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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLEKHB1
Full Name:
Pleckstrin homology domain-containing family B member 1
Alias:
KPL1; PH domain containing protein in retina 1; PHR1; PHRET1; PKHB1; pleckstriny domain containing, family B (evectins) member 1
Type:
Membrane protein, peripheral
Mass (Da):
27186
Number AA:
243
UniProt ID:
Q9UF11
International Prot ID:
IPI00009635
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004871
PhosphoSite+
KinaseNET
Biological Process:
GO:0007602
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
A
A
P
V
P
P
D
S
A
L
E
S
P
F
E
Site 2
S15
P
P
D
S
A
L
E
S
P
F
E
E
M
A
L
Site 3
Y54
L
D
G
T
L
G
Y
Y
H
D
E
T
A
Q
D
Site 4
T58
L
G
Y
Y
H
D
E
T
A
Q
D
E
E
D
R
Site 5
T97
R
S
R
D
G
L
L
T
V
N
L
R
E
G
G
Site 6
T136
T
P
A
P
A
G
A
T
V
P
P
R
S
R
R
Site 7
S141
G
A
T
V
P
P
R
S
R
R
V
C
S
K
V
Site 8
S146
P
R
S
R
R
V
C
S
K
V
R
C
V
T
R
Site 9
S154
K
V
R
C
V
T
R
S
W
S
P
C
K
V
E
Site 10
S156
R
C
V
T
R
S
W
S
P
C
K
V
E
R
R
Site 11
Y169
R
R
I
W
V
R
V
Y
S
P
Y
Q
D
Y
Y
Site 12
Y172
W
V
R
V
Y
S
P
Y
Q
D
Y
Y
E
V
V
Site 13
Y175
V
Y
S
P
Y
Q
D
Y
Y
E
V
V
P
P
N
Site 14
Y176
Y
S
P
Y
Q
D
Y
Y
E
V
V
P
P
N
A
Site 15
T187
P
P
N
A
H
E
A
T
Y
V
R
S
Y
Y
G
Site 16
Y188
P
N
A
H
E
A
T
Y
V
R
S
Y
Y
G
P
Site 17
Y192
E
A
T
Y
V
R
S
Y
Y
G
P
P
Y
A
G
Site 18
Y193
A
T
Y
V
R
S
Y
Y
G
P
P
Y
A
G
P
Site 19
Y197
R
S
Y
Y
G
P
P
Y
A
G
P
G
V
T
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation