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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AASS
Full Name:
Alpha-aminoadipic semialdehyde synthase, mitochondrial precursor
Alias:
LKR/SDH
Type:
Mass (Da):
102113
Number AA:
926
UniProt ID:
Q9UDR5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0047131
GO:0047130
PhosphoSite+
KinaseNET
Biological Process:
GO:0055114
GO:0051262
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
G
L
G
R
L
G
V
S
L
S
K
G
L
H
H
Site 2
S17
G
R
L
G
V
S
L
S
K
G
L
H
H
K
A
Site 3
T51
P
K
H
I
K
G
I
T
N
L
G
Y
K
V
L
Site 4
Y55
K
G
I
T
N
L
G
Y
K
V
L
I
Q
P
S
Site 5
S62
Y
K
V
L
I
Q
P
S
N
R
R
A
I
H
D
Site 6
Y72
R
A
I
H
D
K
D
Y
V
K
A
G
G
I
L
Site 7
T105
E
K
L
M
S
R
K
T
Y
A
F
F
S
H
T
Site 8
Y106
K
L
M
S
R
K
T
Y
A
F
F
S
H
T
I
Site 9
S110
R
K
T
Y
A
F
F
S
H
T
I
K
A
Q
E
Site 10
Y136
Q
E
I
R
L
I
D
Y
E
K
M
V
D
H
R
Site 11
Y188
H
I
G
M
A
H
N
Y
R
N
S
S
Q
A
V
Site 12
S191
M
A
H
N
Y
R
N
S
S
Q
A
V
Q
A
V
Site 13
S192
A
H
N
Y
R
N
S
S
Q
A
V
Q
A
V
R
Site 14
S206
R
D
A
G
Y
E
I
S
L
G
L
M
P
K
S
Site 15
Y242
F
N
E
L
P
C
E
Y
V
E
P
H
E
L
K
Site 16
S252
P
H
E
L
K
E
V
S
Q
T
G
D
L
R
K
Site 17
T254
E
L
K
E
V
S
Q
T
G
D
L
R
K
V
Y
Site 18
Y261
T
G
D
L
R
K
V
Y
G
T
V
L
S
R
H
Site 19
T263
D
L
R
K
V
Y
G
T
V
L
S
R
H
H
H
Site 20
S266
K
V
Y
G
T
V
L
S
R
H
H
H
L
V
R
Site 21
T275
H
H
H
L
V
R
K
T
D
A
V
Y
D
P
A
Site 22
Y279
V
R
K
T
D
A
V
Y
D
P
A
E
Y
D
K
Site 23
Y291
Y
D
K
H
P
E
R
Y
I
S
R
F
N
T
D
Site 24
S293
K
H
P
E
R
Y
I
S
R
F
N
T
D
I
A
Site 25
T297
R
Y
I
S
R
F
N
T
D
I
A
P
Y
T
T
Site 26
Y311
T
C
L
I
N
G
I
Y
W
E
Q
N
T
P
R
Site 27
T316
G
I
Y
W
E
Q
N
T
P
R
L
L
T
R
Q
Site 28
T321
Q
N
T
P
R
L
L
T
R
Q
D
A
Q
S
L
Site 29
S327
L
T
R
Q
D
A
Q
S
L
L
A
P
G
K
F
Site 30
T367
G
G
S
I
E
F
M
T
E
C
T
T
I
E
H
Site 31
S389
D
Q
H
I
I
H
D
S
V
E
G
S
G
I
L
Site 32
S429
Y
V
E
E
M
I
L
S
D
A
T
Q
P
L
E
Site 33
T432
E
M
I
L
S
D
A
T
Q
P
L
E
S
Q
N
Site 34
S437
D
A
T
Q
P
L
E
S
Q
N
F
S
P
V
V
Site 35
S441
P
L
E
S
Q
N
F
S
P
V
V
R
D
A
V
Site 36
Y459
N
G
T
L
P
D
K
Y
K
Y
I
Q
T
L
R
Site 37
Y461
T
L
P
D
K
Y
K
Y
I
Q
T
L
R
E
S
Site 38
T464
D
K
Y
K
Y
I
Q
T
L
R
E
S
R
E
R
Site 39
S468
Y
I
Q
T
L
R
E
S
R
E
R
A
Q
S
L
Site 40
S474
E
S
R
E
R
A
Q
S
L
S
M
G
T
R
R
Site 41
S476
R
E
R
A
Q
S
L
S
M
G
T
R
R
K
V
Site 42
T479
A
Q
S
L
S
M
G
T
R
R
K
V
L
V
L
Site 43
Y498
I
S
E
P
V
L
E
Y
L
S
R
D
G
N
I
Site 44
T508
R
D
G
N
I
E
I
T
V
G
S
D
M
K
N
Site 45
Y556
L
V
I
S
L
L
P
Y
V
L
H
P
L
V
A
Site 46
S589
A
L
K
E
L
E
K
S
V
E
D
A
G
I
T
Site 47
T625
K
A
K
E
V
G
A
T
I
E
S
Y
I
S
Y
Site 48
S642
G
L
P
A
P
E
H
S
N
N
P
L
R
Y
K
Site 49
S651
N
P
L
R
Y
K
F
S
W
S
P
V
G
V
L
Site 50
Y700
P
G
L
N
L
E
G
Y
P
N
R
D
S
T
K
Site 51
S705
E
G
Y
P
N
R
D
S
T
K
Y
A
E
I
Y
Site 52
T706
G
Y
P
N
R
D
S
T
K
Y
A
E
I
Y
G
Site 53
Y708
P
N
R
D
S
T
K
Y
A
E
I
Y
G
I
S
Site 54
Y712
S
T
K
Y
A
E
I
Y
G
I
S
S
A
H
T
Site 55
T719
Y
G
I
S
S
A
H
T
L
L
R
G
T
L
R
Site 56
T724
A
H
T
L
L
R
G
T
L
R
Y
K
G
Y
M
Site 57
Y727
L
L
R
G
T
L
R
Y
K
G
Y
M
K
A
L
Site 58
Y730
G
T
L
R
Y
K
G
Y
M
K
A
L
N
G
F
Site 59
T759
R
P
E
A
N
P
L
T
W
K
Q
L
L
C
D
Site 60
S774
L
V
G
I
S
P
S
S
E
H
D
V
L
K
E
Site 61
T792
K
K
L
G
G
D
N
T
Q
L
E
A
A
E
W
Site 62
S827
K
H
L
V
M
K
L
S
Y
G
P
E
E
K
D
Site 63
S841
D
M
I
V
M
R
D
S
F
G
I
R
H
P
S
Site 64
S848
S
F
G
I
R
H
P
S
G
H
L
E
H
K
T
Site 65
T855
S
G
H
L
E
H
K
T
I
D
L
V
A
Y
G
Site 66
T878
A
K
T
V
G
L
P
T
A
M
A
A
K
M
L
Site 67
S900
K
G
L
M
G
P
F
S
K
E
I
Y
G
P
I
Site 68
Y904
G
P
F
S
K
E
I
Y
G
P
I
L
E
R
I
Site 69
Y918
I
K
A
E
G
I
I
Y
T
T
Q
S
T
I
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation