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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CTSF
Full Name:
Cathepsin F
Alias:
CATF; CATSF; EC 3.4.22.41
Type:
Mass (Da):
53366
Number AA:
484
UniProt ID:
Q9UBX1
International Prot ID:
IPI00002816
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005764
Uniprot
OncoNet
Molecular Function:
GO:0004197
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
P
A
Q
P
R
A
A
S
F
Q
A
W
G
P
P
Site 2
S36
F
Q
A
W
G
P
P
S
P
E
L
L
A
P
T
Site 3
S76
V
R
R
A
G
Q
G
S
L
Y
S
L
E
A
T
Site 4
S79
A
G
Q
G
S
L
Y
S
L
E
A
T
L
E
E
Site 5
T83
S
L
Y
S
L
E
A
T
L
E
E
P
P
C
N
Site 6
T129
K
D
C
G
P
V
D
T
K
V
P
G
A
G
E
Site 7
S139
P
G
A
G
E
P
K
S
A
F
T
Q
G
S
A
Site 8
S145
K
S
A
F
T
Q
G
S
A
M
I
S
S
L
S
Site 9
S149
T
Q
G
S
A
M
I
S
S
L
S
Q
N
H
P
Site 10
S150
Q
G
S
A
M
I
S
S
L
S
Q
N
H
P
D
Site 11
S152
S
A
M
I
S
S
L
S
Q
N
H
P
D
N
R
Site 12
T162
H
P
D
N
R
N
E
T
F
S
S
V
I
S
L
Site 13
S164
D
N
R
N
E
T
F
S
S
V
I
S
L
L
N
Site 14
S165
N
R
N
E
T
F
S
S
V
I
S
L
L
N
E
Site 15
S176
L
L
N
E
D
P
L
S
Q
D
L
P
V
K
M
Site 16
Y194
F
K
N
F
V
I
T
Y
N
R
T
Y
E
S
K
Site 17
Y198
V
I
T
Y
N
R
T
Y
E
S
K
E
E
A
R
Site 18
T228
I
Q
A
L
D
R
G
T
A
Q
Y
G
V
T
K
Site 19
Y231
L
D
R
G
T
A
Q
Y
G
V
T
K
F
S
D
Site 20
T240
V
T
K
F
S
D
L
T
E
E
E
F
R
T
I
Site 21
Y248
E
E
E
F
R
T
I
Y
L
N
T
L
L
R
K
Site 22
S266
N
K
M
K
Q
A
K
S
V
G
D
L
A
P
P
Site 23
S279
P
P
E
W
D
W
R
S
K
G
A
V
T
K
V
Site 24
S319
Q
G
T
L
L
S
L
S
E
Q
E
L
L
D
C
Site 25
Y342
G
G
L
P
S
N
A
Y
S
A
I
K
N
L
G
Site 26
S343
G
L
P
S
N
A
Y
S
A
I
K
N
L
G
G
Site 27
T353
K
N
L
G
G
L
E
T
E
D
D
Y
S
Y
Q
Site 28
Y357
G
L
E
T
E
D
D
Y
S
Y
Q
G
H
M
Q
Site 29
S358
L
E
T
E
D
D
Y
S
Y
Q
G
H
M
Q
S
Site 30
Y359
E
T
E
D
D
Y
S
Y
Q
G
H
M
Q
S
C
Site 31
S365
S
Y
Q
G
H
M
Q
S
C
N
F
S
A
E
K
Site 32
Y376
S
A
E
K
A
K
V
Y
I
N
D
S
V
E
L
Site 33
S380
A
K
V
Y
I
N
D
S
V
E
L
S
Q
N
E
Site 34
S384
I
N
D
S
V
E
L
S
Q
N
E
Q
K
L
A
Site 35
S425
R
P
L
R
P
L
C
S
P
W
L
I
D
H
A
Site 36
Y463
D
W
G
E
K
G
Y
Y
Y
L
H
R
G
S
G
Site 37
Y464
W
G
E
K
G
Y
Y
Y
L
H
R
G
S
G
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation