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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MALT1
Full Name:
Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Alias:
EC 3.4.22.-; MALT associated translocation; MALT-lymphoma associated translocation; MLT; MLT1; Mucosa associated lymphoid tissue lymphoma translocation gene 1; Mucosa associated lymphoid tissue lymphoma translocation protein 1; Paracaspase
Type:
EC 3.4.22.-; Adaptor/scaffold; Apoptosis; Ligase; Ubiquitin conjugating system; Protease
Mass (Da):
92272
Number AA:
824
UniProt ID:
Q9UDY8
International Prot ID:
IPI00009540
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0032449
GO:0005829
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0004197
GO:0043621
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0050852
GO:0007250
GO:0006916
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
L
L
G
D
P
L
Q
Site 2
T18
L
P
P
S
A
A
P
T
G
P
L
L
A
P
P
Site 3
T29
L
A
P
P
A
G
A
T
L
N
R
L
R
E
P
Site 4
S42
E
P
L
L
R
R
L
S
E
L
L
D
Q
A
P
Site 5
S63
R
L
A
E
L
A
G
S
R
G
R
L
R
L
S
Site 6
S70
S
R
G
R
L
R
L
S
C
L
D
L
E
Q
C
Site 7
S78
C
L
D
L
E
Q
C
S
L
K
V
L
E
P
E
Site 8
S87
K
V
L
E
P
E
G
S
P
S
L
C
L
L
K
Site 9
T130
S
P
P
G
I
K
I
T
V
N
P
E
S
K
A
Site 10
S135
K
I
T
V
N
P
E
S
K
A
V
L
A
G
Q
Site 11
S173
E
I
P
N
G
N
T
S
E
L
I
F
N
A
V
Site 12
Y188
H
V
K
D
A
G
F
Y
V
C
R
V
N
N
N
Site 13
S214
D
V
C
D
I
P
E
S
F
Q
R
S
V
D
G
Site 14
S218
I
P
E
S
F
Q
R
S
V
D
G
V
S
E
S
Site 15
S223
Q
R
S
V
D
G
V
S
E
S
K
L
Q
I
C
Site 16
S225
S
V
D
G
V
S
E
S
K
L
Q
I
C
V
E
Site 17
S235
Q
I
C
V
E
P
T
S
Q
K
L
M
P
G
S
Site 18
Y258
V
G
S
P
I
P
H
Y
Q
W
F
K
N
E
L
Site 19
T268
F
K
N
E
L
P
L
T
H
E
T
K
K
L
Y
Site 20
Y275
T
H
E
T
K
K
L
Y
M
V
P
Y
V
D
L
Site 21
Y279
K
K
L
Y
M
V
P
Y
V
D
L
E
H
Q
G
Site 22
S298
H
V
Y
N
D
R
D
S
Q
D
S
K
K
V
E
Site 23
S301
N
D
R
D
S
Q
D
S
K
K
V
E
I
I
I
Site 24
T387
V
V
S
L
L
D
L
T
E
Y
E
M
R
N
A
Site 25
Y389
S
L
L
D
L
T
E
Y
E
M
R
N
A
V
D
Site 26
Y411
K
G
V
Y
G
L
L
Y
Y
A
G
H
G
Y
E
Site 27
Y412
G
V
Y
G
L
L
Y
Y
A
G
H
G
Y
E
N
Site 28
Y417
L
Y
Y
A
G
H
G
Y
E
N
F
G
N
S
F
Site 29
Y470
M
C
R
K
R
N
D
Y
D
D
T
I
P
I
L
Site 30
T473
K
R
N
D
Y
D
D
T
I
P
I
L
D
A
L
Site 31
S553
Q
A
L
E
I
R
S
S
L
S
E
K
R
A
L
Site 32
S555
L
E
I
R
S
S
L
S
E
K
R
A
L
T
D
Site 33
T561
L
S
E
K
R
A
L
T
D
P
I
Q
G
T
E
Site 34
Y569
D
P
I
Q
G
T
E
Y
S
A
E
S
L
V
R
Site 35
S570
P
I
Q
G
T
E
Y
S
A
E
S
L
V
R
N
Site 36
S573
G
T
E
Y
S
A
E
S
L
V
R
N
L
Q
W
Site 37
T650
P
K
D
A
N
K
G
T
P
E
E
T
G
S
Y
Site 38
S656
G
T
P
E
E
T
G
S
Y
L
V
S
K
D
L
Site 39
Y657
T
P
E
E
T
G
S
Y
L
V
S
K
D
L
P
Site 40
S660
E
T
G
S
Y
L
V
S
K
D
L
P
K
H
C
Site 41
Y669
D
L
P
K
H
C
L
Y
T
R
L
S
S
L
Q
Site 42
T670
L
P
K
H
C
L
Y
T
R
L
S
S
L
Q
K
Site 43
S673
H
C
L
Y
T
R
L
S
S
L
Q
K
L
K
E
Site 44
S674
C
L
Y
T
R
L
S
S
L
Q
K
L
K
E
H
Site 45
S693
V
C
L
S
Y
Q
Y
S
G
L
E
D
T
V
E
Site 46
T698
Q
Y
S
G
L
E
D
T
V
E
D
K
Q
E
V
Site 47
Y737
C
L
M
S
N
G
P
Y
Q
S
S
A
A
T
S
Site 48
S739
M
S
N
G
P
Y
Q
S
S
A
A
T
S
G
G
Site 49
S740
S
N
G
P
Y
Q
S
S
A
A
T
S
G
G
A
Site 50
T743
P
Y
Q
S
S
A
A
T
S
G
G
A
G
H
Y
Site 51
S744
Y
Q
S
S
A
A
T
S
G
G
A
G
H
Y
H
Site 52
S752
G
G
A
G
H
Y
H
S
L
Q
D
P
F
H
G
Site 53
Y761
Q
D
P
F
H
G
V
Y
H
S
H
P
G
N
P
Site 54
S763
P
F
H
G
V
Y
H
S
H
P
G
N
P
S
N
Site 55
S769
H
S
H
P
G
N
P
S
N
V
T
P
A
D
S
Site 56
T772
P
G
N
P
S
N
V
T
P
A
D
S
C
H
C
Site 57
S776
S
N
V
T
P
A
D
S
C
H
C
S
R
T
P
Site 58
S780
P
A
D
S
C
H
C
S
R
T
P
D
A
F
I
Site 59
T782
D
S
C
H
C
S
R
T
P
D
A
F
I
S
S
Site 60
S795
S
S
F
A
H
H
A
S
C
H
F
S
R
S
N
Site 61
S799
H
H
A
S
C
H
F
S
R
S
N
V
P
V
E
Site 62
S801
A
S
C
H
F
S
R
S
N
V
P
V
E
T
T
Site 63
S814
T
T
D
E
I
P
F
S
F
S
D
R
L
R
I
Site 64
S816
D
E
I
P
F
S
F
S
D
R
L
R
I
S
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation