Y
R
Site 27
Y207
K
S
Q
K
R
E
A
Y
R
Y
L
Q
K
A
A
Site 28
Y209
Q
K
R
E
A
Y
R
Y
L
Q
K
A
A
S
M
Site 29
S215
R
Y
L
Q
K
A
A
S
M
N
H
T
K
A
L
Site 30
T219
K
A
A
S
M
N
H
T
K
A
L
E
R
V
S
Site 31
T250
R
E
M
F
E
K
L
T
E
E
G
S
P
K
G
Site 32
S254
E
K
L
T
E
E
G
S
P
K
G
Q
T
A
L
Site 33
T259
E
G
S
P
K
G
Q
T
A
L
G
F
L
Y
A
Site 34
T316
Q
S
C
E
S
A
L
T
H
Y
R
L
V
A
N
Site 35
Y363
L
E
E
D
L
I
Q
Y
Y
Q
F
L
A
E
K
Site 36
Y364
E
E
D
L
I
Q
Y
Y
Q
F
L
A
E
K
G
Site 37
Y400
N
H
Q
R
A
F
D
Y
F
N
L
A
A
N
A
Site 38
S424
G
K
M
Y
S
E
G
S
D
I
V
P
Q
S
N
Site 39
S430
G
S
D
I
V
P
Q
S
N
E
T
A
L
H
Y
Site 40
Y437
S
N
E
T
A
L
H
Y
F
K
K
A
A
D
M
Site 41
Y457
Q
S
G
L
G
M
A
Y
L
Y
G
R
G
V
Q
Site 42
Y467
G
R
G
V
Q
V
N
Y
D
L
A
L
K
Y
F
Site 43
Y473
N
Y
D
L
A
L
K
Y
F
Q
K
A
A
E
Q
Site 44
Y493
Q
L
Q
L
G
S
M
Y
Y
N
G
I
G
V
K
Site 45
Y494
L
Q
L
G
S
M
Y
Y
N
G
I
G
V
K
R
Site 46
Y503
G
I
G
V
K
R
D
Y
K
Q
A
L
K
Y
F
Site 47
Y509
D
Y
K
Q
A
L
K
Y
F
N
L
A
S
Q
G
Site 48
S531
N
L
A
Q
M
H
A
S
G
T
G
V
M
R
S
Site 49
T561
R
W
S
E
R
L
M
T
A
Y
N
S
Y
K
D
Site 50
Y563
S
E
R
L
M
T
A
Y
N
S
Y
K
D
G
D
Site 51
Y571
N
S
Y
K
D
G
D
Y
N
A
A
V
I
Q
Y
Site 52
Y586
L
L
L
A
E
Q
G
Y
E
V
A
Q
S
N
A
Site 53
S591
Q
G
Y
E
V
A
Q
S
N
A
A
F
I
L
D
Site 54
S603
I
L
D
Q
R
E
A
S
I
V
G
E
N
E
T
Site 55
T610
S
I
V
G
E
N
E
T
Y
P
R
A
L
L
H
Site 56
Y611
I
V
G
E
N
E
T
Y
P
R
A
L
L
H
W
Site 57
S623
L
H
W
N
R
A
A
S
Q
G
Y
T
V
A
R
Site 58
T627
R
A
A
S
Q
G
Y
T
V
A
R
I
K
L
G
Site 59
Y636
A
R
I
K
L
G
D
Y
H
F
Y
G
F
G
T
Site 60
Y647
G
F
G
T
D
V
D
Y
E
T
A
F
I
H
Y
Site 61
T649
G
T
D
V
D
Y
E
T
A
F
I
H
Y
R
L
Site 62
S658
F
I
H
Y
R
L
A
S
E
Q
Q
H
S
A
Q
Site 63
Y672
Q
A
M
F
N
L
G
Y
M
H
E
K
G
L
G
Site 64
Y691
I
H
L
A
K
R
F
Y
D
M
A
A
E
A
S
Site 65
S698
Y
D
M
A
A
E
A
S
P
D
A
Q
V
P
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation