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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PEF1
Full Name:
Peflin
Alias:
Abp32; Pef; Pef1; Pef1a; Penta-ef-hand domain containing 1
Type:
Uncharacterized protein; Membrane, cytoplasm
Mass (Da):
30381
Number AA:
284
UniProt ID:
Q9UBV8
International Prot ID:
IPI00018235
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0019898
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0046982
PhosphoSite+
KinaseNET
Biological Process:
GO:0051592
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
A
P
G
A
P
P
G
S
Y
Y
P
G
P
P
N
Site 2
Y25
P
G
A
P
P
G
S
Y
Y
P
G
P
P
N
S
Site 3
Y26
G
A
P
P
G
S
Y
Y
P
G
P
P
N
S
G
Site 4
S32
Y
Y
P
G
P
P
N
S
G
G
Q
Y
G
S
G
Site 5
Y36
P
P
N
S
G
G
Q
Y
G
S
G
L
P
P
G
Site 6
S38
N
S
G
G
Q
Y
G
S
G
L
P
P
G
G
G
Site 7
Y46
G
L
P
P
G
G
G
Y
G
G
P
A
P
G
G
Site 8
Y55
G
P
A
P
G
G
P
Y
G
P
P
A
G
G
G
Site 9
Y64
P
P
A
G
G
G
P
Y
G
H
P
N
P
G
M
Site 10
S74
P
N
P
G
M
F
P
S
G
T
P
G
G
P
Y
Site 11
T76
P
G
M
F
P
S
G
T
P
G
G
P
Y
G
G
Site 12
Y81
S
G
T
P
G
G
P
Y
G
G
A
A
P
G
G
Site 13
Y90
G
A
A
P
G
G
P
Y
G
Q
P
P
P
S
S
Site 14
S96
P
Y
G
Q
P
P
P
S
S
Y
G
A
Q
Q
P
Site 15
S97
Y
G
Q
P
P
P
S
S
Y
G
A
Q
Q
P
G
Site 16
Y98
G
Q
P
P
P
S
S
Y
G
A
Q
Q
P
G
L
Site 17
Y106
G
A
Q
Q
P
G
L
Y
G
Q
G
G
A
P
P
Site 18
S121
N
V
D
P
E
A
Y
S
W
F
Q
S
V
D
S
Site 19
S125
E
A
Y
S
W
F
Q
S
V
D
S
D
H
S
G
Site 20
S128
S
W
F
Q
S
V
D
S
D
H
S
G
Y
I
S
Site 21
S131
Q
S
V
D
S
D
H
S
G
Y
I
S
M
K
E
Site 22
Y133
V
D
S
D
H
S
G
Y
I
S
M
K
E
L
K
Site 23
S135
S
D
H
S
G
Y
I
S
M
K
E
L
K
Q
A
Site 24
T166
M
I
N
M
F
D
K
T
K
S
G
R
I
D
V
Site 25
Y174
K
S
G
R
I
D
V
Y
G
F
S
A
L
W
K
Site 26
Y193
W
K
N
L
F
Q
Q
Y
D
R
D
R
S
G
S
Site 27
S198
Q
Q
Y
D
R
D
R
S
G
S
I
S
Y
T
E
Site 28
S200
Y
D
R
D
R
S
G
S
I
S
Y
T
E
L
Q
Site 29
S202
R
D
R
S
G
S
I
S
Y
T
E
L
Q
Q
A
Site 30
T204
R
S
G
S
I
S
Y
T
E
L
Q
Q
A
L
S
Site 31
S211
T
E
L
Q
Q
A
L
S
Q
M
G
Y
N
L
S
Site 32
S218
S
Q
M
G
Y
N
L
S
P
Q
F
T
Q
L
L
Site 33
T222
Y
N
L
S
P
Q
F
T
Q
L
L
V
S
R
Y
Site 34
Y229
T
Q
L
L
V
S
R
Y
C
P
R
S
A
N
P
Site 35
S233
V
S
R
Y
C
P
R
S
A
N
P
A
M
Q
L
Site 36
T262
E
A
F
R
E
K
D
T
A
V
Q
G
N
I
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation