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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZMYM2
Full Name:
Similar to zinc finger MYM-type protein 5
Alias:
FIM; Fused in myeloproliferative disorders protein; MYM; RAMP; Rearranged in atypical myeloproliferative disorder protein; Z198; Zinc finger protein 198; Zinc finger, MYM-type 2; ZN198; ZNF198
Type:
Uncharacterized protein
Mass (Da):
154911
Number AA:
1377
UniProt ID:
Q9UBW7
International Prot ID:
IPI00294603
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016605
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0031624
GO:0008270
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
G
S
T
A
M
A
T
S
L
T
N
V
G
N
S
Site 2
S34
S
L
T
N
V
G
N
S
F
S
G
P
A
N
P
Site 3
S36
T
N
V
G
N
S
F
S
G
P
A
N
P
L
V
Site 4
S44
G
P
A
N
P
L
V
S
R
S
N
K
F
Q
N
Site 5
S46
A
N
P
L
V
S
R
S
N
K
F
Q
N
S
S
Site 6
S53
S
N
K
F
Q
N
S
S
V
E
D
D
D
D
V
Site 7
S72
P
V
Q
P
P
P
P
S
V
P
V
V
A
D
Q
Site 8
T81
P
V
V
A
D
Q
R
T
I
T
F
T
S
S
K
Site 9
T83
V
A
D
Q
R
T
I
T
F
T
S
S
K
N
E
Site 10
T85
D
Q
R
T
I
T
F
T
S
S
K
N
E
E
L
Site 11
S87
R
T
I
T
F
T
S
S
K
N
E
E
L
Q
G
Site 12
S97
E
E
L
Q
G
N
D
S
K
I
T
P
S
S
K
Site 13
T100
Q
G
N
D
S
K
I
T
P
S
S
K
E
L
A
Site 14
S103
D
S
K
I
T
P
S
S
K
E
L
A
S
Q
K
Site 15
S108
P
S
S
K
E
L
A
S
Q
K
G
S
V
S
E
Site 16
S114
A
S
Q
K
G
S
V
S
E
T
I
V
I
D
D
Site 17
T116
Q
K
G
S
V
S
E
T
I
V
I
D
D
E
E
Site 18
T127
D
D
E
E
D
M
E
T
N
Q
G
Q
E
K
N
Site 19
S136
Q
G
Q
E
K
N
S
S
N
F
I
E
R
R
P
Site 20
T146
I
E
R
R
P
P
E
T
K
N
R
T
N
D
V
Site 21
S156
R
T
N
D
V
D
F
S
T
S
S
F
S
R
S
Site 22
T157
T
N
D
V
D
F
S
T
S
S
F
S
R
S
K
Site 23
S158
N
D
V
D
F
S
T
S
S
F
S
R
S
K
V
Site 24
S159
D
V
D
F
S
T
S
S
F
S
R
S
K
V
N
Site 25
S161
D
F
S
T
S
S
F
S
R
S
K
V
N
A
G
Site 26
S163
S
T
S
S
F
S
R
S
K
V
N
A
G
M
G
Site 27
T176
M
G
N
S
G
I
T
T
E
P
D
S
E
I
Q
Site 28
S180
G
I
T
T
E
P
D
S
E
I
Q
I
A
N
V
Site 29
S195
T
T
L
E
T
G
V
S
S
V
N
D
G
Q
L
Site 30
S196
T
L
E
T
G
V
S
S
V
N
D
G
Q
L
E
Site 31
T215
R
D
M
N
L
M
I
T
H
V
T
S
L
Q
N
Site 32
T223
H
V
T
S
L
Q
N
T
N
L
G
D
V
S
N
Site 33
S229
N
T
N
L
G
D
V
S
N
G
L
Q
S
S
N
Site 34
S235
V
S
N
G
L
Q
S
S
N
F
G
V
N
I
Q
Site 35
T243
N
F
G
V
N
I
Q
T
Y
T
P
S
L
T
S
Site 36
Y244
F
G
V
N
I
Q
T
Y
T
P
S
L
T
S
Q
Site 37
T245
G
V
N
I
Q
T
Y
T
P
S
L
T
S
Q
T
Site 38
S247
N
I
Q
T
Y
T
P
S
L
T
S
Q
T
K
T
Site 39
S250
T
Y
T
P
S
L
T
S
Q
T
K
T
G
V
G
Site 40
T254
S
L
T
S
Q
T
K
T
G
V
G
P
F
N
P
Site 41
S284
A
T
H
H
N
P
D
S
W
I
S
Q
S
A
S
Site 42
S287
H
N
P
D
S
W
I
S
Q
S
A
S
F
P
R
Site 43
S289
P
D
S
W
I
S
Q
S
A
S
F
P
R
N
Q
Site 44
S291
S
W
I
S
Q
S
A
S
F
P
R
N
Q
K
Q
Site 45
S303
Q
K
Q
P
G
V
D
S
L
S
P
V
A
S
L
Site 46
S305
Q
P
G
V
D
S
L
S
P
V
A
S
L
P
K
Site 47
S309
D
S
L
S
P
V
A
S
L
P
K
Q
I
F
Q
Site 48
S318
P
K
Q
I
F
Q
P
S
V
Q
Q
Q
P
T
K
Site 49
T343
K
P
L
Q
K
G
Q
T
A
Y
Q
R
K
G
S
Site 50
Y345
L
Q
K
G
Q
T
A
Y
Q
R
K
G
S
A
H
Site 51
S350
T
A
Y
Q
R
K
G
S
A
H
L
F
C
S
T
Site 52
S361
F
C
S
T
T
C
L
S
S
F
S
H
K
P
A
Site 53
S362
C
S
T
T
C
L
S
S
F
S
H
K
P
A
P
Site 54
S364
T
T
C
L
S
S
F
S
H
K
P
A
P
K
K
Site 55
S393
T
I
V
A
Q
V
D
S
S
E
S
F
Q
E
F
Site 56
S396
A
Q
V
D
S
S
E
S
F
Q
E
F
C
S
T
Site 57
S402
E
S
F
Q
E
F
C
S
T
S
C
L
S
L
Y
Site 58
T403
S
F
Q
E
F
C
S
T
S
C
L
S
L
Y
E
Site 59
S407
F
C
S
T
S
C
L
S
L
Y
E
D
K
Q
N
Site 60
Y409
S
T
S
C
L
S
L
Y
E
D
K
Q
N
P
T
Site 61
S423
T
K
G
A
L
N
K
S
R
C
T
I
C
G
K
Site 62
T426
A
L
N
K
S
R
C
T
I
C
G
K
L
T
E
Site 63
Y456
S
D
H
C
F
N
R
Y
R
M
A
N
G
L
I
Site 64
Y473
C
C
E
Q
C
G
E
Y
L
P
S
K
G
A
G
Site 65
S476
Q
C
G
E
Y
L
P
S
K
G
A
G
N
N
V
Site 66
Y502
C
Q
S
C
V
S
E
Y
K
Q
V
G
S
H
P
Site 67
S507
S
E
Y
K
Q
V
G
S
H
P
S
F
L
K
E
Site 68
S510
K
Q
V
G
S
H
P
S
F
L
K
E
V
R
D
Site 69
S522
V
R
D
H
M
Q
D
S
F
L
M
Q
P
E
K
Site 70
Y557
Q
C
I
G
P
N
G
Y
M
E
P
Y
C
S
T
Site 71
T572
A
C
M
N
S
H
K
T
K
Y
A
K
S
Q
S
Site 72
Y574
M
N
S
H
K
T
K
Y
A
K
S
Q
S
L
G
Site 73
S577
H
K
T
K
Y
A
K
S
Q
S
L
G
I
I
C
Site 74
S579
T
K
Y
A
K
S
Q
S
L
G
I
I
C
H
F
Site 75
Y595
K
R
N
S
L
P
Q
Y
Q
A
T
M
P
D
G
Site 76
T598
S
L
P
Q
Y
Q
A
T
M
P
D
G
K
L
Y
Site 77
Y605
T
M
P
D
G
K
L
Y
N
F
C
N
S
S
C
Site 78
S610
K
L
Y
N
F
C
N
S
S
C
V
A
K
F
Q
Site 79
S620
V
A
K
F
Q
A
L
S
M
Q
S
S
P
N
G
Site 80
S624
Q
A
L
S
M
Q
S
S
P
N
G
Q
F
V
A
Site 81
T666
V
H
Q
F
C
S
K
T
C
S
D
D
Y
K
K
Site 82
Y671
S
K
T
C
S
D
D
Y
K
K
L
H
C
I
V
Site 83
Y680
K
L
H
C
I
V
T
Y
C
E
Y
C
Q
E
E
Site 84
Y683
C
I
V
T
Y
C
E
Y
C
Q
E
E
K
T
L
Site 85
T689
E
Y
C
Q
E
E
K
T
L
H
E
T
V
N
F
Site 86
T693
E
E
K
T
L
H
E
T
V
N
F
S
G
V
K
Site 87
Y712
S
E
G
C
K
L
L
Y
K
Q
D
F
A
R
R
Site 88
Y729
L
R
C
V
T
C
N
Y
C
S
Q
L
C
K
K
Site 89
Y762
C
K
K
F
Q
D
W
Y
Y
K
A
A
R
C
D
Site 90
S773
A
R
C
D
C
C
K
S
Q
G
T
L
K
E
R
Site 91
T809
Q
Q
N
E
P
N
M
T
T
Q
K
G
P
E
N
Site 92
Y819
K
G
P
E
N
L
H
Y
D
Q
G
C
Q
T
S
Site 93
S826
Y
D
Q
G
C
Q
T
S
R
T
K
M
T
G
S
Site 94
T828
Q
G
C
Q
T
S
R
T
K
M
T
G
S
A
P
Site 95
T831
Q
T
S
R
T
K
M
T
G
S
A
P
P
P
S
Site 96
S833
S
R
T
K
M
T
G
S
A
P
P
P
S
P
T
Site 97
S838
T
G
S
A
P
P
P
S
P
T
P
N
K
E
M
Site 98
T840
S
A
P
P
P
S
P
T
P
N
K
E
M
K
N
Site 99
Y862
L
T
M
T
K
A
T
Y
C
K
P
H
M
Q
T
Site 100
T877
K
S
C
Q
T
D
D
T
W
R
T
E
Y
V
P
Site 101
Y882
D
D
T
W
R
T
E
Y
V
P
V
P
I
P
V
Site 102
S939
A
A
I
E
E
L
K
S
K
V
S
S
D
A
L
Site 103
S943
E
L
K
S
K
V
S
S
D
A
L
D
T
E
L
Site 104
S958
L
T
M
T
D
M
M
S
E
D
E
G
K
T
E
Site 105
S987
G
S
D
L
L
K
N
S
D
P
E
T
Q
S
S
Site 106
T991
L
K
N
S
D
P
E
T
Q
S
S
M
P
D
V
Site 107
S993
N
S
D
P
E
T
Q
S
S
M
P
D
V
P
Y
Site 108
S994
S
D
P
E
T
Q
S
S
M
P
D
V
P
Y
E
Site 109
Y1000
S
S
M
P
D
V
P
Y
E
P
D
L
D
I
E
Site 110
Y1033
P
P
V
F
G
E
E
Y
E
E
Q
P
R
P
R
Site 111
S1041
E
E
Q
P
R
P
R
S
K
K
K
G
A
K
R
Site 112
S1052
G
A
K
R
K
A
V
S
G
Y
Q
S
H
D
D
Site 113
S1056
K
A
V
S
G
Y
Q
S
H
D
D
S
S
D
N
Site 114
S1060
G
Y
Q
S
H
D
D
S
S
D
N
S
E
C
S
Site 115
S1061
Y
Q
S
H
D
D
S
S
D
N
S
E
C
S
F
Site 116
S1064
H
D
D
S
S
D
N
S
E
C
S
F
P
F
K
Site 117
S1067
S
S
D
N
S
E
C
S
F
P
F
K
Y
T
Y
Site 118
Y1074
S
F
P
F
K
Y
T
Y
G
V
N
A
W
K
H
Site 119
S1100
L
V
L
D
E
L
K
S
S
K
S
V
K
L
K
Site 120
S1101
V
L
D
E
L
K
S
S
K
S
V
K
L
K
E
Site 121
S1103
D
E
L
K
S
S
K
S
V
K
L
K
E
D
L
Site 122
S1112
K
L
K
E
D
L
L
S
H
T
T
A
E
L
N
Site 123
T1114
K
E
D
L
L
S
H
T
T
A
E
L
N
Y
G
Site 124
Y1137
R
R
P
N
G
E
N
Y
A
P
D
S
I
Y
Y
Site 125
Y1152
L
C
L
G
I
Q
E
Y
L
C
G
S
N
R
K
Site 126
Y1168
N
I
F
I
D
P
G
Y
Q
T
F
E
Q
E
L
Site 127
T1170
F
I
D
P
G
Y
Q
T
F
E
Q
E
L
N
K
Site 128
S1181
E
L
N
K
I
L
R
S
W
Q
P
S
I
L
P
Site 129
S1185
I
L
R
S
W
Q
P
S
I
L
P
D
G
S
I
Site 130
S1191
P
S
I
L
P
D
G
S
I
F
S
R
V
E
E
Site 131
Y1200
F
S
R
V
E
E
D
Y
L
W
R
I
K
Q
L
Site 132
T1218
S
P
V
A
L
L
N
T
L
F
Y
F
N
T
K
Site 133
Y1221
A
L
L
N
T
L
F
Y
F
N
T
K
Y
F
G
Site 134
T1224
N
T
L
F
Y
F
N
T
K
Y
F
G
L
K
T
Site 135
T1231
T
K
Y
F
G
L
K
T
V
E
Q
H
L
R
L
Site 136
S1239
V
E
Q
H
L
R
L
S
F
G
T
V
F
R
H
Site 137
T1242
H
L
R
L
S
F
G
T
V
F
R
H
W
K
K
Site 138
T1253
H
W
K
K
N
P
L
T
M
E
N
K
A
C
L
Site 139
Y1262
E
N
K
A
C
L
R
Y
Q
V
S
S
L
C
G
Site 140
S1265
A
C
L
R
Y
Q
V
S
S
L
C
G
T
D
N
Site 141
S1266
C
L
R
Y
Q
V
S
S
L
C
G
T
D
N
E
Site 142
T1270
Q
V
S
S
L
C
G
T
D
N
E
D
K
I
T
Site 143
T1277
T
D
N
E
D
K
I
T
T
G
K
R
K
H
E
Site 144
T1296
V
F
E
Q
I
E
N
T
A
N
P
S
R
C
P
Site 145
Y1310
P
V
K
M
F
E
C
Y
L
S
K
S
P
Q
N
Site 146
S1314
F
E
C
Y
L
S
K
S
P
Q
N
L
N
Q
R
Site 147
Y1326
N
Q
R
M
D
V
F
Y
L
Q
P
E
C
S
S
Site 148
S1332
F
Y
L
Q
P
E
C
S
S
S
T
D
S
P
V
Site 149
S1333
Y
L
Q
P
E
C
S
S
S
T
D
S
P
V
W
Site 150
S1334
L
Q
P
E
C
S
S
S
T
D
S
P
V
W
Y
Site 151
T1335
Q
P
E
C
S
S
S
T
D
S
P
V
W
Y
T
Site 152
S1337
E
C
S
S
S
T
D
S
P
V
W
Y
T
S
T
Site 153
Y1341
S
T
D
S
P
V
W
Y
T
S
T
S
L
D
R
Site 154
S1343
D
S
P
V
W
Y
T
S
T
S
L
D
R
N
T
Site 155
S1345
P
V
W
Y
T
S
T
S
L
D
R
N
T
L
E
Site 156
T1350
S
T
S
L
D
R
N
T
L
E
N
M
L
V
R
Site 157
Y1365
V
L
L
V
K
D
I
Y
D
K
D
N
Y
E
L
Site 158
Y1370
D
I
Y
D
K
D
N
Y
E
L
D
E
D
T
D
Site 159
T1376
N
Y
E
L
D
E
D
T
D
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation